VEGF-receptor signal transduction (WP1965)

Rattus norvegicus

Open in new tab Open in Newt (SBGN)
Download PNG Download SVG Download JSON Download GPML Learn more about Downloads
VEGF Signal transduction in haematopoeitic stem cells, macrophages, monocyten, vascular endothelium and lymphatic endothelium.

Authors

Camiel Hoogendoorn , Kristina Hanspers , Martina Summer-Kutmon , Daniela Digles , Eric Weitz , and Egon Willighagen

Activity

last edited

Discuss this pathway

Check for ongoing discussions or start your own.

Cited In

Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.

Organisms

Rattus norvegicus

Communities

Annotations

Pathway Ontology

vascular endothelial growth factor signaling pathway

Participants

Label Type Compact URI Comment
PIP3 Metabolite hmdb:HMDB0010147
IP3 Metabolite hmdb:HMDB0001498
PIP2 Metabolite hmdb:HMDB0010032
PI3K GeneProduct ensembl:ENSRNOG00000000145
PKC GeneProduct ensembl:ENSRNOG00000003491
DAG GeneProduct ensembl:ENSRNOG00000019400
GRB2 GeneProduct ensembl:ENSRNOG00000003990
VEGF-A GeneProduct ensembl:ENSRNOG00000019598
Plcg1 GeneProduct ensembl:ENSRNOG00000051490
VRAP GeneProduct ensembl:ENSRNOG00000013294
Akt/PKB GeneProduct ensembl:ENSRNOG00000028629
VEGF-C GeneProduct ensembl:ENSRNOG00000011416
VEGF-B GeneProduct ensembl:ENSRNOG00000021156
Sck GeneProduct ensembl:ENSRNOG00000020657 Shc like
Raf GeneProduct ensembl:ENSRNOG00000010153
Ras GeneProduct ensembl:ENSRNOG00000009338
FAK GeneProduct ensembl:ENSRNOG00000023923
PXN GeneProduct ensembl:ENSRNOG00000001149
Src GeneProduct ensembl:ENSRNOG00000009495
MAPKAPK2/3 GeneProduct ncbigene:289014
HSP27 GeneProduct ensembl:ENSRNOG00000017795
SHC GeneProduct ensembl:ENSRNOG00000020657
PKC GeneProduct ensembl:ENSRNOG00000009652
p42 MAPK GeneProduct ensembl:ENSRNOG00000001849
p44 MAPK GeneProduct ensembl:ENSRNOG00000001849
BAD GeneProduct ensembl:ENSRNOG00000021147
Caspase 9 GeneProduct ensembl:ENSRNOG00000012944
eNOS GeneProduct ensembl:ENSRNOG00000009348
RAC GeneProduct ensembl:ENSRNOG00000001068
SPK Protein uniprot:P0C6C0
PlGF Protein uniprot:Q63434
VEGF-D Protein uniprot:O35251
p38MAPK Protein uniprot:ENSRNOG00000006984

References

  1. VEGF-receptor signal transduction. Cross MJ, Dixelius J, Matsumoto T, Claesson-Welsh L. Trends Biochem Sci. 2003 Sep;28(9):488–94. PubMed Europe PMC Scholia