Aspirin and miRNAs (WP4707)

Homo sapiens

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Aspirin effects on miRNAs.

Authors

Aminkhazeeitabari , Friederike Ehrhart , Lauren J. Dupuis , Egon Willighagen , Kristina Hanspers , and Eric Weitz

Activity

last edited

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Organisms

Homo sapiens

Communities

Annotations

Pathway Ontology

microRNA pathway acetylsalicylic acid drug pathway

Participants
Query Drugst.One

Label Type Compact URI Comment
Acetylsalicylic acid Metabolite chebi:15365 Aspirin
PPARA GeneProduct ensembl:ENSG00000186951
ABCC4 GeneProduct ensembl:ENSG00000125257 MRP4
VEGFA GeneProduct ensembl:ENSG00000112715
MVD GeneProduct ncbigene:4597
PDK1 GeneProduct ensembl:ENSG00000152256
PTGS2 GeneProduct ensembl:ENSG00000073756 COX-2
WNT1 GeneProduct ensembl:ENSG00000125084
PTGS1 GeneProduct ensembl:ENSG00000095303 COX-1
NFKB1 GeneProduct ensembl:ENSG00000109320
NOS3 GeneProduct ensembl:ENSG00000164867 eNOS

References

  1. MicroRNA-21 regulates peroxisome proliferator-activated receptor alpha, a molecular mechanism of cardiac pathology in Cardiorenal Syndrome Type 4. Chuppa S, Liang M, Liu P, Liu Y, Casati MC, Cowley AW, et al. Kidney Int. 2018 Feb;93(2):375–89. PubMed Europe PMC Scholia