Eicosanoid lipid synthesis map (WP4335)
Mus musculus
In biochemistry, eicosanoids are signaling molecules made by oxidation of twenty-carbon essential fatty acids, (EFAs). They exert complex control over many bodily systems, mainly in inflammation or immunity, and as messengers in the central nervous system. Source: [[wikipedia:Eicosanoid|Wikipedia]]. This pathway is inspired by the Lipidmaps>Eicosanoids pathway [https://lipidmaps.org/resources/pathways/vanted.php]. For Homo sapiens, the information from this pathway has been integrated with the pre-existing pathway at [https://www.wikipathways.org/index.php/Pathway:WP167|WikiPathways].
Authors
Egon Willighagen , Denise Slenter , and Eric WeitzActivity
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Organisms
Mus musculusCommunities
Annotations
Pathway Ontology
inflammatory response pathway eicosanoid biosynthetic pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| GP | Metabolite | chebi:37739 | |
| AA | Metabolite | lipidmaps:LMFA01030001 | |
| PGG2 | Metabolite | lipidmaps:LMFA03010009 | |
| PGH2 | Metabolite | lipidmaps:LMFA03010010 | |
| PGE2 | Metabolite | lipidmaps:LMFA03010003 | |
| PGF2a | Metabolite | lipidmaps:LMFA03010002 | |
| PGD2 | Metabolite | wikidata:Q419750 | |
| PGJ2 | Metabolite | wikidata:Q27088353 | |
| 15-deoxy-PGJ2 | Metabolite | pubchem.compound:5311211 | |
| 15-deoxy-PGD2 | Metabolite | pubchem.compound:5283052 | |
| 5-HETE | Metabolite | cas:70608-72-9 | |
| 11-HETE | Metabolite | wikidata:Q27140010 | |
| Pla2g5 | Protein | ncbigene:18784 | |
| Pla2g6 | Protein | ncbigene:53357 | |
| Pla2g4a | Protein | ncbigene:18783 | |
| Pla2g4b | Protein | ncbigene:211429 | |
| Ptgs1 | Protein | ncbigene:74451 | |
| Ptgs2 | Protein | ncbigene:19225 | |
| Ptges | Protein | ncbigene:64292 | |
| Ptgds | Protein | uniprot:O09114 | |
| Alox5 | Protein | ncbigene:11689 |