NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde (WP84)

Saccharomyces cerevisiae

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This is the later portion of the pathway used in eukaryotes for de novo biosynthesis of NAD, which starts with the amino acid L-tryptophan. Description from https://pathway.yeastgenome.org/.

Authors

Meredith Braymer , Egon Willighagen , Daniela Digles , Eric Weitz , and Kristina Hanspers

Activity

last edited

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Organisms

Saccharomyces cerevisiae

Communities

Annotations

Pathway Ontology

nicotinamide adenine dinucleotide biosynthetic pathway classic metabolic pathway

Participants

Label Type Compact URI Comment
H+ Metabolite chebi:15378
ATP Metabolite cas:1927-31-7
nicotinate adenine dinucleotide Metabolite chebi:58437
diphosphate Metabolite cas:2466-09-3
2-amino-3-carboxymuconate-6-semialdehyde Metabolite chebi:994
L-glutamate Metabolite cas:56-86-0
quinolinate Metabolite hmdb:HMDB00232
H2O Metabolite chebi:15377
AMP Metabolite chebi:456215
L-glutamine Metabolite cas:56-85-9
NAD+ Metabolite chebi:57540
β-nicotinate D-ribonucleotide Metabolite chebi:57502
NMA2 GeneProduct sgd:S000003242
NMA1 GeneProduct sgd:S000004320
QNS1 GeneProduct sgd:S000001116
BNA6 GeneProduct sgd:S000001943

References

  1. URL: https://pathway.yeastgenome.org/YEAST/NEW-IMAGE?type=PATHWAY&object=PWY-5653