Nicotine activity on dopaminergic neurons (WP3179)

Bos taurus

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Authors

Martina Summer-Kutmon , Eric Weitz , and Egon Willighagen

Activity

last edited

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Cited In

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Organisms

Bos taurus

Communities

Annotations

Cell Type Ontology

dopaminergic neuron

Pathway Ontology

nicotine drug pathway

Participants

Label Type Compact URI Comment
Na+ Metabolite hmdb:HMDB0000588
Dopamine Metabolite hmdb:HMDB0000073
Tyrosine Metabolite hmdb:HMDB0000158
ATP Metabolite hmdb:HMDB0000538
Ca++ Metabolite hmdb:HMDB0000464
K+ Metabolite hmdb:HMDB0000586
DOPA Metabolite hmdb:HMDB0000181
Nicotine Metabolite hmdb:HMDB0001934
cAMP Metabolite hmdb:HMDB0000058
CHRNA4 GeneProduct ensembl:ENSBTAG00000017198 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1137
GNAI1 GeneProduct ensembl:ENSBTAG00000002714 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2770
TH GeneProduct ensembl:ENSBTAG00000026768 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7054
PRKACA GeneProduct ensembl:ENSBTAG00000006642 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5566
DRD2 GeneProduct ensembl:ENSBTAG00000010860 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1813
CDK5 GeneProduct ensembl:ENSBTAG00000007766 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1020
PPP1R1B GeneProduct ensembl:ENSBTAG00000006035 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:84152
DRD3 GeneProduct ensembl:ENSBTAG00000002132 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1814
ADCY2 GeneProduct ensembl:ENSBTAG00000019210 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:108
DDC GeneProduct ensembl:ENSBTAG00000020869 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1644
CHRNA5 GeneProduct ensembl:ENSBTAG00000013657 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1138
CHRNB2 GeneProduct ensembl:ENSBTAG00000007517 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1141
GNB1 GeneProduct ensembl:ENSBTAG00000000215 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2782
KCNK9 GeneProduct ensembl:ENSBTAG00000047488 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:51305
SLC18A2 GeneProduct ensembl:ENSBTAG00000004739 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6571
CHRNA6 GeneProduct ensembl:ENSBTAG00000014056 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8973
PPP1CA GeneProduct ensembl:ENSBTAG00000040418 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5499
GNG2 GeneProduct ensembl:ENSBTAG00000003043 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:54331
KCNK3 GeneProduct ensembl:ENSBTAG00000018193 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3777
CHRNA3 GeneProduct ensembl:ENSBTAG00000003130 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1136

References

  1. Circadian variations of the activity and induction of tyrosine aminotransferase after x-irradiation. Stefan M, Boerescu J, Gheorghe N. Physiologie. 1975;12(3):229–31. PubMed Europe PMC Scholia
  2. Conservative therapy of coronary heart disease. Kaltenbach M. Verh Dtsch Ges Kreislaufforsch. 1975;41:74–9. PubMed Europe PMC Scholia
  3. Integrating genotype and phenotype information: an overview of the PharmGKB project. Pharmacogenetics Research Network and Knowledge Base. Klein TE, Chang JT, Cho MK, Easton KL, Fergerson R, Hewett M, et al. Pharmacogenomics J. 2001;1(3):167–70. PubMed Europe PMC Scholia
  4. The vesicular amine transporter family (SLC18): amine/proton antiporters required for vesicular accumulation and regulated exocytotic secretion of monoamines and acetylcholine. Eiden LE, Schäfer MKH, Weihe E, Schütz B. Pflugers Arch. 2004 Feb;447(5):636–40. PubMed Europe PMC Scholia
  5. A biochemical and functional protein complex involving dopamine synthesis and transport into synaptic vesicles. Cartier EA, Parra LA, Baust TB, Quiroz M, Salazar G, Faundez V, et al. J Biol Chem. 2010 Jan 15;285(3):1957–66. PubMed Europe PMC Scholia