EBV LMP1 signaling (WP1243)

Mus musculus

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Authors

Christine Chichester , Martina Summer-Kutmon , and Egon Willighagen

Activity

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Cited In

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Organisms

Mus musculus

Communities

Annotations

Pathway Ontology

Epstein-Barr virus infection pathway

Participants

Label Type Compact URI Comment
Map3k3 GeneProduct ensembl:ENSMUSG00000020700
Nfkb2 GeneProduct ensembl:ENSMUSG00000025225
Mapk8 GeneProduct ensembl:ENSMUSG00000021936
Tnf GeneProduct ensembl:ENSMUSG00000024401
Rela GeneProduct ensembl:ENSMUSG00000024927
Pdlim7 GeneProduct ensembl:ENSMUSG00000021493
Tradd GeneProduct ensembl:ENSMUSG00000031887
Ifnb1 GeneProduct ensembl:ENSMUSG00000048806
Ikbkb GeneProduct ensembl:ENSMUSG00000031537
Traf6 GeneProduct ensembl:ENSMUSG00000027164
Chuk GeneProduct ensembl:ENSMUSG00000025199
Map3k7 GeneProduct ensembl:ENSMUSG00000028284
Nfkb1 GeneProduct ensembl:ENSMUSG00000028163
Irak1 GeneProduct ensembl:ENSMUSG00000031392
Traf1 GeneProduct ensembl:ENSMUSG00000026875
Ccl5 GeneProduct ensembl:ENSMUSG00000035042
Map3k14 GeneProduct ensembl:ENSMUSG00000020941
Chuk GeneProduct ncbigene:12675
Ikbkg GeneProduct ensembl:ENSMUSG00000004221
Ccl20 GeneProduct ensembl:ENSMUSG00000026166
Mapk1 GeneProduct ensembl:ENSMUSG00000063358
Hsp90aa1 GeneProduct ncbigene:15519

References

  1. TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappaB. Uemura N, Kajino T, Sanjo H, Sato S, Akira S, Matsumoto K, et al. J Biol Chem. 2006 Mar 24;281(12):7863–72. PubMed Europe PMC Scholia
  2. IL-1 receptor-associated kinase 1 is critical for latent membrane protein 1-induced p65/RelA serine 536 phosphorylation and NF-kappaB activation. Song YJ, Jen KY, Soni V, Kieff E, Cahir-McFarland E. Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2689–94. PubMed Europe PMC Scholia
  3. Expression and regulation of the CC-chemokine ligand 20 during human tuberculosis. Lee JS, Lee JY, Son JW, Oh JH, Shin DM, Yuk JM, et al. Scand J Immunol. 2008 Jan;67(1):77–85. PubMed Europe PMC Scholia
  4. Hypoxia transcriptionally induces macrophage-inflammatory protein-3alpha/CCL-20 in primary human mononuclear phagocytes through nuclear factor (NF)-kappaB. Battaglia F, Delfino S, Merello E, Puppo M, Piva R, Varesio L, et al. J Leukoc Biol. 2008 Mar;83(3):648–62. PubMed Europe PMC Scholia