Gastric cancer network 1 (WP2361)
Homo sapiens
Network generated by mapping candidate oncogenes and tumor suppressor genes identified by integrated analysis of expression array and aCGH data. Networks generated by Ingenuity Pathway Analysis. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP2361 CPTAC Assay Portal]
Authors
Kristina Hanspers , Martina Summer-Kutmon , Zahra Roudbari , Alex Pico , Egon Willighagen , Friederike Ehrhart , and Eric WeitzActivity
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Cited In
- Identification of CCNB2 as A Potential Non-Invasive Breast Cancer Biomarker in Peripheral Blood Mononuclear Cells Using The Systems Biology Approach (2021).
- A novel single-cell based method for breast cancer prognosis (2020).
- Proteostasis regulators modulate proteasomal activity and gene expression to attenuate multiple phenotypes in Fabry disease (2020).
- 24h-gene variation effect of combined bevacizumab/erlotinib in advanced non-squamous non-small cell lung cancer using exon array blood profiling (2017).
- Investigation of the relationship between COVID-19 and pancreatic cancer using bioinformatics and systems biology approaches (2024).
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Organisms
Homo sapiensCommunities
Annotations
Pathway Ontology
cell cycle pathway, mitotic cancer pathwayDisease Ontology
gastric adenocarcinoma stomach cancer| Label | Type | Compact URI | Comment |
|---|---|---|---|
| KIF15 | GeneProduct | ncbigene:56992 | |
| ESM1 | GeneProduct | ncbigene:11082 | |
| NOTCH1 | GeneProduct | ncbigene:4851 | |
| C21ORF33 | GeneProduct | ncbigene:8209 | |
| AURKA | GeneProduct | ncbigene:6790 | |
| MYBL2 | GeneProduct | ncbigene:4605 | |
| LIN9 | GeneProduct | ncbigene:286826 | |
| Cyclin A | GeneProduct | ncbigene:8900 | |
| CENPF | GeneProduct | ncbigene:1063 | |
| NUP107 | GeneProduct | ncbigene:57122 | |
| SMOC2 | GeneProduct | ncbigene:64094 | |
| Histone H3 | GeneProduct | ncbigene:3020 | |
| MCM4 | GeneProduct | ncbigene:4173 | |
| Histone H4 | GeneProduct | ncbigene:121504 | |
| KIF20B | GeneProduct | ncbigene:9585 | |
| APC | GeneProduct | ncbigene:324 | |
| UBE2C | GeneProduct | ncbigene:11065 | |
| RNF216 | GeneProduct | ncbigene:54476 | |
| S100P | GeneProduct | ncbigene:6286 | |
| E2F7 | GeneProduct | ncbigene:144455 | |
| ECT2 | GeneProduct | ncbigene:1894 | |
| TOP2A | GeneProduct | ncbigene:7153 | |
| ERVK6 | GeneProduct | ncbigene:64006 | |
| INO80D | GeneProduct | ncbigene:54891 | |
| RUVBL1 | GeneProduct | ncbigene:8607 | |
| ACTL6A | GeneProduct | ncbigene:86 | |
| GATS | GeneProduct | ncbigene:352954 | |
| TPX2 | GeneProduct | ncbigene:22974 | |
| CEP192 | GeneProduct | ncbigene:55125 |
References
- Integration of DNA copy number alterations and transcriptional expression analysis in human gastric cancer. Fan B, Dachrut S, Coral H, Yuen ST, Chu KM, Law S, et al. PLoS One. 2012;7(4):e29824. PubMed Europe PMC Scholia