Fatty acid biosynthesis (WP1020)

Bos taurus

The production of fatty acids from acetyl-CoA and NADPH through the use of enzymes known as fatty acid synthases is referred to as fatty acid synthesis. This biological process occurs within the cytoplasm of cells. The majority of acetyl-CoA that is transformed into fatty acids originates from carbohydrates through the glycolytic pathway.

Authors

Martina Summer-Kutmon , Eric Weitz , Egon Willighagen , and Alex Pico

Activity

last edited

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Organisms

Bos taurus

Communities

Annotations

Pathway Ontology

fatty acid biosynthetic pathway

Participants

Label Type Compact URI Comment
Oxaloacetate Metabolite chemspider:2509917
Palmitate Metabolite chemspider:440215
Citrate Metabolite chemspider:29081
Pyruvate Metabolite chemspider:96901
Long-Chain fatty acid Metabolite chebi:15904
Malonyl-CoA Metabolite cas:524-14-1
Acetyl-CoA Metabolite cas:72-89-9
Acyl-CoA (n+2) Metabolite chebi:17984
FASN GeneProduct ensembl:ENSBTAG00000015980 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2194
ECHS1 GeneProduct ensembl:ENSBTAG00000017710 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1892
ACSL5 GeneProduct ensembl:ENSBTAG00000006707 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:51703
PECR GeneProduct ensembl:ENSBTAG00000006821 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:55825
ECHDC2 GeneProduct ensembl:ENSBTAG00000002910 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:55268
ECHDC1 GeneProduct ensembl:ENSBTAG00000003887 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:55862
ACSL4 GeneProduct ensembl:ENSBTAG00000018986 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2182
SCD GeneProduct ensembl:ENSBTAG00000047957 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6319
ACSS2 GeneProduct ensembl:ENSBTAG00000013303 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:55902
ECHDC3 GeneProduct ensembl:ENSBTAG00000012377 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:79746
ACLY GeneProduct ensembl:ENSBTAG00000016740 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:47
ACSL3 GeneProduct ensembl:ENSBTAG00000017258 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2181
HADH GeneProduct ensembl:ENSBTAG00000002049 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3033
ACACB GeneProduct ensembl:ENSBTAG00000022058 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:32
ACSL1 GeneProduct ensembl:ENSBTAG00000004344 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2180
PC GeneProduct ensembl:ENSBTAG00000019700 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5091
ACAA2 GeneProduct ensembl:ENSBTAG00000002863 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10449
MECR GeneProduct ensembl:ENSBTAG00000017253 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:51102
DECR1 GeneProduct ensembl:ENSBTAG00000019663 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1666
ACSL6 GeneProduct ensembl:ENSBTAG00000019708 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:23305
ECH1 GeneProduct ensembl:ENSBTAG00000016313 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1891

References