HIF1A and PPARG regulation of glycolysis (WP2456)

Homo sapiens

Hypoxia-inducible factor 1A and peroxisome proliferator activated receptor gamma play a role in regulating glycolysis. This pathway is part the [https://assays.cancer.gov/available_assays?wp_id=WP2456 CPTAC Assay Portal].

Authors

M Aguirre , Jonathan Mélius , Chris Evelo , Kristina Hanspers , Friederike Ehrhart , Alex Pico , and Finterly Hu

Activity

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Organisms

Homo sapiens

Communities

Annotations

Pathway Ontology

regulatory pathway glycolysis/gluconeogenesis pathway

Participants

Label Type Compact URI Comment
Glyceraldehyde-3-phosphate Metabolite kegg.compound:C00118
Pyruvate Metabolite kegg.compound:C00022
Fructose-1,6-biphosphate Metabolite kegg.compound:C05378
Dihydroxyacetonephosphate Metabolite kegg.compound:C00111
Lactate Metabolite kegg.compound:C00186
Glycerol-3-phosphate Metabolite kegg.compound:C00093
Lysophosphatidate Metabolite kegg.compound:C00681
Triacylglycerol Metabolite kegg.compound:C00422
Diacylglycerol Metabolite kegg.compound:C00165
Glucose Metabolite kegg.compound:C00031
GAPDH GeneProduct ensembl:ENSG00000111640
LDHA GeneProduct ensembl:ENSG00000134333
TPI1 GeneProduct ensembl:ENSG00000111669
GPD1 GeneProduct ensembl:ENSG00000167588
GPAT3 GeneProduct ensembl:ENSG00000138678
SLC2A1 GeneProduct ensembl:ENSG00000117394
PPARG GeneProduct ensembl:ENSG00000132170
HIF1A GeneProduct ensembl:ENSG00000100644
HIF1A GeneProduct ensembl:ENSG00000100644

References