Tryptophan metabolism (WP3248)

Bos taurus

This pathway describes the metabolism of tryptophan, an essential amino acid. Originally converted from rat to human using ortholog information. Edited by Sebastien Burel

Authors

Martina Summer-Kutmon , Egon Willighagen , Mick Eikelhof , Friederike Ehrhart , and Kristina Hanspers

Activity

last edited

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Cited In

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Organisms

Bos taurus

Communities

Annotations

Pathway Ontology

tryptophan metabolic pathway

Participants

Label Type Compact URI Comment
4-(2-Aminophenyl)-2,4-dioxobutanoate Metabolite chemspider:19951260 4-(2-Aminophenyl)-2,4-dioxobutanoate
Indolelactate Metabolite chemspider:28571995 Indolelactate
Indole-3-acetate Metabolite chemspider:779 Indole-3-acetate
4,8-Dihydroxyquinoline Metabolite chemspider:389608 4,8-Dihydroxyquinoline
4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate Metabolite chemspider:389617 4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate
Oxaloacetate Metabolite chemspider:2509917 Oxaloacetate
3-(2-Aminoethyl)-1H-indol-5-ol Metabolite chemspider:5013 3-(2-Aminoethyl)-1H-indol-5-ol
Indolepyruvate Metabolite chemspider:24775813 Indolepyruvate
Indole-3-acetaldehyde Metabolite chemspider:778 Indole-3-acetaldehyde
5-Methoxyindoleacetate Metabolite chemspider:14533147 5-Methoxyindoleacetate
3-Hydroxyanthranilate Metabolite chemspider:7822291 3-Hydroxyanthranilate
Indole-3-acetaldoxime Metabolite chemspider:388896 Indole-3-acetaldoxime
Indole-3-ethanol Metabolite chemspider:10235
Anthranilate Metabolite chemspider:4573598 Anthranilate
2-Formylaminobenzaldehyde Metabolite chemspider:389
2,3-Dihydroxyindole Metabolite chemspider:20546
Quinolinate Metabolite chemspider:2777129
3-Methoxyanthranilate Metabolite chemspider:7827589 3-Methoxyanthranilate
2-Oxoglutarate Metabolite chemspider:144236 2-Oxoglutarate
2-Oxoadipate Metabolite chemspider:19951093 2-Oxoadipate
5-Hydroxyindoleacetate Metabolite chemspider:10637170 5-Hydroxyindoleacetate
5-(3'-Carboxy-3'-oxopropyl) -4,6-dihydroxypicolinate Metabolite chemspider:30791292 5-(3'-Carboxy-3'-oxopropyl)-4,6-dihydroxypicolinate
5-(2'-Formylethyl)-4,6-dihydroxypicolinate Metabolite chemspider:30791294 5-(2'-Formylethyl)-4,6-dihydroxypicolinate
3-Indoleglycolaldehyde Metabolite chemspider:388979
Formylkynurenine Metabolite cas:1022-31-7 Formylkynurenine
4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate Metabolite hmdb:HMDB0004083
Acetyl-CoA Metabolite cas:72-89-9 Acetyl-CoA
Indole Metabolite cas:120-72-9
5-Methoxytryptamine Metabolite cas:608-07-1
5-Hydroxy-L-tryptophan Metabolite hmdb:HMDB0000472
L-Kynurenine Metabolite cas:343-65-7 L-Kynurenine
Melatonin Metabolite hmdb:HMDB0001389
5-Hydroxykynurenine Metabolite cas:484-78-6
Xanthurenic acid Metabolite hmdb:HMDB0000881
N-Methylserotonin Metabolite hmdb:HMDB0004369
Tryptamine Metabolite cas:61-54-1
5-Hydroxy-N-formylkynurenine Metabolite hmdb:HMDB0004086
4,6-Dihydroxyquinoline Metabolite hmdb:HMDB0004077
N-Acetylisatin Metabolite cas:574-17-4 N-Acetylisatin
L-Tryptophan Metabolite cas:73-22-3
Indole-3-acetamide Metabolite cas:879-37-8 Indole-3-acetamide
Acetoacetyl-CoA Metabolite kegg.compound:C00332
N-Methyltryptamine Metabolite chebi:28136
Crotonoyl-CoA Metabolite kegg.compound:C00877
5-(2'-Carboxyethyl)-4,6-Dihydroxypicolinate Metabolite hmdb:HMDB0006794
3-Indoleacetonitrile Metabolite cas:771-51-7 3-Indoleacetonitrile
5-Hydroxyindoleacetaldehyde Metabolite hmdb:HMDB0004073
2-Aminophenol Metabolite cas:95-55-6 2-Aminophenol
6-Hydroxymelatonin Metabolite cas:2208-41-5
Glutaryl-CoA Metabolite kegg.compound:C00527
N-Acetylserotonin Metabolite cas:1210-83-9 N-Acetylserotonin
CYP4F12 GeneProduct ensembl:ENSBTAG00000038549 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:66002
UBR5 GeneProduct ensembl:ENSBTAG00000021209 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:51366
IDO1 GeneProduct ensembl:ENSBTAG00000020602 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3620
CYP2E1 GeneProduct ensembl:ENSBTAG00000018365 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1571
RNF25 GeneProduct ensembl:ENSBTAG00000003817 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:64320
GCDH GeneProduct ensembl:ENSBTAG00000016211 predicted
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2639
ALDH9A1 GeneProduct ensembl:ENSBTAG00000017852 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:223
HRMT1L2 GeneProduct ensembl:ENSBTAG00000001357 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3276
ALDH2 GeneProduct ensembl:ENSBTAG00000008743 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:217
ALDH1A2 GeneProduct ensembl:ENSBTAG00000010119 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8854
ASMT GeneProduct ensembl:ENSBTAG00000047124 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:438
CYP1A1 GeneProduct ensembl:ENSBTAG00000001021 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1543
MDM2 GeneProduct ensembl:ENSBTAG00000010422 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4193
OGDH GeneProduct ensembl:ENSBTAG00000006029 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4967
MAOB GeneProduct ensembl:ENSBTAG00000001288 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4129
ALDH3A2 GeneProduct ensembl:ENSBTAG00000039161 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:224
DDC GeneProduct ensembl:ENSBTAG00000020869 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1644
HSD17B10 GeneProduct ensembl:ENSBTAG00000017779 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3028
CAT GeneProduct ensembl:ENSBTAG00000020980 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:847
UBE3A GeneProduct ensembl:ENSBTAG00000002487 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7337
HADH GeneProduct ensembl:ENSBTAG00000002049 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3033
CYP3A4 GeneProduct ensembl:ENSBTAG00000047379 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1576
CYP7B1 GeneProduct ensembl:ENSBTAG00000001299 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9420
AADAT GeneProduct ensembl:ENSBTAG00000010326 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:51166
ACAT1 GeneProduct ensembl:ENSBTAG00000012885 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:38
KYNU GeneProduct ensembl:ENSBTAG00000032277 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8942
AFMID GeneProduct ensembl:ENSBTAG00000007125 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:125061
CYP1B1 GeneProduct ensembl:ENSBTAG00000010531 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1545
AANAT GeneProduct ensembl:ENSBTAG00000014682 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:15
AOX1 GeneProduct ensembl:ENSBTAG00000009725 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:316
DHCR24 GeneProduct ensembl:ENSBTAG00000004688 predicted
HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1718
ACMSD GeneProduct ensembl:ENSBTAG00000008039 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:130013
CYP1A2 GeneProduct ensembl:ENSBTAG00000000085 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1544
CYP2C18 GeneProduct ensembl:ENSBTAG00000020375 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1562
WARS GeneProduct ensembl:ENSBTAG00000004679 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7453
CYP2A13 GeneProduct ensembl:ENSBTAG00000047815 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1553
INMT GeneProduct ensembl:ENSBTAG00000001448 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:11185
CYP19A1 GeneProduct ensembl:ENSBTAG00000014890 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1588
ALDH1A1 GeneProduct ensembl:ENSBTAG00000008103 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:216
CYP2J2 GeneProduct ensembl:ENSBTAG00000013693 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1573
HAAO GeneProduct ensembl:ENSBTAG00000004674 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:23498
ABP1 GeneProduct ensembl:ENSBTAG00000005419 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:26
ECHS1 GeneProduct ensembl:ENSBTAG00000017710 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1892
TDO2 GeneProduct ensembl:ENSBTAG00000011062 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6999
CYP2F1 GeneProduct ensembl:ENSBTAG00000046805 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1572
TPH1 GeneProduct ensembl:ENSBTAG00000005343 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7166

References