Tryptophan metabolism (WP1126)

Canis familiaris

This pathway describes the metabolism of tryptophan, an essential amino acid. Original pathway was converted from rat to human using ortholog information. Edited by Sebastien Burel

Authors

Egon Willighagen , Friederike Ehrhart , and Kristina Hanspers

Activity

last edited

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Cited In

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Organisms

Canis familiaris

Communities

Annotations

Pathway Ontology

tryptophan metabolic pathway

Participants

Label Type Compact URI Comment
Formylkynurenine Metabolite cas:1022-31-7 Formylkynurenine
4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate Metabolite hmdb:HMDB0004083
Acetyl-CoA Metabolite cas:72-89-9 Acetyl-CoA
Indole Metabolite cas:120-72-9
5-Methoxytryptamine Metabolite cas:608-07-1
5-Hydroxy-L-tryptophan Metabolite hmdb:HMDB0000472
L-Kynurenine Metabolite cas:343-65-7 L-Kynurenine
Melatonin Metabolite hmdb:HMDB0001389
5-Hydroxykynurenine Metabolite cas:484-78-6
Xanthurenic acid Metabolite hmdb:HMDB0000881
N-Methylserotonin Metabolite hmdb:HMDB0004369
Tryptamine Metabolite cas:61-54-1
5-Hydroxy-N-formylkynurenine Metabolite hmdb:HMDB0004086
4,6-Dihydroxyquinoline Metabolite hmdb:HMDB0004077
N-Acetylisatin Metabolite cas:574-17-4 N-Acetylisatin
L-Tryptophan Metabolite cas:73-22-3
Indole-3-acetamide Metabolite cas:879-37-8 Indole-3-acetamide
Acetoacetyl-CoA Metabolite kegg.compound:C00332
N-Methyltryptamine Metabolite chebi:28136
Crotonoyl-CoA Metabolite kegg.compound:C00877
5-(2'-Carboxyethyl)-4,6-Dihydroxypicolinate Metabolite hmdb:HMDB0006794
3-Indoleacetonitrile Metabolite cas:771-51-7 3-Indoleacetonitrile
5-Hydroxyindoleacetaldehyde Metabolite hmdb:HMDB0004073
2-Aminophenol Metabolite cas:95-55-6 2-Aminophenol
6-Hydroxymelatonin Metabolite cas:2208-41-5
Glutaryl-CoA Metabolite kegg.compound:C00527
N-Acetylserotonin Metabolite cas:1210-83-9 N-Acetylserotonin
UBR5 GeneProduct ncbigene:475055
IDO1 GeneProduct ncbigene:475574
CYP2E1 GeneProduct ncbigene:415128
RNF25 GeneProduct ncbigene:478912
GCDH GeneProduct ncbigene:476696 predicted
ALDH9A1 GeneProduct ncbigene:478991
PRMT1 GeneProduct ncbigene:476411
ALDH2 GeneProduct ncbigene:610941
ALDH1A2 GeneProduct ncbigene:478319
LOC100683688 GeneProduct ncbigene:100683688
CYP1A1 GeneProduct ncbigene:100686778
MDM2 GeneProduct ncbigene:403693
OGDH GeneProduct ncbigene:475499
MAOB GeneProduct ncbigene:403451
ALDH3A2 GeneProduct ncbigene:479518
DDC GeneProduct ncbigene:606852
HSD17B10 GeneProduct ncbigene:480930
CAT GeneProduct ncbigene:403474
UBE3A GeneProduct ncbigene:479010
HADH GeneProduct ncbigene:478506
CYP7B1 GeneProduct ncbigene:486973
AADAT GeneProduct ncbigene:486059
ACAT1 GeneProduct ncbigene:489421
KYNU GeneProduct ncbigene:483907
AFMID GeneProduct ncbigene:609011
CYP1B1 GeneProduct ncbigene:483038
AANAT GeneProduct ncbigene:483331
AOX1 GeneProduct ncbigene:608820
DHCR24 GeneProduct ncbigene:489573 predicted
ACMSD GeneProduct ncbigene:476125
CYP1A2 GeneProduct ncbigene:494010
CYP2C19 GeneProduct ncbigene:415122
WARS GeneProduct ncbigene:480435
CYP2A13 GeneProduct ncbigene:484494
CYP19A1 GeneProduct ncbigene:494003
ALDH1A1 GeneProduct ncbigene:476323
CYP2J2 GeneProduct ncbigene:610195
HAAO GeneProduct ncbigene:611728
ABP1 GeneProduct ncbigene:475536
ECHS1 GeneProduct ncbigene:480828
TDO2 GeneProduct ncbigene:475476
LOC612477 GeneProduct ncbigene:612477
TPH1 GeneProduct ncbigene:611956

References