Abnormal calcium handling and its effects on muscle contraction in DMD (WP5343)
Homo sapiens
Abnormal calcium handling and its effects on muscle contraction in DMD
Authors
Tom Bausch , Javier Millán Acosta , and Egon WillighagenActivity
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Cited In
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Organisms
Homo sapiensCommunities
Diseases Rare DiseasesAnnotations
Pathway Ontology
altered calcium/calcium-mediated signaling pathway disease pathway muscular disease pathwayDisease Ontology
Duchenne muscular dystrophy atrophic muscular disease muscular diseaseLabel | Type | Compact URI | Comment |
---|---|---|---|
leukotrienes | Metabolite | chebi:25029 | |
lysophospholipids | Metabolite | chebi:16961 | |
Platelet activating factor | Metabolite | chebi:44811 | |
IP3R | Metabolite | chebi:131186 | |
Ca2+ | Metabolite | chebi:29108 | |
prostaglandins | Metabolite | chebi:26333 | |
Ca2+ | Metabolite | chebi:29108 | |
Ca2+ | Metabolite | chebi:29108 | |
Ca2+ | Metabolite | chebi:29108 | |
Ca2+ | Metabolite | chebi:29108 | |
Ca2+ | Metabolite | chebi:29108 | |
Phospholipase A2 | GeneProduct | hgnc.symbol:PLA2G4B | |
CASQ 1 | GeneProduct | hgnc.symbol:CASQ1 | |
Dystrobrevin alpha | GeneProduct | hgnc.symbol:DTNA | |
Calpain 3 | GeneProduct | hgnc.symbol:CAPN3 | |
SERCA 1 | GeneProduct | hgnc.symbol:ATP2A1 | |
Syntrophin beta-1 | GeneProduct | hgnc.symbol:SNTB1 | |
Troponin C | GeneProduct | hgnc.symbol:TNNC2 | |
alpha sarcoglycan | GeneProduct | hgnc.symbol:SGCA | |
RyR 1 | GeneProduct | hgnc.symbol:RYR1 | |
Triadin | GeneProduct | hgnc.symbol:TRDN | |
Voltage gated Ca2+ channel | GeneProduct | hgnc.symbol:CACNG1 | |
Sarcospan | GeneProduct | hgnc.symbol:SSPN | |
Dystrophin | GeneProduct | hgnc.symbol:DMD | |
Dystroglycan 1 | GeneProduct | hgnc.symbol:DAG1 |
References
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- Abnormal Calcium Handling in Duchenne Muscular Dystrophy: Mechanisms and Potential Therapies. Mareedu S, Million ED, Duan D, Babu GJ. Front Physiol. 2021 Apr 9;12:647010. PubMed Europe PMC Scholia
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