Methionine degradation (WP46)
Saccharomyces cerevisiae
Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. Description from KEGG.
Authors
Jessica Heckman , Egon Willighagen , Daniela Digles , Denise Slenter , Alex Pico , Eric Weitz , and Kristina HanspersActivity
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Organisms
Saccharomyces cerevisiaeCommunities
Annotations
Pathway Ontology
classic metabolic pathway methionine degradation pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| phosphate | Metabolite | cas:14265-44-2 | |
| L-methionine | Metabolite | cas:63-68-3 | |
| homocysteine | Metabolite | cas:6027-13-0 | |
| adenosine | Metabolite | cas:58-61-7 | |
| diphosphate | Metabolite | cas:2466-09-3 |