Metabolic reprogramming in colon cancer (WP4290)

Homo sapiens

Authors

Kristina Hanspers , Egon Willighagen , and Alex Pico

Activity

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Cited In

• Ten simple rules for creating reusable pathway models for computational analysis and visualization (2021).
• The double dealing of cyclin D1 (2020).
• Investigation of the relationship between COVID-19 and pancreatic cancer using bioinformatics and systems biology approaches (2024).

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Organisms

Homo sapiens

Communities

CPTAC Diseases

Annotations

Pathway Ontology

altered carbohydrate metabolic pathway cancer pathway

Disease Ontology

colorectal cancer

References

1. Urinary organic acids in man. I. Normal patterns. Lawson AM, Chalmers RA, Watts RW. Clin Chem. 1976 Aug;22(8):1283–7. PubMed Europe PMC Scholia
2. Citrate synthesis in intact rat-liver mitochondria is irreversible. Greksák M, Lopes-Cardozo M, van den Bergh SG. Eur J Biochem. 1982 Feb;122(2):423–7. PubMed Europe PMC Scholia
3. Isotopomer analysis of citric acid cycle and gluconeogenesis in rat liver. Reversibility of isocitrate dehydrogenase and involvement of ATP-citrate lyase in gluconeogenesis. Des Rosiers C, Di Donato L, Comte B, Laplante A, Marcoux C, David F, et al. J Biol Chem. 1995 Apr 28;270(17):10027–36. PubMed Europe PMC Scholia
4. Modeling of liver citric acid cycle and gluconeogenesis based on 13C mass isotopomer distribution analysis of intermediates. Fernandez CA, Des Rosiers C. J Biol Chem. 1995 Apr 28;270(17):10037–42. PubMed Europe PMC Scholia
5. Characterization of the ATP- and GTP-specific succinyl-CoA synthetases in pigeon. The enzymes incorporate the same alpha-subunit. Johnson JD, Muhonen WW, Lambeth DO. J Biol Chem. 1998 Oct 16;273(42):27573–9. PubMed Europe PMC Scholia
6. The alpha-ketoglutarate dehydrogenase complex. Sheu KF, Blass JP. Ann N Y Acad Sci. 1999;893:61–78. PubMed Europe PMC Scholia
7. The conversion of citrate into cis-aconitate and isocitrate in the presence of aconitase. KREBS HA, HOLZACH O. Biochem J. 1952 Nov;52(3):527–8. PubMed Europe PMC Scholia