Serotonin receptor 4/6/7 and NR3C signaling (WP3272)
Bos taurus
This pathway depicts the downstream signaling of serotonin via receptors 4, 6, and 7, resulting in the activation of EGR1 and NR3C1.
Authors
Martina Summer-Kutmon , Egon Willighagen , Eric Weitz , and Alex PicoActivity
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Organisms
Bos taurusCommunities
Annotations
Cell Type Ontology
neuronPathway Ontology
serotonin signaling pathwayLabel | Type | Compact URI | Comment |
---|---|---|---|
Cyclic AMP | Metabolite | cas:60-92-4 | |
serotonin | Metabolite | cas:50-67-9 | |
BRAF | GeneProduct | ensembl:ENSBTAG00000021761 | v-raf murine sarcoma viral oncogene homolog B1HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:673 |
HTR7 | GeneProduct | ensembl:ENSBTAG00000008783 | 5-hydroxytryptamine (serotonin) receptor 7HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3363 |
SRF | GeneProduct | ensembl:ENSBTAG00000012777 | serum response factorHomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6722 |
ELK4 | GeneProduct | ensembl:ENSBTAG00000004953 | ETS domain-containing protein Elk-4 (SRF accessory protein 1)HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2005 |
EGR1 | GeneProduct | ensembl:ENSBTAG00000010069 | early growth response proteinHomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1958 |
HTR6 | GeneProduct | ensembl:ENSBTAG00000007996 | 5-hydroxytryptamine (serotonin) receptor 6HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3362 |
GNAS | GeneProduct | ensembl:ENSBTAG00000017475 | GNAS (guanine nucleotide binding protein, alpha stimulating)HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2778 |
ATF1 | GeneProduct | ensembl:ENSBTAG00000018131 | activating transcription factor 1HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:466 |
MAP2K2 | GeneProduct | ensembl:ENSBTAG00000024450 | mitogen activated protein kinase kinase 2HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5605 |
MAPK3 | GeneProduct | ensembl:ENSBTAG00000016156 | mitogen activated protein kinase 3HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5595 |
CREB1 | GeneProduct | ensembl:ENSBTAG00000005474 | cAMP response element-binding protein 1HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1385 |
MAPK1 | GeneProduct | ensembl:ENSBTAG00000010312 | mitogen activated protein kinase 1HomologyConvert: Homo sapiens to Bos taurus: Original ID = H:MAPK1 |
MAP2K1 | GeneProduct | ensembl:ENSBTAG00000033983 | mitogen activated protein kinase kinase 1HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5604 |
RPS6KA5 | GeneProduct | ensembl:ENSBTAG00000010906 | ribosomal protein S6 kinase, polypeptide 5HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9252 |
GR-A | GeneProduct | ensembl:ENSBTAG00000019472 | nuclear receptor, subfamily 3, group C, member 1HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2908 |
RAP1A | GeneProduct | ensembl:ENSBTAG00000014710 | RAS-related protein-1aHomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5906 |
MAPKAPK2 | GeneProduct | ensembl:ENSBTAG00000038107 | MAP kinase-activated protein kinase 2HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9261 |
ELK1 | GeneProduct | ensembl:ENSBTAG00000015817 | ELK1, member of ETS oncogene familyHomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2002 |
HTR4 | GeneProduct | ensembl:ENSBTAG00000010837 | 5 hydroxytryptamine (serotonin) receptor 4HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3360 |
References
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