Monoamine GPCRs (WP1076)
Bos taurus
G protein–coupled receptors (GPCRs) which are also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses. Coupling with G proteins, they are called seven-transmembrane receptors because they pass through the cell membrane seven times. Source: [https://en.wikipedia.org/wiki/G_protein–coupled_receptor Wikipedia] Monoamine GPCRs are Rhodopsin-like GPCRs that bind to monoamine neurotransmitters. [https://en.wikipedia.org/wiki/Monoamine_neurotransmitter Monoamine neurotransmitters]
Authors
Egon Willighagen , Martina Summer-Kutmon , Denise Slenter , and Kristina HanspersActivity
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Organisms
Bos taurusCommunities
Annotations
Pathway Ontology
G protein mediated signaling pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| Serotonin | Metabolite | cas:50-67-9 | |
| Epinephrine | Metabolite | hmdb:HMDB0000068 | |
| Norepinephrine | Metabolite | hmdb:HMDB0000216 | |
| Acetylcholine | Metabolite | hmdb:HMDB0000895 | |
| Muscarine | Metabolite | chebi:7034 | |
| Histamine | Metabolite | cas:51-45-6 | |
| Dopamine | Metabolite | cas:62-31-7 | |
| HRH1 | GeneProduct | ensembl:ENSBTAG00000001447 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3269 |
| HTR4 | GeneProduct | ensembl:ENSBTAG00000010837 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3360 |
| DRD3 | GeneProduct | ensembl:ENSBTAG00000002132 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1814 |
| HRH2 | GeneProduct | ensembl:ENSBTAG00000044071 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3274 |
| CHRM3 | GeneProduct | ensembl:ENSBTAG00000008059 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1131 |
| ADRA1A | GeneProduct | ensembl:ENSBTAG00000031632 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:148 |
| DBDR | GeneProduct | ensembl:ENSBTAG00000038606 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1816 |
| ADRB3 | GeneProduct | ensembl:ENSBTAG00000017981 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:155 |
| ADRA1B | GeneProduct | ensembl:ENSBTAG00000040253 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:147 |
| CHRM2 | GeneProduct | ensembl:ENSBTAG00000014674 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1129 |
| HTR6 | GeneProduct | ensembl:ENSBTAG00000007996 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3362 |
| HTR1D | GeneProduct | ensembl:ENSBTAG00000040329 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3352 |
| CHRM1 | GeneProduct | ensembl:ENSBTAG00000011579 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1128 |
| HTR1E | GeneProduct | ensembl:ENSBTAG00000026580 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3354 |
| HTR7 | GeneProduct | ensembl:ENSBTAG00000008783 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3363 |
| CHRM4 | GeneProduct | ensembl:ENSBTAG00000033699 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1132 |
| DRD2 | GeneProduct | ensembl:ENSBTAG00000010860 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1813 |
| CHRM5 | GeneProduct | ensembl:ENSBTAG00000037985 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1133 |
| HTR2A | GeneProduct | ensembl:ENSBTAG00000013498 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3356 |
| 5HTR1F | GeneProduct | ensembl:ENSBTAG00000039151 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3355 |
| DRD1 | GeneProduct | ensembl:ENSBTAG00000047719 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1812 |
| HTR5A | GeneProduct | ensembl:ENSBTAG00000002891 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3361 |
| ADRB1 | GeneProduct | ensembl:ENSBTAG00000001242 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:153 |
| 5HTR2B | GeneProduct | ensembl:ENSBTAG00000039772 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3357 |
| 5HTR1A | GeneProduct | ensembl:ENSBTAG00000040439 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3350 |
| ADRA1D | GeneProduct | ensembl:ENSBTAG00000019504 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:146 |
| HTR1B | GeneProduct | ensembl:ENSBTAG00000037429 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3351 |
| ADRB2 | GeneProduct | ensembl:ENSBTAG00000002144 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:154 |