Fatty acid biosynthesis (WP504)
Rattus norvegicus
The production of fatty acids from acetyl-CoA and NADPH through the use of enzymes known as fatty acid synthases is referred to as fatty acid synthesis. This biological process occurs within the cytoplasm of cells. The majority of acetyl-CoA that is transformed into fatty acids originates from carbohydrates through the glycolytic pathway.
Authors
Kdahlquist , Zhouyf , Thomas Kelder , Chris Evelo , Susan Coort , Christine Chichester , Martina Summer-Kutmon , Egon Willighagen , Eric Weitz , and Alex PicoActivity
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Organisms
Rattus norvegicusCommunities
Annotations
Pathway Ontology
fatty acid biosynthetic pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| Palmitic acid | Metabolite | hmdb:HMDB0000220 | |
| beta-hydroxybutyryl | Metabolite | pubchem.compound:644065 | |
| Citric acid | Metabolite | hmdb:HMDB0000094 | |
| Crotonoyl-CoA | Metabolite | hmdb:HMDB0002009 | |
| Palmityl-CoA | Metabolite | hmdb:HMDB0001338 | |
| Butyryl-CoA | Metabolite | hmdb:HMDB0001088 | |
| Acetyl-CoA | Metabolite | hmdb:HMDB0001206 | |
| Malonyl-CoA | Metabolite | hmdb:HMDB0001175 | |
| Pyruvic acid | Metabolite | hmdb:HMDB0000243 | |
| Oxalacetic acid | Metabolite | hmdb:HMDB0000223 | |
| Acsl1 | GeneProduct | ncbigene:25288 | |
| Ech1 | GeneProduct | ncbigene:51798 | |
| Echdc2 | GeneProduct | ncbigene:298381 | |
| Fasn | GeneProduct | ncbigene:50671 | |
| Echdc3 | GeneProduct | ensembl:ENSRNOG00000048114 | |
| Acacb | GeneProduct | ncbigene:116719 | |
| Acaca | GeneProduct | ensembl:ENSRNOG00000034013 | |
| Acsl3 | GeneProduct | ncbigene:114024 | |
| Echs1 | GeneProduct | ncbigene:140547 | |
| Scd1 | GeneProduct | ncbigene:246074 | |
| Acly | GeneProduct | ncbigene:24159 | |
| Mecr | GeneProduct | ncbigene:29470 | |
| Acsl4 | GeneProduct | ncbigene:113976 | |
| Acsl5 | GeneProduct | ncbigene:94340 | |
| Hadhsc | GeneProduct | ncbigene:113965 | |
| Echdc1 | GeneProduct | ncbigene:361465 | |
| Acsl6 | GeneProduct | ncbigene:117243 | |
| Acas2 | GeneProduct | ncbigene:311569 | |
| Pc | GeneProduct | ncbigene:25104 | |
| Pecr | GeneProduct | ncbigene:113956 | |
| Decr1 | GeneProduct | ncbigene:117543 | |
| Acaa2 | GeneProduct | ncbigene:170465 |