Biogenic amine synthesis (WP125)

Drosophila melanogaster

Biogenic amines are one of two broad classes of classical neurotransmitters (the other being amino acids) and include: acetylcholine, serotonin, histamine, and the catecholamines epinephrine, norepinephrine, and dopamine. Source: http://www.whatislife.com/reader2/Metabolism/pathway/Neurotransmitter.html

Authors

Alex Pico , Thomas Kelder , Egon Willighagen , Christine Chichester , Martina Summer-Kutmon , Krasin , Elisson nl , Eric Weitz , and Kristina Hanspers

Activity

last edited

Discuss this pathway

Check for ongoing discussions or start your own.

Cited In

Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.

Organisms

Drosophila melanogaster

Communities

Annotations

Pathway Ontology

biogenic amine biosynthetic pathway

Participants

Label Type Compact URI Comment
Epinephrine Metabolite hmdb:HMDB00068
Dopamine Metabolite hmdb:HMDB00073
Tyrosine Metabolite chebi:17895
Norepinephrine Metabolite hmdb:HMDB00216
Histidine Metabolite hmdb:HMDB00177
GABA Metabolite chebi:16865
Phenylalanine Metabolite chebi:17295
Glutamate Metabolite chebi:14321
Choline Metabolite hmdb:HMDB00097
Acetylserotonin Metabolite hmdb:HMDB01238
Histamine Metabolite hmdb:HMDB00870
L-Dopa Metabolite hmdb:HMDB00181
Acetylcholine Metabolite hmdb:HMDB00895
Tryptophan Metabolite hmdb:HMDB00929
Melatonin Metabolite hmdb:HMDB01389
Serotonin Metabolite hmdb:HMDB00259
5-Hydroxy-L-tryptophan Metabolite hmdb:HMDB00472
ACHE GeneProduct ensembl:ENSG00000087085
Ddc GeneProduct ncbigene:35190
Trh GeneProduct ncbigene:38121
PNMT GeneProduct ensembl:ENSG00000141744
Ddc GeneProduct ncbigene:35190
Hn GeneProduct ncbigene:38871
ple GeneProduct ncbigene:38746
Tbh GeneProduct ncbigene:31718
Hdc GeneProduct ncbigene:36076
AANAT GeneProduct ensembl:ENSG00000129673
GAD2 GeneProduct ensembl:ENSG00000136750
MAOA GeneProduct ensembl:ENSG00000189221
ASMT GeneProduct ensembl:ENSG00000196433
Ddc GeneProduct ncbigene:35190
MAOA GeneProduct ensembl:ENSG00000189221
Cha GeneProduct ncbigene:42249
Gad1 GeneProduct ncbigene:38484
COMT GeneProduct ncbigene:47091

References