Methylerythritol phosphate pathway (WP2212)
Oryza sativa
In plants, the 2-C-methyl-d-erythritol 4-phosphate (MEP) pathway located in the plastids provides precursors for the isoprenoid hormones, monoterpenes, carotenoids and chlorophyll side chains, prenylquinones and tocopherol biosynthesis.
Authors
Pankaj Jaiswal , Egon Willighagen , Martina Summer-Kutmon , and Denise SlenterActivity
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Cited In
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Organisms
Oryza sativaCommunities
Annotations
Cell Type Ontology
obsolete plant cellPathway Ontology
tetrahydrobiopterin metabolic pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| 1-deoxy-D-xylulose 5-phosphate | Metabolite | kegg.compound:C11437 | |
| NADPH | Metabolite | cas:53-57-6 | |
| ADP | Metabolite | cas:58-64-0 | |
| ATP | Metabolite | cas:56-65-5 | |
| 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol | Metabolite | chebi:16840 | |
| 2-C-methyl-D-erythritol-4-phosphate | Metabolite | kegg.compound:C11434 | |
| CTP | Metabolite | cas:65-47-4 | |
| pyruvate | Metabolite | cas:127-17-3 | |
| H2O | Metabolite | cas:7732-18-5 | |
| diphosphate | Metabolite | cas:2466-09-3 | |
| Δ3-isopentenyl-PP | Metabolite | kegg.compound:C00129 | |
| NADP+ | Metabolite | cas:53-59-8 | |
| dimethylallyl-PP | Metabolite | cas:358-71-4 | |
| 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate | Metabolite | kegg.compound:C11811 | |
| 2-C-methyl-D-erythritol-2,4-cyclodiphosphate | Metabolite | kegg.compound:C11453 | |
| CO2 | Metabolite | cas:124-38-9 | |
| CMP | Metabolite | cas:63-37-6 | |
| 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol | Metabolite | kegg.compound:C11435 | |
| D-glyceraldehyde-3-phosphate | Metabolite | cas:591-57-1 | |
| NAD(P)+ | Metabolite | cas:53-59-8 | |
| NAD(P)H | Metabolite | chebi:13392 | |
| H+ | Metabolite | cas:12408-02-5 | |
| EC:1.17.1.2 | GeneProduct | eccode:1.17.1.2 | |
| LOC_Os07g36190 | GeneProduct | :LOC_Os07g36190 | hydrolase, NUDIX family, domain containing protein, expressed//isopentenyl-diphosphate delta-isomerase |
| LOC_Os05g33840 | GeneProduct | :LOC_Os05g33840 | transketolase, putative, expressed//terpenoid biosynthetic process//1-deoxy-D-xylulose-5-phosphate synthase//transketolase |
| EC:2.2.1.7 | GeneProduct | eccode:2.2.1.7 | |
| LOC_Os01g66360 | GeneProduct | :LOC_Os01g66360 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, putative, expressed//terpenoid biosynthetic process//4-diphosphocytidyl-2C-methyl-D-erythritol synthase |
| EC:5.3.3.2 | GeneProduct | eccode:5.3.3.2 | |
| LOC_Os02g45660 | GeneProduct | :LOC_Os02g45660 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, chloroplast precursor, putative, expressed//terpenoid biosynthetic process//2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase |
| EC:1.17.4.3 | GeneProduct | eccode:1.17.4.3 | |
| LOC_Os03g52170 | GeneProduct | :LOC_Os03g52170 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, putative, expressed//terpenoid biosynthetic process |
| LOC_Os01g01710 | GeneProduct | :LOC_Os01g01710 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplast precursor, putative, expressed//isoprenoid biosynthetic process//catalytic activity//1-deoxy-D-xylulose-5-phosphate reductoisomerase |
| LOC_Os07g40260 | GeneProduct | :LOC_Os07g40260 | eukaryotic aspartyl protease domain containing protein, expressed |
| EC:1.1.1.267 | GeneProduct | eccode:1.1.1.267 | |
| EC:2.7.1.148 | GeneProduct | eccode:2.7.1.148 | |
| LOC_Os02g39160 | GeneProduct | :LOC_Os02g39160 | hydroxymethylbutenyl 4-diphosphate synthase, putative, expressed//terpenoid biosynthetic process//sugar:hydrogen symporter activity//phosphoenolpyruvate-dependent sugar phosphotransferase system//4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase |
| LOC_Os05g34180 | GeneProduct | :LOC_Os05g34180 | hydrolase, NUDIX family, domain containing protein, expressed//isoprenoid biosynthetic process//terpenoid biosynthetic process//isopentenyl-diphosphate delta-isomerase |
| LOC_Os07g09190 | GeneProduct | :LOC_Os07g09190 | transketolase, putative, expressed//terpenoid biosynthetic process |
| EC:2.7.7.60 | GeneProduct | eccode:2.7.7.60 | |
| EC:4.6.1.12 | GeneProduct | eccode:4.6.1.12 | |
| LOC_Os06g05100 | GeneProduct | :LOC_Os06g05100 | transketolase, putative, expressed//terpenoid biosynthetic process//1-deoxy-D-xylulose-5-phosphate synthase |
| LOC_Os01g58790 | GeneProduct | :LOC_Os01g58790 | GHMP kinases ATP-binding protein, putative, expressed//ATP binding//terpenoid biosynthetic process//4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase |