Fatty acid beta-oxidation (WP143)
Homo sapiens
Complete fatty acid beta-oxidation pathway for saturated and unsaturated fatty acids. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP143 CPTAC Assay Portal]
Authors
Michiel Adriaens , Chris Evelo , Susan Coort , Patrick Ahles , Ferry Jagers , Adrien Defay , Alex Pico , Egon Willighagen , Martina Summer-Kutmon , Denise Slenter , Priyanka K , Kristina Hanspers , Licong , and Eric WeitzActivity
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Cited In
- Phenotypic and functional characterization of corneal endothelial cells during in vitro expansion (2020).
- Introducing WikiPathways as a Data-Source to Support Adverse Outcome Pathways for Regulatory Risk Assessment of Chemicals and Nanomaterials (2018).
- Exploring the cellular network of metabolic flexibility in the adipose tissue (2018).
- Copy number variations in high and low fertility breeding boars (2015).
- A network biology workflow to study transcriptomics data of the diabetic liver (2014).
- New Insight Into Mechanisms of Hepatic Encephalopathy: An Integrative Analysis Approach to Identify Molecular Markers and Therapeutic Targets.
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Organisms
Homo sapiensCommunities
CPTAC Lipids and LIPID MAPS Serious Request 2024 - MetaKidsAnnotations
Pathway Ontology
fatty acid metabolic pathway fatty acid beta degradation pathway fatty acid degradation pathwayDisease Ontology
lipid metabolism disorderLabel | Type | Compact URI | Comment |
---|---|---|---|
trans,cis-Lauro-2,6-dienoyl-CoA | Metabolite | chebi:28387 | |
3-Oxododexanoyl-CoA | Metabolite | pubchem.compound:11966169 | |
Fatty Acid | Metabolite | chebi:35366 | |
Glutarate | Metabolite | pubchem.compound:743 | |
Trans-Oct-2-enoyl-CoA | Metabolite | chebi:27537 | |
Myristoyl-CoA | Metabolite | chebi:15532 | |
(S)-3-Hydroxytetradecanoyl-CoA | Metabolite | chebi:27466 | |
Acetyl-CoA | Metabolite | cas:72-89-9 | |
Glutaryl-CoA | Metabolite | chebi:15524 | |
Glyceraldehyde-3-Phosphate | Metabolite | cas:591-57-1 | |
2-trans-dodecenoyl-CoA | Metabolite | chebi:15471 | |
Glycerol | Metabolite | cas:56-81-5 | |
cis,cis-3,6-Dodecadienoyl-CoA | Metabolite | chebi:28002 | |
Trans-Dec-2-enoyl-CoA | Metabolite | chebi:10723 | |
3-Oxo-octanoyl-CoA | Metabolite | chebi:28264 | |
3-Oxohexanoyl-CoA | Metabolite | chebi:27648 | |
2-trans-4-cis-decadienoyl-CoA | Metabolite | chebi:29119 | |
Butanoyl-CoA | Metabolite | chebi:15517 | |
Decanoyl-CoA | Metabolite | chebi:28493 | |
Linoleoyl-CoA | Metabolite | cas:40757-80-0 | |
3-Oxopalmitoyl-CoA | Metabolite | chebi:15491 | |
Dihydroxyacetone Phosphate | Metabolite | cas:57-04-5 | |
Trans-Hex-2-enoyl-CoA | Metabolite | chebi:28706 | |
(S)-3-Hydroxyhexadecanoyl-CoA | Metabolite | chebi:27402 | |
(S)-3-Hydroxybutanoyl-CoA | Metabolite | chebi:15453 | |
Lauroyl-CoA | Metabolite | cas:6244-92-4 | |
Hexanoyl-CoA | Metabolite | chebi:27540 | |
L-Glycerol-3-Phosphate | Metabolite | chebi:15978 | |
Acyl-CoA | Metabolite | chebi:17984 | |
(S)-3-Hydroxydecanoyl-CoA | Metabolite | chebi:28325 | |
(S)-3-Hydroxyoctanoyl-CoA | Metabolite | chebi:28632 | |
Palmitoyl-CoA | Metabolite | chebi:15525 | |
Acetoacetyl-CoA | Metabolite | cas:1420-36-6 | |
3-trans-decenoyl-CoA | Metabolite | chebi:29126 | |
Triacylglycerol | Metabolite | chebi:17855 | |
HADHA | GeneProduct | ncbigene:3030 | |
ACADM | GeneProduct | ncbigene:34 | |
HADHB | GeneProduct | ncbigene:3032 | |
PNPLA2 | GeneProduct | ncbigene:57104 | |
CPT2 | GeneProduct | ncbigene:1376 | |
ACADS | GeneProduct | ncbigene:35 | |
DCI | GeneProduct | ncbigene:1632 | |
ECHS1 | GeneProduct | ncbigene:1892 | |
GCDH | GeneProduct | ncbigene:2639 | |
HADHSC | GeneProduct | ncbigene:3033 | |
ACADVL | GeneProduct | ncbigene:37 | |
GPD2 | GeneProduct | ncbigene:2820 | |
ACSL5 | GeneProduct | ncbigene:51703 | |
DLD | GeneProduct | ncbigene:1738 | |
ACAS2 | GeneProduct | ncbigene:55902 | |
TPI1 | GeneProduct | ncbigene:7167 | |
GK2 | GeneProduct | ncbigene:2712 | |
ACSL1 | GeneProduct | ncbigene:2180 | |
DECR1 | GeneProduct | ncbigene:1666 | |
LIPC | GeneProduct | ncbigene:3990 | |
SLC25A20 | GeneProduct | ncbigene:788 | |
ACADL | GeneProduct | ncbigene:33 | |
CRAT | GeneProduct | ncbigene:1384 | |
LIPE | GeneProduct | ncbigene:3991 | |
ACSL6 | GeneProduct | ncbigene:23305 | |
CPT1A | GeneProduct | ncbigene:1374 | |
CPT1B | GeneProduct | ncbigene:1375 | |
ACSL4 | GeneProduct | ncbigene:2182 | |
GK | GeneProduct | ncbigene:2710 | |
LIPF | GeneProduct | ncbigene:8513 | |
CHKB | GeneProduct | ncbigene:1120 | |
ACAT1 | GeneProduct | ncbigene:38 | |
ACSL3 | GeneProduct | ncbigene:2181 | |
LPL | GeneProduct | ncbigene:4023 |
References
- Enzymes of fatty acid beta-oxidation in developing brain. Reichmann H, Maltese WA, DeVivo DC. J Neurochem. 1988 Aug;51(2):339–44. PubMed Europe PMC Scholia