GPCRs, class B secretin-like (WP334)
Homo sapiens
This pathway was created using the GPCRDB (Horn et al., 1998), http://www.gpcr.org/7tm/ (originally at http://www.cmbi.kun.nl/7tm/). The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references.
Authors
Nathan Salomonis , Alex Pico , Bruce Conklin , Kristina Hanspers , Egon Willighagen , and Eric WeitzActivity
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Cited In
- Bioinformatics and system biology approach to identify the influences of SARS-CoV-2 infections to idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease patients (2021).
- Transcriptome Alterations In X-Irradiated Human Gingiva Fibroblasts (2016).
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Organisms
Homo sapiensCommunities
Annotations
Pathway Ontology
G protein mediated signaling pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| CALCR | GeneProduct | ncbigene:799 | |
| CALCRL | GeneProduct | ncbigene:10203 | |
| CRHR1 | GeneProduct | ncbigene:1394 | |
| CRHR2 | GeneProduct | ncbigene:1395 | |
| GIPR | GeneProduct | ncbigene:2696 | |
| GLP2R | GeneProduct | ncbigene:9340 | |
| GLP1R | GeneProduct | ncbigene:2740 | |
| GCGR | GeneProduct | ncbigene:2642 | |
| GHRHR | GeneProduct | ncbigene:2692 | |
| PTHR2 | GeneProduct | ncbigene:5746 | |
| PTHR1 | GeneProduct | ncbigene:5745 | |
| ADCYAP1R1 | GeneProduct | ncbigene:117 | |
| SCTR | GeneProduct | ncbigene:6344 | |
| VIPR1 | GeneProduct | ncbigene:7433 | |
| VIPR2 | GeneProduct | ncbigene:7434 | |
| CD97 | GeneProduct | ncbigene:976 | |
| EMR1 | GeneProduct | ncbigene:2015 | |
| EMR2 | GeneProduct | ncbigene:30817 | |
| LPHN1 | GeneProduct | ncbigene:22859 | |
| LPHN2 | GeneProduct | ncbigene:23266 | |
| LPHN3 | GeneProduct | ncbigene:23284 | |
| ELTD1 | GeneProduct | ncbigene:64123 | |
| GPR64 | GeneProduct | ncbigene:10149 |
References
- GPCRDB: an information system for G protein-coupled receptors. Horn F, Weare J, Beukers MW, Hörsch S, Bairoch A, Chen W, et al. Nucleic Acids Res. 1998 Jan 1;26(1):275–9. PubMed Europe PMC Scholia
- Classifying G-protein coupled receptors with support vector machines. Karchin R, Karplus K, Haussler D. Bioinformatics. 2002 Jan;18(1):147–59. PubMed Europe PMC Scholia