Neurotransmitter release cycle (WP3192)

Bos taurus

Authors

Martina Summer-Kutmon , Elisa Cirillo , and Eric Weitz

Activity

Discuss this pathway

Check for ongoing discussions or start your own.

Cited In

Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.

Organisms

Bos taurus

Communities

Annotations

Pathway Ontology

signaling pathway signaling pathway pertinent to the brain and nervous system

References

1. Human choline acetyltransferase (CHAT): partial gene sequence and potential control regions. Toussaint JL, Geoffroy V, Schmitt M, Werner A, Garnier JM, Simoni P, et al. Genomics. 1992 Feb;12(2):412–6. PubMed Europe PMC Scholia
2. Purification of phosphate-dependent glutaminase from isolated mitochondria of Ehrlich ascites-tumour cells. Quesada AR, Sanchez-Jimenez F, Perez-Rodriguez J, Marquez J, Medina MA, Nuñez de Castro I. Biochem J. 1988 Nov 1;255(3):1031–5. PubMed Europe PMC Scholia
3. Determination of delta pH in cholinergic synaptic vesicles: its effect on storage and release of acetylcholine. Michaelson DM, Angel I. Life Sci. 1980 Jul 7;27(1):39–44. PubMed Europe PMC Scholia
4. Functional identification of a vesicular acetylcholine transporter and its expression from a “cholinergic” gene locus. Erickson JD, Varoqui H, Schäfer MK, Modi W, Diebler MF, Weihe E, et al. J Biol Chem. 1994 Sep 2;269(35):21929–32. PubMed Europe PMC Scholia
5. A human synaptic vesicle monoamine transporter cDNA predicts posttranslational modifications, reveals chromosome 10 gene localization and identifies TaqI RFLPs. Surratt CK, Persico AM, Yang XD, Edgar SR, Bird GS, Hawkins AL, et al. FEBS Lett. 1993 Mar 8;318(3):325–30. PubMed Europe PMC Scholia
6. Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A. Brunner HG, Nelen M, Breakefield XO, Ropers HH, van Oost BA. Science. 1993 Oct 22;262(5133):578–80. PubMed Europe PMC Scholia
7. Cloning and characterization of two human polyspecific organic cation transporters. Gorboulev V, Ulzheimer JC, Akhoundova A, Ulzheimer-Teuber I, Karbach U, Quester S, et al. DNA Cell Biol. 1997 Jul;16(7):871–81. PubMed Europe PMC Scholia
8. Interaction of Munc-18-2 with syntaxin 3 controls the association of apical SNAREs in epithelial cells. Riento K, Galli T, Jansson S, Ehnholm C, Lehtonen E, Olkkonen VM. J Cell Sci. 1998 Sep;111 ( Pt 17):2681–8. PubMed Europe PMC Scholia
9. Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles. Augustin I, Rosenmund C, Südhof TC, Brose N. Nature. 1999 Jul 29;400(6743):457–61. PubMed Europe PMC Scholia
10. Molecular cloning, sequencing and expression studies of the human breast cancer cell glutaminase. Gómez-Fabre PM, Aledo JC, Del Castillo-Olivares A, Alonso FJ, Núñez De Castro I, Campos JA, et al. Biochem J. 2000 Jan 15;345 Pt 2(Pt 2):365–75. PubMed Europe PMC Scholia
11. Immunoisolation of GABA-specific synaptic vesicles defines a functionally distinct subset of synaptic vesicles. Takamori S, Riedel D, Jahn R. J Neurosci. 2000 Jul 1;20(13):4904–11. PubMed Europe PMC Scholia
12. Identification of a vesicular glutamate transporter that defines a glutamatergic phenotype in neurons. Takamori S, Rhee JS, Rosenmund C, Jahn R. Nature. 2000 Sep 14;407(6801):189–94. PubMed Europe PMC Scholia
13. Modulation of amyloid precursor protein metabolism by X11alpha /Mint-1. A deletion analysis of protein-protein interaction domains. Mueller HT, Borg JP, Margolis B, Turner RS. J Biol Chem. 2000 Dec 15;275(50):39302–6. PubMed Europe PMC Scholia
14. Cloning and analysis of unique human glutaminase isoforms generated by tissue-specific alternative splicing. Elgadi KM, Meguid RA, Qian M, Souba WW, Abcouwer SF. Physiol Genomics. 1999 Aug 31;1(2):51–62. PubMed Europe PMC Scholia
15. Functional characterization of the human high-affinity choline transporter. Okuda T, Haga T. FEBS Lett. 2000 Nov 3;484(2):92–7. PubMed Europe PMC Scholia
16. Rab3a binding and secretion-enhancing domains in Rim1 are separate and unique. Studies in adrenal chromaffin cells. Sun L, Bittner MA, Holz RW. J Biol Chem. 2001 Apr 20;276(16):12911–7. PubMed Europe PMC Scholia
17. Glutamine uptake by neurons: interaction of protons with system a transporters. Chaudhry FA, Schmitz D, Reimer RJ, Larsson P, Gray AT, Nicoll R, et al. J Neurosci. 2002 Jan 1;22(1):62–72. PubMed Europe PMC Scholia
18. Phosphorylation of Munc18 by protein kinase C regulates the kinetics of exocytosis. Barclay JW, Craig TJ, Fisher RJ, Ciufo LF, Evans GJO, Morgan A, et al. J Biol Chem. 2003 Mar 21;278(12):10538–45. PubMed Europe PMC Scholia
19. Rim, a component of the presynaptic active zone and modulator of exocytosis, binds 14-3-3 through its N terminus. Sun L, Bittner MA, Holz RW. J Biol Chem. 2003 Oct 3;278(40):38301–9. PubMed Europe PMC Scholia
20. The synaptic vesicle cycle. Sudhof TC. Annu Rev Neurosci. 2004;27:509–47. PubMed Europe PMC Scholia
21. Munc18-1 stabilizes syntaxin 1, but is not essential for syntaxin 1 targeting and SNARE complex formation. Toonen RFG, de Vries KJ, Zalm R, Südhof TC, Verhage M. J Neurochem. 2005 Jun;93(6):1393–400. PubMed Europe PMC Scholia
22. Expression of GFP-tagged neuronal glutamate transporters in cerebellar Purkinje neurons. Meera P, Dodson PD, Karakossian MH, Otis TS. Neuropharmacology. 2005 Nov;49(6):883–9. PubMed Europe PMC Scholia
23. Localization of the Na(+)-coupled neutral amino acid transporter 2 in the cerebral cortex. Melone M, Varoqui H, Erickson JD, Conti F. Neuroscience. 2006 Jun 19;140(1):281–92. PubMed Europe PMC Scholia
24. The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer. Bak LK, Schousboe A, Waagepetersen HS. J Neurochem. 2006 Aug;98(3):641–53. PubMed Europe PMC Scholia
25. Vesicle pools, docking, priming, and release. Becherer U, Rettig J. Cell Tissue Res. 2006 Nov;326(2):393–407. PubMed Europe PMC Scholia
26. Molecular organization of the presynaptic active zone. Schoch S, Gundelfinger ED. Cell Tissue Res. 2006 Nov;326(2):379–91. PubMed Europe PMC Scholia
27. Munc18-1 binds directly to the neuronal SNARE complex. Dulubova I, Khvotchev M, Liu S, Huryeva I, Südhof TC, Rizo J. Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2697–702. PubMed Europe PMC Scholia
28. How synaptotagmin promotes membrane fusion. Martens S, Kozlov MM, McMahon HT. Science. 2007 May 25;316(5828):1205–8. PubMed Europe PMC Scholia
29. Identification of the substrate binding region of vesicular monoamine transporter-2 (VMAT-2) using iodoaminoflisopolol as a novel photoprobe. Gopalakrishnan A, Sievert M, Ruoho AE. Mol Pharmacol. 2007 Dec;72(6):1567–75. PubMed Europe PMC Scholia
30. The neurotransmitter cycle and quantal size. Edwards RH. Neuron. 2007 Sep 20;55(6):835–58. PubMed Europe PMC Scholia
31. Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids. Stein A, Radhakrishnan A, Riedel D, Fasshauer D, Jahn R. Nat Struct Mol Biol. 2007 Oct;14(10):904–11. PubMed Europe PMC Scholia
32. Dual modes of Munc18-1/SNARE interactions are coupled by functionally critical binding to syntaxin-1 N terminus. Khvotchev M, Dulubova I, Sun J, Dai H, Rizo J, Südhof TC. J Neurosci. 2007 Nov 7;27(45):12147–55. PubMed Europe PMC Scholia
33. Sensorineural deafness and seizures in mice lacking vesicular glutamate transporter 3. Seal RP, Akil O, Yi E, Weber CM, Grant L, Yoo J, et al. Neuron. 2008 Jan 24;57(2):263–75. PubMed Europe PMC Scholia
34. Syntaxin 1A interaction with the dopamine transporter promotes amphetamine-induced dopamine efflux. Binda F, Dipace C, Bowton E, Robertson SD, Lute BJ, Fog JU, et al. Mol Pharmacol. 2008 Oct;74(4):1101–8. PubMed Europe PMC Scholia
35. A novel mechanism for GABA synthesis and packaging into synaptic vesicles. Buddhala C, Hsu CC, Wu JY. Neurochem Int. 2009;55(1–3):9–12. PubMed Europe PMC Scholia