Prostaglandin synthesis and regulation (WP98)

Homo sapiens

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Cited In

• Identification of biomarkers and pathways for the SARS-CoV-2 infections that make complexities in pulmonary arterial hypertension patients (2021).
• Long Term Culture of the A549 Cancer Cell Line Promotes Multilamellar Body Formation and Differentiation towards an Alveolar Type II Pneumocyte Phenotype (2016).
• Identification of the effects of COVID-19 on patients with pulmonary fibrosis and lung cancer: a bioinformatics analysis and literature review (2022).
• Human Monocytes Exposed to SARS-CoV-2 Display Features of Innate Immune Memory Producing High Levels of CXCL10 upon Restimulation (2023).
• Single-cell ‘omic profiles of human aortic endothelial cells in vitro and human atherosclerotic lesions ex vivo reveal heterogeneity of endothelial subtype and response to activating perturbations (2024).

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References

1. Identification of a principal mRNA species for human 3alpha-hydroxysteroid dehydrogenase isoform (AKR1C3) that exhibits high prostaglandin D2 11-ketoreductase activity. Matsuura K, Shiraishi H, Hara A, Sato K, Deyashiki Y, Ninomiya M, et al. J Biochem. 1998 Nov;124(5):940–6. PubMed Europe PMC Scholia
2. Gene knockout mice in the study of parturition. Gross G, Imamura T, Muglia LJ. J Soc Gynecol Investig. 2000;7(2):88–95. PubMed Europe PMC Scholia
3. FPRP, a major, highly stoichiometric, highly specific CD81- and CD9-associated protein. Stipp CS, Orlicky D, Hemler ME. J Biol Chem. 2001 Feb 16;276(7):4853–62. PubMed Europe PMC Scholia
4. Mammalian class Sigma glutathione S-transferases: catalytic properties and tissue-specific expression of human and rat GSH-dependent prostaglandin D2 synthases. Jowsey IR, Thomson AM, Flanagan JU, Murdock PR, Moore GB, Meyer DJ, et al. Biochem J. 2001 Nov 1;359(Pt 3):507–16. PubMed Europe PMC Scholia
5. The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs. Reid G, Wielinga P, Zelcer N, van der Heijden I, Kuil A, de Haas M, et al. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9244–9. PubMed Europe PMC Scholia
6. MITF is necessary for generation of prostaglandin D2 in mouse mast cells. Morii E, Oboki K. J Biol Chem. 2004 Nov 19;279(47):48923–9. PubMed Europe PMC Scholia
7. SOX9 regulates prostaglandin D synthase gene transcription in vivo to ensure testis development. Wilhelm D, Hiramatsu R, Mizusaki H, Widjaja L, Combes AN, Kanai Y, et al. J Biol Chem. 2007 Apr 6;282(14):10553–60. PubMed Europe PMC Scholia
8. AKR1C2 and AKR1C3 mediated prostaglandin D2 metabolism augments the PI3K/Akt proliferative signaling pathway in human prostate cancer cells. Wang S, Yang Q, Fung KM, Lin HK. Mol Cell Endocrinol. 2008 Jul 16;289(1–2):60–6. PubMed Europe PMC Scholia
9. The human aldose reductase AKR1B1 qualifies as the primary prostaglandin F synthase in the endometrium. Bresson E, Boucher-Kovalik S, Chapdelaine P, Madore E, Harvey N, Laberge PY, et al. J Clin Endocrinol Metab. 2011 Jan;96(1):210–9. PubMed Europe PMC Scholia
10. Expression of aldo-keto reductase family 1 member C1 (AKR1C1) gene in porcine ovary and uterine endometrium during the estrous cycle and pregnancy. Seo KS, Naidansuren P, Kim SH, Yun SJ, Park JJ, Sim BW, et al. Reprod Biol Endocrinol. 2011 Oct 20;9:139. PubMed Europe PMC Scholia
11. In vitro effect of peroxisome proliferator activated receptor (PPAR) ligands on prostaglandin E2 synthesis and secretion by porcine endometrium during the estrous cycle and early pregnancy. Bogacka I, Bogacki M, Gaglewska M, Kurzynska A, Wasielak M. J Physiol Pharmacol. 2013 Feb;64(1):47–54. PubMed Europe PMC Scholia