GPCRs, class B secretin-like (WP334)

Homo sapiens

This pathway was created using the GPCRDB (Horn et al., 1998), http://www.gpcr.org/7tm/ (originally at http://www.cmbi.kun.nl/7tm/). The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references.

Authors

Nathan Salomonis , Alex Pico , Bruce Conklin , Kristina Hanspers , Egon Willighagen , and Eric Weitz

Activity

last edited

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Cited In

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Organisms

Homo sapiens

Communities

Annotations

Pathway Ontology

G protein mediated signaling pathway

Participants

Label Type Compact URI Comment
CALCR GeneProduct ncbigene:799
CALCRL GeneProduct ncbigene:10203
CRHR1 GeneProduct ncbigene:1394
CRHR2 GeneProduct ncbigene:1395
GIPR GeneProduct ncbigene:2696
GLP2R GeneProduct ncbigene:9340
GLP1R GeneProduct ncbigene:2740
GCGR GeneProduct ncbigene:2642
GHRHR GeneProduct ncbigene:2692
PTHR2 GeneProduct ncbigene:5746
PTHR1 GeneProduct ncbigene:5745
ADCYAP1R1 GeneProduct ncbigene:117
SCTR GeneProduct ncbigene:6344
VIPR1 GeneProduct ncbigene:7433
VIPR2 GeneProduct ncbigene:7434
CD97 GeneProduct ncbigene:976
EMR1 GeneProduct ncbigene:2015
EMR2 GeneProduct ncbigene:30817
LPHN1 GeneProduct ncbigene:22859
LPHN2 GeneProduct ncbigene:23266
LPHN3 GeneProduct ncbigene:23284
ELTD1 GeneProduct ncbigene:64123
GPR64 GeneProduct ncbigene:10149

References

  1. GPCRDB: an information system for G protein-coupled receptors. Horn F, Weare J, Beukers MW, Hörsch S, Bairoch A, Chen W, et al. Nucleic Acids Res. 1998 Jan 1;26(1):275–9. PubMed Europe PMC Scholia
  2. Classifying G-protein coupled receptors with support vector machines. Karchin R, Karplus K, Haussler D. Bioinformatics. 2002 Jan;18(1):147–59. PubMed Europe PMC Scholia