Small ligand GPCRs (WP971)
Bos taurus
G protein–coupled receptors (GPCRs) which are also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses. Coupling with G proteins, they are called seven-transmembrane receptors because they pass through the cell membrane seven times. Source: [https://en.wikipedia.org/wiki/G_protein–coupled_receptor Wikipedia] These small ligand receptors are part of the Rhodopsin-like family of GPCRs. Source: [https://en.wikipedia.org/wiki/Rhodopsin-like_receptors Wikipedia]
Authors
Martina Summer-Kutmon , Kristina Hanspers , Egon Willighagen , and Eric WeitzActivity
Discuss this pathway
Check for ongoing discussions or start your own.
Cited In
Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.
Organisms
Bos taurusCommunities
Annotations
Pathway Ontology
G protein mediated signaling pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| Prostanoids | Metabolite | chebi:26347 | |
| Melatonin | Metabolite | chebi:16796 | |
| LysophosphatidicAcid | Metabolite | wikidata:Q2823281 | |
| Cannabinoid | Metabolite | chebi:67194 | |
| CNR1 | GeneProduct | ensembl:ENSBTAG00000046006 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1268 |
| CNR2 | GeneProduct | ensembl:ENSBTAG00000019371 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1269 |
| S1PR1 | GeneProduct | ensembl:ENSBTAG00000005990 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1901 |
| LPAR1 | GeneProduct | ensembl:ENSBTAG00000009654 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1902 |
| S1PR3 | GeneProduct | ensembl:ENSBTAG00000011374 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1903 |
| S1PR2 | GeneProduct | ensembl:ENSBTAG00000002738 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9294 |
| S1PR4 | GeneProduct | ensembl:ENSBTAG00000000381 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8698 |
| MTNR1A | GeneProduct | ensembl:ENSBTAG00000046938 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4543 |
| PTAFR | GeneProduct | ensembl:ENSBTAG00000027051 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5724 |
| PTGDR | GeneProduct | ensembl:ENSBTAG00000006703 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5729 |
| EP1 | GeneProduct | ensembl:ENSBTAG00000017041 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5731 |
| PTGER2 | GeneProduct | ensembl:ENSBTAG00000002163 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5732 |
| PTGER3 | GeneProduct | ensembl:ENSBTAG00000019230 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5733 |
| PTGER4 | GeneProduct | ensembl:ENSBTAG00000014972 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5734 |
| FP | GeneProduct | ensembl:ENSBTAG00000015902 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5737 |
| PTGIR | GeneProduct | ensembl:ENSBTAG00000014585 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5739 |
| TBXA2R | GeneProduct | ensembl:ENSBTAG00000014944 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6915 |
| GPR50 | GeneProduct | ensembl:ENSBTAG00000005950 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000102195 |