Fatty acid biosynthesis (WP38)
Caenorhabditis elegans
The fatty acid synthesis of the roundworm C. Elegans is a highly conserved pathway evolutionary. This pathways is therefore of great importance to understand fat synthesis and nutrient sensing in adiposity regulation, which is key to understand the molecular mechanism behind obesity.
Authors
Kdahlquist , Chris Evelo , Egon Willighagen , Christine Chichester , Lauren J. Dupuis , Eric Weitz , Friederike Ehrhart , Denise Slenter , and Alex PicoActivity
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Organisms
Caenorhabditis elegansCommunities
Lipids and LIPID MAPSAnnotations
Pathway Ontology
fatty acid biosynthetic pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| oxaloacetate | Metabolite | chebi:16452 | |
| 3-ketoacyl-CoA | Metabolite | chebi:57347 | |
| Acetyl-CoA | Metabolite | hmdb:HMDB01206 | |
| Malonyl-CoA | Metabolite | hmdb:HMDB01175 | |
| Palmitate | Metabolite | chebi:15756 | |
| pyruvate | Metabolite | chebi:15361 | |
| citrate | Metabolite | chebi:133748 | |
| C32E8.9 | GeneProduct | ncbigene:171951 | |
| F32H2.5 | GeneProduct | ncbigene:172715 | |
| acs-17 | GeneProduct | ncbigene:180859 | |
| F32H2.5 | GeneProduct | ncbigene:172715 | |
| F32H2.5 | GeneProduct | ncbigene:172715 | |
| Y25C1A.13 | GeneProduct | ncbigene:173657 | |
| F32H2.5 | GeneProduct | ncbigene:172715 | |
| Y65B4BL.5 | GeneProduct | ncbigene:171643 | |
| pyc-1 | GeneProduct | ncbigene:179616 | |
| F53C11.3 | GeneProduct | ncbigene:179872 | |
| ech-2 | GeneProduct | ncbigene:3564942 | |
| C36A4.9 | GeneProduct | ncbigene:175500 | |
| D1005.1 | GeneProduct | ncbigene:180485 | |
| fat-5 | GeneProduct | ncbigene:180162 | |
| W09H1.5 | GeneProduct | ncbigene:174963 | |
| F54C8.1 | GeneProduct | ncbigene:186222 | |
| F32H2.5 | GeneProduct | ncbigene:172715 | |
| ech-6 | GeneProduct | ncbigene:176376 | |
| F32H2.5 | GeneProduct | ncbigene:172715 | |
| F37C12.7 | GeneProduct | ncbigene:176005 | |
| F32H2.5 | GeneProduct | ncbigene:172715 | |
| Thiolases | GeneProduct | ncbigene:176756 | |
| F32H2.5 | GeneProduct | ncbigene:172715 |
References
- Fat synthesis and adiposity regulation in Caenorhabditis elegans. Watts JL. Trends Endocrinol Metab. 2009 Mar;20(2):58–65. PubMed Europe PMC Scholia