Cytoplasmic ribosomal proteins

Kdahlquist; WikiPathways Maintenance bot; Martijn Van Iersel; Kristina Hanspers; Christine Chichester; Alex Pico; Eric Weitz; Egon Willighagen

Cytoplasmic ribosomal proteins (WP477)

Homo sapiens

The contents of this pathway represents the ribosomal proteins involved in translation. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP477 CPTAC Assay Portal]

Authors

Kdahlquist , Martijn Van Iersel , Kristina Hanspers , Christine Chichester , Alex Pico , Eric Weitz , and Egon Willighagen

Activity

Discuss this pathway

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Cited In

The m6A(m)-independent role of FTO in regulating WNT signaling pathways (2022).
DNA methylation of ARHGAP30 is negatively associated with ARHGAP30 expression in lung adenocarcinoma, which reduces tumor immunity and is detrimental to patient survival (2021).
Transcriptomic changes in peripheral blood mononuclear cells with weight loss: systematic literature review and primary data synthesis (2021).
Hematopoietic stem-cell senescence and myocardial repair - Coronary artery disease genotype/phenotype analysis of post-MI myocardial regeneration response induced by CABG/CD133+ bone marrow hematopoietic stem cell treatment in RCT PERFECT Phase 3 (2020).
Skeletal muscle reprogramming by breast cancer regardless of treatment history or tumor molecular subtype (2020).
Long-term cardiovascular disorders in the STOX1 mouse model of preeclampsia (2019).
Tissue-specific pathway activities: A retrospective analysis in COVID-19 patients (2022).
Comparative proteomics analysis of decidua reveals altered RNA processing and impaired ribosome function in recurrent pregnancy loss (2024).
Non-dialyzable uremic toxins and renal tubular cell damage in CKD patients: a systems biology approach (2024).
Single-cell ‘omic profiles of human aortic endothelial cells in vitro and human atherosclerotic lesions ex vivo reveal heterogeneity of endothelial subtype and response to activating perturbations (2024).
Transcriptional Profiling of SARS-CoV-2-Infected Calu-3 Cells Reveals Immune-Related Signaling Pathways (2024).

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Organisms

Homo sapiens

Communities

ONTOX Serious Request 2024 - MetaKids

Annotations

Pathway Ontology

ribosome biogenesis pathway

Participants

Query Drugst.One

Label	Type	Compact URI	Comment
Small (40S) Subunit	GeneProduct	complexportal:CPX-5223
RPL34	GeneProduct	ncbigene:6164
RPL4	GeneProduct	ncbigene:6124	also known as L1e. No E. coli homologue
RPS14	GeneProduct	ncbigene:6208	E. coli S11
RPL15	GeneProduct	ncbigene:6138
RPL35A	GeneProduct	ncbigene:6165
RPS13	GeneProduct	ncbigene:6207	E. coli S15
RPL7A	GeneProduct	ncbigene:6130
RPS9	GeneProduct	ncbigene:6203	E. coli S4
RPS4Y1	GeneProduct	ncbigene:6192	No E. coli homologue
RPL10A	GeneProduct	ncbigene:4736	E. coli L1
RPL32	GeneProduct	ncbigene:6161	Also known as S22e.
RPL37A	GeneProduct	ncbigene:6168
RPS10	GeneProduct	ncbigene:6204	No E. coli homologue
FAU	GeneProduct	ncbigene:2197	No E. coli homologue
RPL21	GeneProduct	ncbigene:6144
RPL17	GeneProduct	ncbigene:6139	E. coli L22
RPL29	GeneProduct	ncbigene:6159
RPL8	GeneProduct	ncbigene:6132	E. coli L2
RPL7	GeneProduct	ncbigene:6129	E. coli L30
RPS3A	GeneProduct	ncbigene:6189	No E. coli homologue
RPSA	GeneProduct	ncbigene:3921	E. coli S2
RPL3	GeneProduct	ncbigene:6122	E. coli L3
RPS7	GeneProduct	ncbigene:6201	No E. coli homologue
RPS23	GeneProduct	ncbigene:6228	E. coli S12
RPL23A	GeneProduct	ncbigene:6147	E. coli L23
RPL23	GeneProduct	ncbigene:9349	E. coli L14
RPL11	GeneProduct	ncbigene:6135	E. coli L5
RPL38	GeneProduct	ncbigene:6169
RPL18A	GeneProduct	ncbigene:6142
RPS26	GeneProduct	ncbigene:6231	No E. coli homologue
RPS15	GeneProduct	ncbigene:6209	E. coli S19
RPS25	GeneProduct	ncbigene:6230	No E. coli homologue
RPL19	GeneProduct	ncbigene:6143
RPL13	GeneProduct	ncbigene:6137
RPL6	GeneProduct	ncbigene:6128
RPS27	GeneProduct	ncbigene:6232	No E. coli homologue
RPS15A	GeneProduct	ncbigene:6210	E. coli S8
RPL14	GeneProduct	ncbigene:9045
RPS6KA6	GeneProduct	ncbigene:27330
RPS3	GeneProduct	ncbigene:6188	E. coli S3
RPL22	GeneProduct	ncbigene:6146
RPS6KA2	GeneProduct	ncbigene:6196
RPS16	GeneProduct	ncbigene:6217	E. coli S9
RPS2	GeneProduct	ncbigene:6187	E. coli S5
RPS6KA1	GeneProduct	ncbigene:6195
RPL24	GeneProduct	ncbigene:6152
RPL35	GeneProduct	ncbigene:11224	E. coli L29
RPL36A	GeneProduct	ncbigene:6173
RPS6KA3	GeneProduct	ncbigene:6197
RPL37	GeneProduct	ncbigene:6167
RPS8	GeneProduct	ncbigene:6202	No E. coli homologue
RPS6	GeneProduct	ncbigene:6194	No E. coli homologue
RPL36	GeneProduct	ncbigene:25873
RPL5	GeneProduct	ncbigene:6125	E. coli L18
RPS21	GeneProduct	ncbigene:6227	No E. coli homologue
RPL18	GeneProduct	ncbigene:6141
UBA52	GeneProduct	ncbigene:7311
RPL41	GeneProduct	ncbigene:6171
RPL27	GeneProduct	ncbigene:6155
RPS28	GeneProduct	ncbigene:6234	No E. coli homologue
RPL9	GeneProduct	ncbigene:6133	E. coli L6
MRPL19	GeneProduct	ncbigene:9801	E. coli L19
RPS29	GeneProduct	ncbigene:6235	E. coli S14
RPL28	GeneProduct	ncbigene:6158
RPS12	GeneProduct	ncbigene:6206	No E. coli homologue
RPS18	GeneProduct	ncbigene:6222	E. coli S13
RPS24	GeneProduct	ncbigene:6229	Also known as L33e. No E. coli homologue.
RPS19	GeneProduct	ncbigene:6223	No E. coli homologue
RPL31	GeneProduct	ncbigene:6160
RPL30	GeneProduct	ncbigene:6156	Also known as L25e.
RPL39	GeneProduct	ncbigene:6170
RPL26	GeneProduct	ncbigene:6154	E. coli L24
RPLP0	GeneProduct	ncbigene:6175	E. coli L10.
RPL10	GeneProduct	ncbigene:6134
RPS4X	GeneProduct	ncbigene:6191	No E. coli homologue
RPL12	GeneProduct	ncbigene:6136	Also known as L16e. E. coli L11.
RPS20	GeneProduct	ncbigene:6224	E. coli S10
RPS5	GeneProduct	ncbigene:6193	E. coli S7
RPS27A	GeneProduct	ncbigene:6233	No E. coli homologue
RPS17	GeneProduct	ncbigene:6218	No E. coli homologue
RPL27A	GeneProduct	ncbigene:6157	E. coli L15
RPLP1	GeneProduct	ncbigene:6176	E. coli L7/L12
RPL13A	GeneProduct	ncbigene:23521	E. coli L13
RPL3L	GeneProduct	ncbigene:6123
RPLP2	GeneProduct	ncbigene:6181	E. coli L7/L12
RPS11	GeneProduct	ncbigene:6205	E. coli S17
RPS6KB2	GeneProduct	ncbigene:6199
RPS6KB1	GeneProduct	ncbigene:6198

References

The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. Yoshihama M, Uechi T, Asakawa S, Kawasaki K, Kato S, Higa S, et al. Genome Res. 2002 Mar;12(3):379–90. PubMed Europe PMC Scholia

Cytoplasmic ribosomal proteins (WP477)

Homo sapiens

Authors

Activity

Discuss this pathway

Cited In

Organisms

Communities

Annotations

Pathway Ontology

Participants Query Drugst.One

References

Participants

Query Drugst.One