Egonw

Cholesterol metabolism

ROS in COVID-19 endothelial dysfunction

Prion disease pathway

Metabolism of T-2 toxin and HT-2 toxin

Metabolic epileptic disorders

Cancer pathways

ADHD and autism (ASD) pathways

Macrophage-stimulating protein (MSP) signaling

Ovarian infertility

Sulfur degradation

Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins

Aerobic glycolysis

Aerobic glycolysis - augmented

Omega-6-fatty acids in senescence

Sudden infant death syndrome (SIDS) susceptibility pathways

Amino acid metabolism in triple-negative breast cancer cells

Glucose metabolism in triple-negative breast cancer cells

Inflammatory bowel disease signaling

STING pathway in Kawasaki-like disease and COVID-19

Mitochondrial complex I inhibition leading to chemical-induced Fanconi syndrome

Lipids measured in liver metastasis from breast cancer

Degradation pathway of sphingolipids, including diseases

Mecp2 and associated Rett syndrome

Ectodysplasin A signaling in hair follicle development

Wnt myofibroblastic activation of hepatic stellate cells

Interferon type I signaling pathways

Mitochondrial immune response to SARS-CoV-2

GLP-1 secretion from intestine to portal vein

NF1 copy number variation syndrome

Cytokines and inflammatory response

Extrafollicular and follicular B cell activation by SARS-CoV-2

Thiamine metabolic pathways

Hedgehog-related genes

Heme biosynthesis

GLP-1 from intestine and pancreas and role in glucose homeostasis

GLP-1 in pancreatic islet cells

mRNA vaccine activation of dendritic cell and induction of IFN-1

T-cell activation SARS-CoV-2

Measles virus infection

Altered glycosylation of MUC1 in tumor microenvironment

Suppression of HMGB1-mediated inflammation by THBD

LTF danger signal response pathway

Ethanol metabolism production of ROS by CYP2E1

Ethanol metabolism resulting in production of ROS by CYP2E1

Poly(glycerol phosphate) wall teichoic acid biosynthesis

Intracellular auxin transport

Glial cell differentiation

Dopaminergic neurogenesis

Metapathway UDP-glucuronosyltransferases

RAS and bradykinin pathways in COVID-19

Mitochondrial complex inhibition leading to liver injury

Gastric acid production

Immune response to tuberculosis

Serotonin and anxiety-related events

Dengue-2 interactions with complement and coagulation cascades

Downregulation of ACE2 by SARS-CoV-2 spike protein

Physiological and pathological hypertrophy of the heart

15q11q13 copy number variation

3q29 copy number variation syndrome

FLT3 p.Gln640SerfsTer8 signaling pathway

TCA cycle (aka Krebs or citric acid cycle)

Oxidative stress response

Wnt signaling pathway

ATM signaling in development and disease

Steroid biosynthesis

Hypothesized pathways in pathogenesis of cardiovascular disease

Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4)

Glutathione metabolism

Metabolic pathway of LDL, HDL and TG, including diseases

Influence of laminopathies on Wnt signaling

TGF-beta receptor signaling in skeletal dysplasias

FGF23 signaling in hypophosphatemic rickets and related disorders

Autosomal recessive osteopetrosis pathways

Proteoglycan biosynthesis

Endochondral ossification

Effect of progerin on genes involved in progeria

Lamin A processing pathway

Acute viral myocarditis

DNA damage response

Wnt/Beta-catenin signaling inhibitors in current and past clinical trials

GNAQ pathways in port-wine stain

10q11.21q11.23 copy number variation syndrome

Cardiomyocyte signaling pathways converging on titin

Hypoxia-dependent differentiation of myoblasts

Hypoxia-dependent self-renewal of myoblasts

Kisspeptin/kisspeptin receptor system in the ovary

PKC-gamma calcium signaling pathway in ataxia

Thyroid hormones production and peripheral downstream signaling effects

Pathways of nucleic acid metabolism and innate immune sensing

22q11.2 copy number variation syndrome

Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors

Neovascularization processes

miRNA role in immune response in sepsis

Type 2 papillary renal cell carcinoma

PI3K-Akt signaling pathway

miRNA regulation of p53 pathway in prostate cancer

Dysregulated miRNA targeting in insulin/PI3K-AKT signaling

Cell-type dependent selectivity of CCK2R signaling

SIDS susceptibility pathways

Focal adhesion: PI3K-Akt-mTOR signaling pathway

DNA replication

Vitamin A and carotenoid metabolism

N-glycan biosynthesis

DNA replication

Flowering time pathway

Oxytocin signaling

Flowering time pathway

One-carbon metabolism

Thyroxine (thyroid hormone) production

TCA cycle

Estrogen signaling pathway

GABA receptor signaling

Mammary gland development pathway - Involution (Stage 4 of 4)

Mammary gland development pathway - Puberty (Stage 2 of 4)

Mammary gland development pathway - Embryonic development (Stage 1 of 4)

Host-pathogen interaction of human coronaviruses - interferon induction

Drug induction of bile acid pathway

Breast cancer pathway

Drug induction of bile acid pathway

TCA cycle nutrient use and invasiveness of ovarian cancer

Irinotecan pathway

Irinotecan pathway

Angiotensin II receptor type 1 pathway

Aspirin and miRNAs

Evolocumab mechanism to reduce LDL cholesterol

Adverse outcome pathway for mitochondrial complex 1 (C1) inhibition

Polycystic kidney disease pathway

4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression

Regulation of apoptosis by parathyroid hormone-related protein

Vitamin D metabolism

Endometrial cancer

ACE inhibitor pathway

7-oxo-C and 7-beta-HC pathways

Alternative pathway of fetal androgen synthesis

Angiogenesis

Enterohepatic circulation of bile acids

Steroid hormone precursor biosynthesis

Cholesterol biosynthesis with skeletal dysplasias

Oxysterols derived from cholesterol

Disorders of folate metabolism and transport

Bladder cancer

Selenium metabolism and selenoproteins

Glioblastoma signaling pathways

Pilocytic astrocytoma

Riboflavin and CoQ disorders

Linoleic acid metabolism affected by SARS-CoV-2

Melanoma

Vitamin B6-dependent and responsive disorders

Neurotransmitter disorders

Metabolism of sphingolipids in ER and Golgi apparatus

Cell lineage map for neuronal differentiation

Growth factors and hormones in beta cell proliferation

JAK-STAT signaling in the regulation of beta cells

Fatty acids and lipoproteins transport in hepatocytes

Genetic causes of porto-sinusoidal vascular disease

16p11.2 distal deletion syndrome

Cellular proteostasis

Overlap between signal transduction pathways contributing to LMNA laminopathies

Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway

IL-10 anti-inflammatory signaling pathway

Rett syndrome

Lipid metabolism pathway

FTO obesity variant mechanism

Histone modifications

Biotin metabolism

Type II diabetes mellitus

Chronic hyperglycemia impairment of neuron function

Complement-mediated inflammation of pulmonary alveolus in COVID-19 (hypothetical pathway)

COVID-19 structural coverage map

Parkinson's disease pathway

FGFR4 p.G388R signaling pathway

HDAC6 interactions in the central nervous system

Ether lipid biosynthesis

Disorders of fructose metabolism

Disorders of bile acid synthesis and biliary transport

Disorders in ketone body synthesis

Disorders of galactose metabolism

Glyoxylate metabolism

Ethylmalonic encephalopathy

FGFR3 signaling in chondrocyte proliferation and terminal differentiation

Urea cycle and associated pathways

Urea cycle and related diseases

Glycosylation and related congenital defects

Gamma-glutamyl cycle for the biosynthesis and degradation of glutathione, including diseases

Molybdenum cofactor (Moco) biosynthesis

Methionine metabolism leading to sulfur amino acids and related disorders

MTHFR deficiency

Vitamin B12 disorders

Krebs cycle disorders

Pyrimidine metabolism and related diseases

Purine metabolism and related disorders

GABA metabolism (aka GHB)

Hepatitis C and hepatocellular carcinoma

MECP2 and associated Rett syndrome

Complement activation

Mitochondrial fatty acid oxidation disorders

Proline and hydroxyproline pathways

Type I collagen synthesis in the context of osteogenesis imperfecta

Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism

Cerebral organic acidurias, including diseases

Tyrosine metabolism and related disorders

Chromosomal and microsatellite instability in colorectal cancer

Biosynthesis and regeneration of tetrahydrobiopterin and catabolism of phenylalanine

Copper homeostasis

Apoptosis

Codeine and morphine metabolism

Phase I biotransformations, non-P450

Cancer immunotherapy by CTLA4 blockade

Angiopoietin-like protein 8 regulatory pathway

ATM signaling pathway

Amyotrophic lateral sclerosis (ALS)

Cholesterol biosynthesis pathway

Apoptosis modulation and signaling

AMP-activated protein kinase signaling

Fructose and mannose metabolism

KCNQ2-related epilepsies

Glycolysis and gluconeogenesis

Acetylcholine synthesis

Spina bifida

Activation of NLRP3 inflammasome by SARS-CoV-2

Synaptic vesicle pathway

Alzheimer's disease and miRNA effects

Th17 cell differentiation pathway

Focal adhesion

Nucleotide GPCRs

Tryptophan metabolism

Toll-like receptor signaling pathway

Notch signaling pathway

Monoamine GPCRs

Estradiol regulation in porto-sinusoidal vascular disease

Regulation of actin cytoskeleton

Prostaglandin signaling

Hedgehog signaling pathway

G1 to S cell cycle control

Inflammatory response pathway

Fatty acid omega-oxidation

Notch signaling pathway

Fatty acid beta-oxidation 3

Peptide GPCRs

Statin pathway

RIOK1 and RIOK2 in EGFR- and PI3K-mediated tumorigenesis

T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection

Glycine metabolism, including IMDs

Canonical and non-canonical Notch signaling

Sterol regulatory element-binding proteins (SREBP) signaling

p53 transcriptional gene network

Androgen receptor network in prostate cancer

High-osmolarity glycerol (HOG) pathway

MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement

Metapathway biotransformation Phase I and II

Cholestasis

Regucalcin in proximal tubule epithelial kidney cells

Renin-angiotensin-aldosterone system (RAAS)

Hepatitis B infection

Major receptors targeted by epinephrine and norepinephrine

Interleukin-1 (IL-1) structural pathway

ErbB signaling pathway

Non-small cell lung cancer

Methionine de novo and salvage pathway

Non-canonical Wnt pathway

Affected pathways in Duchenne muscular dystrophy

Meta pathway lipodystrophy, dyslipidemia and hyperlipidemia

Hematopoietic stem cell gene regulation by GABP alpha/beta complex

Purine metabolism

Blood clotting cascade

IL-19 signaling pathway

Glycolysis in senescence

Carnosine metabolism of glial cells

Kynurenine pathway and links to cell senescence

Fragile X syndrome

N-glycan biosynthesis

Kallmann syndrome

Pentose phosphate pathway in senescent cells

Smith-Magenis and Potocki-Lupski syndrome copy number variation

Primary ovarian insufficiency

TCA cycle

Kennedy pathway from sphingolipids

Biosynthesis of anthocyanins from phenylalanine in purple corn

Isoglobo series sphingolipids

Pancreatic adenocarcinoma pathway

Ras signaling

ncRNAs involved in Wnt signaling in hepatocellular carcinoma

lncRNA in canonical Wnt signaling and colorectal cancer

5q35 copy number variation

Pleural mesothelioma

Small cell lung cancer

Wnt signaling

Sildenafil treatment

Fibrin complement receptor 3 signaling pathway

Clear cell renal cell carcinoma pathways

Cell cycle

Transcriptional activation by NRF2 in response to phytochemicals

EGFR tyrosine kinase inhibitor resistance

Head and neck squamous cell carcinoma

Cancer immunotherapy by PD-1 blockade

MET in type 1 papillary renal cell carcinoma

Focal adhesion

Complement system

Prader-Willi and Angelman syndrome

11p11.2 copy number variation syndrome

8p23.1 copy number variation syndrome

1p36 copy number variation syndrome

Vitamin K metabolism and activation of dependent proteins

Vitamin A1 and A5/X pathways

Gibberellin A12 biosynthesis

Warburg effect modulated by deubiquitinating enzymes and their substrates

Alanine and aspartate metabolism

Pathophysiological roles of DUX4 in FSHD1

DYRK1A involvement regarding cell proliferation in brain development

DNA adduct formation leading to kidney failure

Cholesterol biosynthesis pathway in hepatocytes

Mineralocorticoid biosynthesis

Estrogen metabolism

Representative anthocyanin biosynthetic pathway

TGFβ/Smad signaling pathway

7q11.23 copy number variation syndrome

Network map of SARS-CoV-2 signaling pathway

17q12 copy number variation syndrome

D-arginine and D-ornithine metabolism

Diet-dependent trimethylamine/trimethylamine N-oxide metabolism

Osteoblast signaling

Genetic alterations of lung cancer

Pantothenate and coenzyme A biosynthesis

Nuclear receptors meta-pathway

Nicotine effect on chromaffin cells

Osteoclast signaling

Induction of autophagy and toll-like receptor signaling pathways by graphene oxide

CAMKK2 pathway

Ergosterol biosynthesis

Electron transport chain: OXPHOS system in mitochondria

Glycerophospholipid biosynthetic pathway

Comprehensive IL-17A signaling

Urotensin-II-mediated signaling pathway

Aryl hydrocarbon receptor pathway

IL-26 signaling pathways

Eicosanoid metabolism via cyclooxygenases (COX)

Abnormal calcium handling and its effects on muscle contraction in DMD

CCL18 signaling pathway

Integrated cancer pathway

VEGF-receptor signal transduction

VEGFR-3 signaling

Glucocorticoid effect on target gene expression

Cori cycle

Peroxisomal beta-oxidation of tetracosanoyl-CoA

Kennedy pathway

Mechanosensory inputs influence pharyngeal activity via ivermectin sensitivity genes

Mechanisms associated with pluripotency

TP53 network

Iron homeostasis

Folate-alcohol and cancer pathway hypotheses

Transcription factors regulate miRNAs related to cardiac hypertrophy

Metapathway signal transduction

MicroRNAs in cardiomyocyte hypertrophy

Energy metabolism

Flavonoid biosynthesis

miRNA regulation of DNA damage response

Regulation of cardiac hypertrophy by miR-208

Oxidative damage response

Glycine metabolism

Opioid receptor pathways

White fat cell differentiation

Dopaminergic neurogenesis

Brain-derived neurotrophic factor (BDNF) signaling pathway

Oncostatin M signaling pathway

Corticotropin-releasing hormone signaling pathway

Interleukin-11 signaling pathway

AGE/RAGE pathway

Thymic stromal lymphopoietin (TSLP) signaling pathway

Heart development

Nicotine effect on dopaminergic neurons

Fluoropyrimidine activity

Mitochondrial long chain fatty acid beta-oxidation

Parkinson's disease

Alpha 6 beta 4 signaling pathway

IL-7 signaling pathway

Target of rapamycin signaling

Photosynthetic carbon reduction

Serotonin transporter activity

IL-4 signaling pathway

VEGFA-VEGFR2 signaling

Apoptosis modulation by HSP70

MAPK signaling pathway

Triacylglyceride synthesis

Osteoblast signaling

Notch signaling

Small ligand GPCRs

Prolactin signaling pathway

TNF-related weak inducer of apoptosis (TWEAK) signaling pathway

Follicle stimulating hormone (FSH) signaling pathway

Leptin signaling pathway

Thyroid stimulating hormone (TSH) signaling pathway

RANKL/RANK signaling pathway

Response regulator aspartate phosphatase interactions

IL-18 signaling pathway

Netrin-UNC5B signaling pathway

Gastrin signaling pathway

Pyrimidine metabolism

Valine, leucine and isoleucine degradation

Androgen receptor signaling pathway

IL-2 signaling pathway

Adipogenesis genes

EGF/EGFR signaling pathway

mRNA processing

Eukaryotic transcription initiation

p38 MAPK signaling pathway

IL6 signaling pathway

Wnt signaling pathway

Fas ligand pathway and stress induction of heat shock proteins

Kit receptor signaling pathway

Nuclear receptors in lipid metabolism and toxicity

Myometrial relaxation and contraction pathways

IL-3 signaling pathway

S1P receptor signal transduction

TOR signaling

CFTR activity in the plasma membrane

TNF-alpha and mucus production in lung epythelium

Intracellular trafficking of CFTR

Interactions between CFTR and other ion channels

Osteopontin signaling

Nucleotide-binding oligomerization domain (NOD) pathway

B cell receptor signaling pathway

IL-9 signaling pathway

IL-1 signaling pathway

Homologous recombination

Integrin-mediated cell adhesion

Bone morphogenic protein signaling and regulation

Pentose phosphate metabolism

IL-5 signaling pathway

Translation factors

TGF-beta receptor signaling

Complement and coagulation cascades

Biogenic amine synthesis

Calcium regulation in cardiac cells

Hypertrophy model

Glucuronidation

Sulfation biotransformation reaction

Tamoxifen metabolism

T-cell receptor signaling pathway

Arachidonate epoxygenase / epoxide hydrolase

Glucose homeostasis

Abscisic acid biosynthesis

Flower development

ID signaling pathway

Glycogen synthesis and degradation

Prostaglandin synthesis and regulation

Pyrimidine ribonucleotide salvage pathways

DNA damage response (only ATM dependent)

Orexin receptor pathway

Autophagy in pancreatic ductal adenocarcinoma

Omega-9 fatty acid synthesis

Eicosanoid metabolism via lipoxygenases (LOX)

Fructose metabolism in proximal tubules

Elongation of (very) long chain fatty acids

Male steroid hormones in cardiomyocyte energy metabolism

Globo series sphingolipid metabolism

Bacterial ceramide synthesis

16p11.2 proximal deletion syndrome

Serotonin receptor 4/6/7 and NR3C signaling

Serotonin receptor 2 and ELK-SRF/GATA4 signaling

Serotonin HTR1 group and FOS pathway

Serotonin transporter activity

Female steroid hormones in cardiomyocyte energy metabolism

Serotonin receptor 4/6/7 and NR3C signaling

Serotonin receptor 2 and ELK-SRF / GATA4 signaling

Serotonin receptor 2 and STAT3 signaling

Serotonin receptor 2 and STAT3 signaling

IL-9 signaling pathway

IL-6 signaling pathway

Lactate shuttle in glial cells

Metabolic pathways of fibroblasts

Protein alkylation leading to liver fibrosis

Cysteine biosynthesis from homoserine

Osteoclast signaling

GPCRs, class A rhodopsin-like

Nuclear factor, erythroid-derived 2, like 2 signaling pathway

Pyruvate dehydrogenase pathway

Sucrose biosynthesis

Colanic acid building blocks biosynthesis

Neurogenesis regulation in the olfactory epithelium

Response to acute ibuprofen exposure

Type I interferon induction and signaling during SARS-CoV-2 infection

Fatty acid biosynthesis

Fatty acid biosynthesis

Fatty acid biosynthesis

Fatty acid biosynthesis

Fatty acid biosynthesis

Fatty acid biosynthesis

Mevalonate pathway

Glycerophospholipid biosynthetic pathway

Wnt signaling pathway and pluripotency

Glycerol teichoic acid biosynthesis

Glycosphingolipid metabolism

Resolvin E1 and resolvin D1 signaling pathways promoting inflammation resolution

Catecholamine synthesis

Burn wound healing

SARS-CoV-2 innate immunity evasion and cell-specific immune response

Oxidative stress and redox pathway

Flavan-3-ol metabolic pathway

Metabolism of tetrahydrocannabinol (THC)

SK UDPglcnac

Cardiac progenitor differentiation

Primary carbon metabolism

Pentose phosphate pathway

Glycolysis

Primary focal segmental glomerulosclerosis (FSGS)

Cardiolipin biosynthesis

DNA replication

Translation factors

Oxidation by cytochrome P450

Pentose phosphate pathway

Ethanol effects on histone modifications

Cholesterol metabolism with Bloch and Kandutsch-Russell pathways

Mitochondrial long chain fatty acid beta-oxidation

Fatty acid oxidation

Phospholipid biosynthesis

Aflatoxin B1 metabolism

Ureide biosynthesis

Heme biosynthesis

Roles of ceramides in development of insulin resistance

TCA cycle in senescence

Deregulation of renin-angiotensin system by SARS-CoV infection

15q11.2 copy number variation syndrome

Neuroinflammation

1q21.1 copy number variation syndrome

Purine metabolism

Sphingolipid metabolism: integrated pathway

Omega-3 / omega-6 fatty acid synthesis

Eicosanoid metabolism via lipooxygenases (LOX)

Eicosanoid metabolism via cytochrome P450 monooxygenases pathway

Omega-3 / omega-6 fatty acid synthesis

Eicosanoid metabolism via cytochrome P450 monooxygenases

Eicosanoid metabolism via cyclooxygenases (COX)

Glycerolipids and glycerophospholipids

Sphingolipid metabolism overview

Fatty acid beta-oxidation 1

De novo biosynthesis of pyrimidine deoxyribonucleotides

Nod-like receptor (NLR) signaling pathway

Pregnane X receptor pathway

Triglyceride biosynthesis

Brassinolide biosynthetic pathway

Sulfide oxidation pathway

Heme biosynthesis

Eicosanoid synthesis

Fatty acid elongation, unsaturated

Selenium micronutrient network

Fatty acid beta-oxidation

Folic acid network

Retinol metabolism

Folic acid network

Fatty acid beta-oxidation

Retinol metabolism

Sulfur amino acid biosynthesis

Triacylglyceride synthesis

Dravet syndrome: Scn1a-A1783V point mutation model

COVID-19 and endothelial cell senescence

Mitochondrial beta-oxidation

Lac-Phe pathway

Lac-Phe pathway

Serotonin reuptake inhibitor response

Bardet-Biedl syndrome

Arsenic metabolism and reactive oxygen species generation

Hippocampal synaptogenesis and neurogenesis

Dravet syndrome

Docosahexaenoic acid oxylipin metabolism

Arachidonate epoxygenase / epoxide hydrolase

Copper homeostasis

Myometrial relaxation and contraction pathways

SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction

COVID-19, thrombosis and anticoagulation

Vitamin D in inflammatory diseases

TLR4 signaling and tolerance

Overview of nanoparticle effects

PDGF pathway

Folate metabolism

Vitamin B12 metabolism

Non-classical role of vitamin D

Steroid biosynthesis

Type II interferon signaling

Retinoblastoma gene in cancer

Glycolysis and gluconeogenesis

Immune responses in the epidermis

Actin cytoskeleton regulation

Nucleotide GPCRs

FAS pathway and stress induction of HSP regulation

Selenium micronutrient network

Blood clotting cascade

Vitamin B12 metabolism

Selenium micronutrient network

Selenium micronutrient network

Folate metabolism

Zinc homeostasis

Hair follicle development: cytodifferentiation - part 3 of 3

Tryptophan degradation via kynurenine

IL1 and megakaryocytes in obesity

Pluripotent stem cell differentiation pathway

Spinal cord injury

Cells and molecules involved in local acute inflammatory response

MAPK pathway in congenital thyroid cancer

HIPK2 in kidney fibrosis

Biogenic amine synthesis

SARS-CoV-2 replication organelle formation

DNA IR-damage and cellular response via ATR

TGF-beta signaling pathway

TNF-alpha signaling pathway

Pathogenesis of SARS-CoV-2 mediated by nsp9-nsp10 complex

Melatonin metabolism and effects

Aryl hydrocarbon receptor pathway

GDNF signaling

SARS-CoV-2 and ACE2 receptor: molecular mechanisms

Wnt signaling pathway

Wnt signaling pathway

GPR143 in melanocytes and retinal pigment epithelium cells

LDLRAD4 and what we know about it

Hijack of ubiquitination by SARS-CoV-2

SARS-CoV-2 and COVID-19 pathway

Wnt signaling pathway

BDNF pathway

RAC1/PAK1/p38/MMP2 pathway

COVID-19 adverse outcome pathway

Ferroptosis

MAPK signaling pathway

Cell cycle

Triacylglyceride synthesis

Wnt signaling pathway and pluripotency

Leptin and adiponectin

Arginine biosynthesis

Fibrin complement receptor 3 signaling pathway

Neuroinflammation and glutamatergic signaling

Serine metabolism

Joubert syndrome

Long-day flowering time pathway

Cell differentiation - index

Burn wound healing

Spinal cord injury

Statin inhibition of cholesterol production

nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell

Interactions of natural killer cells in pancreatic cancer

Beta-oxidation of unsaturated fatty acids

Mevalonate arm of cholesterol biosynthesis pathway with inhibitors

Trehalose degradation, low osmolarity

Effect of L-carnitine on metabolism

Cori cycle

Male infertility

Parkin-ubiquitin proteasomal system pathway

Vitamin D receptor pathway

Nanoparticle triggered regulated necrosis

Burn wound healing

Nod-like receptor (NLR) signaling pathway

Nicotine metabolism in liver cells

Prostaglandin and leukotriene metabolism in senescence

Gut-liver indole metabolism

Tryptophan metabolism

Metabolism of alpha-linolenic acid

Biomarkers for pyrimidine metabolism disorders

Blood clotting and drug effects

Cysteine and methionine catabolism

Role of carnosine in muscle contraction

Hereditary leiomyomatosis and renal cell carcinoma pathway

Host-pathogen interaction of human coronaviruses - MAPK signaling

Oligodendrocyte specification and differentiation, leading to myelin components for CNS

Oxidation by cytochrome P450

Wnt signaling pathway and pluripotency

One-carbon metabolism and related pathways

Primary focal segmental glomerulosclerosis (FSGS)

Familial hyperlipidemia type 4

Familial partial lipodystrophy

Congenital generalized lipodystrophy

Ketogenesis and ketolysis

Vitamin D-sensitive calcium signaling in depression

Biotin metabolism, including IMDs

Urea cycle and metabolism of amino groups

Mammalian disorder of sexual development

EGF/EGFR signaling pathway

Genes associated with the development of rheumatoid arthritis

Distal convoluted tubule 1 (DCT1) cell

NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence

Endoplasmic reticulum stress response in coronavirus infection

Beta-oxidation of unsaturated fatty acids

Fatty acid beta-oxidation meta-pathway

Complement system in neuronal development and plasticity

Valine biosynthesis

Cytokinin signaling

Polar auxin transport

Wnt signaling pathway

Metabolic reprogramming in colon cancer

Ketone bodies synthesis and degradation

Nodal signaling pathway

BMP signaling pathway

Fatty acid beta-oxidation 2

Dauer formation

Proteasome degradation

Mevalonate arm of cholesterol biosynthesis pathway

ERK1-ERK2 MAPK cascade

DNA IR-double strand breaks and cellular response via ATM

Caffeine and theobromine metabolism

Lung fibrosis

Flavonoid pathway

Pentose phosphate pathway

Differentiation of white and brown adipocyte

Mesodermal commitment pathway

Sucrose metabolism

Starch metabolism

ER stress-unfolded protein response (UPRer)

Eukaryotic transcription initiation

miRNAs involved in DNA damage response

FGF signaling pathway

Sphingolipid pathway

Cell division: first embryonic mitosis

Monoamine GPCRs

Cholesterol biosynthesis

Homologous recombination

Deregulation of Rab and Rab effector genes in bladder cancer

De novo biosynthesis of purine nucleotides

Folate biosynthesis

Alpha 6 beta 4 signaling pathway

Wnt signaling pathway and pluripotency

Pentose phosphate pathway

Calcium regulation in cardiac cells

Osteoclast signaling

IL-2 signaling pathway

PDGFR-alpha and STMN1 cooperate to exacerbate cytotoxic effects of vinblastine

TCA cycle

Eicosanoid lipid synthesis map

Triacylglyceride synthesis

BMP signaling pathway in eyelid development

Interleukin-1 induced activation of NF-kB

Glycogen metabolism

Translation factors

Electron transport chain

Neural crest differentiation

GPCRs, class A rhodopsin-like

Endochondral ossification

SIDS susceptibility pathways

Arachidonate epoxygenase / epoxide hydrolase

Catalytic cycle of mammalian flavin-containing monooxygenases (FMOs)

DNA mismatch repair

GPCRs, class C metabotropic glutamate, pheromone

DNA repair pathways, full network

Mitochondrial complex II assembly

Amino acid metabolism pathway excerpt: histidine catabolism extension

GPCRs, class A rhodopsin-like

Acrylamide biotransformation and exposure biomarkers

NO/cGMP/PKG mediated neuroprotection

BMP signaling in eyelid development

TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition

Toll-like receptor signaling related to MyD88

Physico-chemical features and toxicity-associated pathways

Tgif disruption of Shh signaling

lncRNA-mediated mechanisms of therapeutic resistance

Metabolism of dichloroethylene by CYP450

Biochemical pathways: part I

Lipid particles composition

GPCRs, class B secretin-like

Estrogen receptor pathway

Glucocorticoid receptor pathway

Constitutive androstane receptor pathway

Hair follicle development: organogenesis - part 2 of 3

Felbamate metabolism

Cardiac hypertrophic response

Aripiprazole metabolic pathway

Sulindac metabolic pathway

Colchicine metabolic pathway

Diclofenac metabolic pathway

TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc)

Gastric cancer network 2

Gastric cancer network 1

Deregulation of Rab and Rab effector genes in bladder cancer

Endothelin pathways

Fatty acid omega-oxidation

SRF and miRs in smooth muscle differentiation and proliferation

GPCRs, other

Cytokines and inflammatory response

Prostaglandin synthesis and regulation

Nuclear receptors in lipid metabolism and toxicity

IL-9 signaling pathway

IL-2 signaling pathway

Small ligand GPCRs

Fatty acid omega-oxidation

IL-5 signaling pathway

Osteoblast signaling

Cholesterol biosynthesis

ACE inhibitor pathway

Ketone bodies synthesis and degradation

Cytokines and inflammatory response

T cell receptor and co-stimulatory signaling

Neural crest differentiation

Thyroxine (thyroid hormone) production

TWEAK signaling pathway

Thyroid stimulating hormone (TSH) signaling pathway

Aryl hydrocarbon receptor

Differentiation pathway

ATM signaling pathway

Cell differentiation - index

PDGF pathway

TSLP signaling pathway

Spinal cord injury

Nicotine metabolism

Apoptosis modulation and signaling

Polar auxin transport

Isoprenoid precursor biosynthesis in Pf apicoplasts

IGF-1 signaling

Glyoxylate, anapleurotic and succinyl CoA (GAS) pathway

Transcription initiation by sigma factors

Escherichia coli K-12 peripherome

Momilactone biosynthesis

Beta-alanine biosynthesis

Carotenoid biosynthesis

Ganglio sphingolipid metabolism

Cholesterol biosynthesis

Statin pathway

ACE inhibitor pathway

Wnt signaling pathway and pluripotency

Electron transport chain

Cytokines and inflammatory response

IL-2 signaling pathway

Osteoblast signaling

Glycogen metabolism

Endochondral ossification

Notch signaling pathway

Complement and coagulation cascades

IL-4 signaling pathway

TGF-beta receptor signaling

TGF-beta signaling pathway

Statin pathway

Acetylcholine synthesis

ACE inhibitor pathway

IL-3 signaling pathway

Notch signaling pathway

Glycolysis and gluconeogenesis

B cell receptor signaling pathway

Hedgehog signaling pathway

Wnt signaling pathway

Ketone bodies synthesis and degradation

IL-7 signaling pathway

Osteoclast signaling

Electron transport chain

De novo biosynthesis of pyrimidine ribonucleotides

NAD biosynthesis

Pentose phosphate pathway 2

Asparagine biosynthesis

Phenylalanine degradation

De novo NAD biosynthesis

Tyrosine biosynthesis

Glycolysis and gluconeogenesis

MAPK signaling pathway

Glycogen catabolism

Purine fermentation

Methionine degradation

Serine biosynthesis

Threonine and methionine biosynthesis

Histidine, purine, and pyrimidine superpathway

Cell cycle and cell division

Trehalose anabolism

Riboflavin, FMN, and FAD biosynthesis

Fatty acid elongation, saturated

Pentose pathway, non-oxidative branch

Sphingolipid metabolism

Pentose phosphate pathway

Isoleucine and valine biosynthesis

Leucine degradation

Protein modifications

Glycine degradation

Threonine biosynthesis

Allantoin degradation

Nucleotide metabolism

Tryptophan degradation

TCA cycle - detailed

Polyamine biosynthesis

Upiquinone Q prenylation

Phenylalanine, tyrosine, and tryptophan biosynthesis

Starch and cellulose biosynthesis

Aerobic glycerol catabolism

Ribose and deoxyribose phosphate metabolism

Serine and glycine biosynthesis

Isoleucine, leucine, and valine biosynthesis

Glutathione biosynthesis

Phenylalanine biosynthesis

Glutamate biosynthesis superpathway

P-cymene degradation

Leucine biosynthesis

Isoleucine degradation

NAD salvage pathway

Tryptophan biosynthesis

UDP-N-acetylgalactosamine biosynthesis

Fatty acid biosynthesis, initial steps

Cholesterol biosynthesis

DNA replication

Homocysteine and cysteine interconversion

Principal pathways of carbon metabolism

UDP-glucose conversion

mRNA processing

Wnt signaling pathway

MAPK signaling pathway

Mitochondrial long chain fatty acid beta-oxidation

Triacylglycerol biosynthesis

Biosynthesis of gamma-aminobutyric acid (GABA) by polyamine oxidation

Genetic interactions between sugar and hormone signaling

TCA cycle (Krebs cycle)

Chlorophyll b degradation

Flower development: initiation

Heme biosynthesis

Glycogen metabolism

Cholesterol biosynthesis

Calcium regulation in cardiac cells

ACE inhibitor pathway

FAS pathway and stress induction of HSP regulation

Polyol pathway

GPR40 pathway

Imatinib and chronic myeloid leukemia

T cell receptor and co-stimulatory signaling

NAD biosynthesis II (from tryptophan)

Neural crest differentiation

G13 signaling pathway

Wnt signaling pathway

FAS pathway and stress induction of HSP regulation

Heme biosynthesis

Steroid biosynthesis

IL-2 signaling pathway

ACE inhibitor pathway

Complement and coagulation cascades

Translation factors

Mitochondrial unfolded-protein response

Hedgehog signaling pathway

Osteoclast

Apoptosis modulation by HSP70

Oxidative damage response

Amino acid metabolism

Lipid droplet metabolism

Thick ascending limb transporters

Acetylcholine synthesis

IL-1 signaling pathway

Regulation of actin cytoskeleton

TCA cycle

Glucocorticoid metabolism

Proteasome degradation

Heme biosynthesis

Chicken limb development

Sulindac metabolic pathway

Notch signaling pathway

Focal adhesion

Proteasome degradation

Small ligand GPCRs

Proteasome degradation

Statin pathway

Hypothetical network for drug addiction

FAS pathway and stress induction of HSP regulation

Apoptosis modulation by HSP70

DNA replication

PPAR signaling pathway

Glycogen metabolism

Glycolysis and gluconeogenesis

MAPK signaling pathway

p38 MAPK signaling pathway

MAPK signaling pathway

p38 MAPK signaling pathway

Monoamine transport

Amino acid metabolism

Leptin-insulin signaling overlap

Exercise-induced circadian regulation

Synthesis and degradation of ketone bodies

Acetylcholine synthesis

ACE inhibitor pathway

ACE inhibitor pathway

Microglia pathogen phagocytosis pathway

MAPK signaling pathway

Target of rapamycin (TOR) signaling

G13 signaling pathway

p38 Mapk signaling pathway

Common pathways underlying drug addiction

Spinal cord injury

Cytokines and inflammatory response

Glycolysis and gluconeogenesis

Biogenic amine synthesis

Cholesterol biosynthesis

Electron transport chain

p38 MAPK signaling pathway

Cholesterol biosynthesis

MAPK signaling pathway

Ectoderm differentiation

MAPK cascade

Novel Jun-Dmp1 pathway

p38 Mapk signaling pathway

ESC pluripotency pathways

Mapk cascade

FOXA2 pathway

Bile acids synthesis and enterohepatic circulation

Renin-angiotensin system

Insulin signaling in adipocytes (diabetic condition)

Insulin signaling in adipocytes (normal condition)

Tyrobp causal network in microglia

Irinotecan pathway

Glutathione and one-carbon metabolism

Host-pathogen interaction of human coronaviruses - apoptosis

Host-pathogen interaction of human coronaviruses - autophagy

One-carbon metabolism

Biosynthesis of the three types of mycolic acids

Metabolism overview

Trans-sulfuration, one-carbon metabolism and related pathways

Retinoblastoma gene in cancer

One-carbon metabolism and related pathways

One-carbon metabolism

Lactose degradation and galactose metabolism

Disruption of postsynaptic signaling by CNV

PI3K/AKT/mTOR - vitamin D3 signaling

EDA signaling in hair follicle development

Nanomaterial-induced inflammasome activation

BMP2-WNT4-FOXO1 pathway in primary endometrial stromal cell differentiation

MAPK and NFkB signaling pathways inhibited by Yersinia YopJ

Pathways affected in adenoid cystic carcinoma

Farnesoid X receptor pathway

PPAR-alpha pathway

Liver X receptor pathway

Endoderm differentiation

Alzheimer's disease

Nuclear receptors

TNF-alpha signaling pathway

Peptidoglycan cytoplasmic synthesis and recycling pathways

Leptin signaling pathway

IL-1 signaling pathway

FSH signaling pathway

Androgen receptor signaling pathway

Kit receptor signaling pathway

Androgen receptor signaling pathway

ID signaling pathway

Androgen receptor signaling pathway

SARS coronavirus and innate immunity

IL-6 signaling pathway

15q13.3 copy number variation syndrome

Butyrate-induced histone acetylation

Amyotrophic lateral sclerosis (ALS)

Wnt Signaling Pathway and Pluripotency

Alanine and aspartate metabolism

Monoamine GPCRs

Toll-like receptor signaling pathway

Peptide GPCRs

Histidine metabolism

Cholesterol metabolism

Sulfate assimilation and copper detoxification

Lung fibrosis

Synaptic signaling pathways associated with autism spectrum disorder

Unfolded protein response

Phosphoinositides metabolism

Fluoroacetic acid toxicity

RuMP cycle, oxidative branch of the pentose phosphate pathway and formaldehyde assimilation

Nutrient control of ribosomal gene expression

Acetate mediated promotion of metabolic syndrome

Nanoparticle-mediated activation of receptor signaling

Nanomaterial induced apoptosis

Purinergic signaling

Peroxiredoxin 2 induced ovarian failure

Peroxiredoxin 2 induced ovarian failure

Glycosaminoglycan degradation

Nuclear receptors in lipid metabolism and toxicity

Nuclear receptors in lipid metabolism and toxicity

Ptf1a related regulatory pathway

Deoxyribose phosphate metabolism

Tumor suppressor activity of SMARCB1

Hexoses metabolism in proximal tubules

miRNA regulation of prostate cancer signaling pathways

Relationship between inflammation, COX-2 and EGFR

Catalytic cycle of mammalian FMOs

Vanillin and isovanillin metabolism

Metastatic brain tumor

Control of immune tolerance by vasoactive intestinal peptide

Monoamine GPCRs

Aflatoxin B1 metabolism

Estrogen metabolism

Oxidative phosphorylation

Monoamine GPCRs

Biomarkers for urea cycle disorders

Nuclear receptors in lipid metabolism and toxicity

Ethanol metabolism resulting in production of ROS by CYP2E1

Phosphodiesterases in neuronal function

Angiotensin II signaling (acute) in thick ascending limbs

Cytosine methylation

Alanine and aspartate metabolism

Interferon type I signaling pathways

Glutathione metabolism

Gonadotropin-releasing hormone (GnRH) signaling

Cocaine metabolism

Monoamine GPCRs

Lidocaine metabolism

Glucose-1-phosphate metabolism

Cadmium and glutathione

Relationship between glutathione and NADPH

Glycolysis

Dopamine metabolism

Fatty acid oxidation

Geranylgeranyldiphosphate biosynthesis II (plastidic)

Oryzalexin S biosynthesis

Lycopene biosynthesis

Serotonin and anxiety-related events

Serotonin and anxiety

Splicing factor NOVA regulated synaptic proteins

Glutathione metabolism

Nuclear receptors in lipid metabolism and toxicity

Aflatoxin B1 metabolism

Glucuronidation

Glucuronidation

Nuclear receptors in lipid metabolism and toxicity

NRF2 pathway

Iron metabolism in placenta

Novel intracellular components of RIG-I-like receptor pathway

H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity

Caloric restriction and aging

Benzo(a)pyrene metabolism

Arylamine metabolism

Transcriptional activation by NRF2

Estrogen signaling pathway

Monoamine GPCRs

Retinol metabolism

Arylamine metabolism

Thermogenesis

mRNA, protein, and metabolite inducation pathway by cyclosporin A

Benzene metabolism

AtMetExpress overview

Tryptophan metabolism

Biosynthesis and regulation of nematode bile acids

DON mycotoxin biosynthesis

Aflatoxin B1 metabolism

Monoamine GPCRs

Tryptophan metabolism

Estrogen metabolism

Somatroph axis (GH) and its relationship to dietary restriction and aging

Transcription factor regulation in adipogenesis

Genes targeted by miRNAs in adipocytes

Extracellular vesicles in the crosstalk of cardiac cells

Cytosolic DNA-sensing pathway

Butyrate-induced histone acetylation

Glutathione metabolism

Tryptophan metabolism

Calvin cycle

Iron uptake and transport

Glutamate degradation VII

Serine-isocitrate lyase pathway

Gluconeogenesis

Ophthalmate biosynthesis in hepatocytes

Dual hijack model of Vif in HIV infection

Platelet-mediated interactions with vascular and circulating cells

Adipogenesis

Phosphatidylcholine catabolism

Serotonin and anxiety

Nanoparticle triggered autophagic cell death

Nonalcoholic fatty liver disease

Methylerythritol phosphate pathway

Mitochondrial complex I assembly model OXPHOS system

Glutamate degradation III

Glutamate degradation VIII

Glutamate degradation I

Cell engulfment

Tryptophan catabolism leading to NAD+ production

G1 to S cell cycle control

Apoptosis

Lipoic acid metabolism

Ascorbate and aldarate metabolism

Heroin metabolism

Vitamin B9 (folate) biosynthesis pathway

Metapathway biotransformation

ApoE and miR-146 in inflammation and atherosclerosis

SCFA and skeletal muscle substrate metabolism

Glycine biosynthesis

Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling

Sulfate assimilation pathway II

Carbon monoxide dehydrogenase pathway

Glutamate biosynthesis

Toluene degradation

Arginine degradation

Anaerobic respiration

p53 signaling

eIF5A regulation in response to inhibition of the nuclear export system

Glycolysis

Xylulose-monophosphate cycle

Neurotransmitter release in cholinergic motor neurons

Urea cycle and metabolism of amino groups

RTK/Ras/MAPK - LET-23, EGL-15 independent

Toll-like receptor signaling pathway

Nucleotide GPCRs

Lipases biosynthesis

Octane oxidation