Iron homeostasis (WP1596)

Mus musculus

Open in new tab Open in Newt (SBGN)
Download PNG Download SVG Download JSON Download GPML Learn more about Downloads
Iron is nessisary for all mammalian cells but is also toxic in excess. This pathway shows the regulation of iron between a cell and the blood stream.

Authors

Martijn Van Iersel , Kristina Hanspers , Samuel Sklar , Egon Willighagen , Daniela Digles , Martina Summer-Kutmon , and Eric Weitz

Activity

last edited

Discuss this pathway

Check for ongoing discussions or start your own.

Cited In

Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.

Organisms

Mus musculus

Communities

Annotations

Pathway Ontology

iron homeostasis pathway

Participants

Label Type Compact URI Comment
Iron Metabolite hmdb:HMDB0000692
Transferrin GeneProduct ensembl:ENSMUSG00000032554
Fth1 GeneProduct ncbigene:14319
Trfr2 GeneProduct ensembl:ENSMUSG00000029716
Ftl1 GeneProduct ensembl:ENSMUSG00000050708
hepcidin-2 GeneProduct ensembl:ENSMUSG00000056978
Ireb2 GeneProduct ensembl:ENSMUSG00000032293
hepcidin GeneProduct ensembl:ENSMUSG00000050440
Tnf GeneProduct ensembl:ENSMUSG00000024401
IL-6 GeneProduct ensembl:ENSMUSG00000025746
hemojuvelin GeneProduct ensembl:ENSMUSG00000038403
Hfe GeneProduct ensembl:ENSMUSG00000006611
IL6R GeneProduct ensembl:ENSMUSG00000027947
Ferroportin GeneProduct ensembl:ENSMUSG00000025993
IL-1 GeneProduct ensembl:ENSMUSG00000027399

References