Biosynthesis and regulation of nematode bile acids (WP2293)

Caenorhabditis elegans

Open in new tab Open in Newt (SBGN)
Download PNG Download SVG Download JSON Download GPML Learn more about Downloads

Authors

Anwesha Bohler , Christine Chichester , Egon Willighagen , and Alex Pico

Activity

last edited

Discuss this pathway

Check for ongoing discussions or start your own.

Cited In

Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.

Organisms

Caenorhabditis elegans

Communities

Annotations

Pathway Ontology

bile acid biosynthetic pathway

Participants

Label Type Compact URI Comment
Cholesterol Metabolite hmdb:HMDB0000067
7-Dehydrocholesterol Metabolite hmdb:HMDB0000032
Lathosterol Metabolite hmdb:HMDB0001170
Lathosterone Metabolite chebi:71550
Cholestenone Metabolite hmdb:HMDB0000921
DAF-36 GeneProduct ensembl:WBGene00007536
EMB-8 GeneProduct ensembl:WBGene00001262
DAF-9 GeneProduct ensembl:T13C5.1
DHS-16 GeneProduct wormbase:WBGene00000979
DAF-9 GeneProduct ensembl:WBGene00000905
HSD-1 Protein wormbase:Y6B3B.11

References

  1. Hormonal control of C. elegans dauer formation and life span by a Rieske-like oxygenase. Rottiers V, Motola DL, Gerisch B, Cummins CL, Nishiwaki K, Mangelsdorf DJ, et al. Dev Cell. 2006 Apr;10(4):473–82. PubMed Europe PMC Scholia
  2. The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity. Wollam J, Magomedova L, Magner DB, Shen Y, Rottiers V, Motola DL, et al. Aging Cell. 2011 Oct;10(5):879–84. PubMed Europe PMC Scholia