Serotonin HTR1 group and FOS pathway (WP722)

Homo sapiens

Authors

Ruke Achoja , Kristina Hanspers , Alex Pico , Thomas Kelder , Andra Waagmeester , Egon Willighagen , Friederike Ehrhart , Eric Weitz , and Denise Slenter

Activity

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Organisms

Homo sapiens

Communities

Annotations

Pathway Ontology

serotonin signaling pathway

References

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92. Protein kinase Cdelta mediates neurogenic but not mitogenic activation of mitogen-activated protein kinase in neuronal cells. Corbit KC, Foster DA, Rosner MR. Mol Cell Biol. 1999 Jun;19(6):4209–18. PubMed Europe PMC Scholia
93. Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase. Hetman M, Kanning K, Cavanaugh JE, Xia Z. J Biol Chem. 1999 Aug 6;274(32):22569–80. PubMed Europe PMC Scholia
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96. Effects of geldanamycin on signaling through activator-protein 1 in hypoxic HT29 human colon adenocarcinoma cells. Vasilevskaya IA, O’Dwyer PJ. Cancer Res. 1999 Aug 15;59(16):3935–40. PubMed Europe PMC Scholia
97. TNF-mediated activation of the stress-activated protein kinase pathway: TNF receptor-associated factor 2 recruits and activates germinal center kinase related. Shi CS, Leonardi A, Kyriakis J, Siebenlist U, Kehrl JH. J Immunol. 1999 Sep 15;163(6):3279–85. PubMed Europe PMC Scholia
98. The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism. Winzen R, Kracht M, Ritter B, Wilhelm A, Chen CY, Shyu AB, et al. EMBO J. 1999 Sep 15;18(18):4969–80. PubMed Europe PMC Scholia
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104. Gi-mediated translocation of GLUT4 is independent of p85/p110alpha and p110gamma phosphoinositide 3-kinases but might involve the activation of Akt kinase. Wang L, Hayashi H, Kishi K, Huang L, Hagi A, Tamaoka K, et al. Biochem J. 2000 Feb 1;345 Pt 3(Pt 3):543–55. PubMed Europe PMC Scholia
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106. Ischemic preconditioning activates MAPKAPK2 in the isolated rabbit heart: evidence for involvement of p38 MAPK. Nakano A, Baines CP, Kim SO, Pelech SL, Downey JM, Cohen MV, et al. Circ Res. 2000 Feb 4;86(2):144–51. PubMed Europe PMC Scholia
107. Deficiency of the stress kinase p38alpha results in embryonic lethality: characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells. Allen M, Svensson L, Roach M, Hambor J, McNeish J, Gabel CA. J Exp Med. 2000 Mar 6;191(5):859–70. PubMed Europe PMC Scholia
108. Role of mitogen-activated protein kinase cascades in mediating lipopolysaccharide-stimulated induction of cyclooxygenase-2 and IL-1 beta in RAW264 macrophages. Caivano M, Cohen P. J Immunol. 2000 Mar 15;164(6):3018–25. PubMed Europe PMC Scholia
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128. Phorbol ester-induced expression of airway squamous cell differentiation marker, SPRR1B, is regulated by protein kinase Cdelta /Ras/MEKK1/MKK1-dependent/AP-1 signal transduction pathway. Vuong H, Patterson T, Shapiro P, Kalvakolanu DV, Wu R, Ma WY, et al. J Biol Chem. 2000 Oct 13;275(41):32250–9. PubMed Europe PMC Scholia
129. cAMP response element-binding protein-binding protein mediates thyrotropin-releasing hormone signaling on thyrotropin subunit genes. Hashimoto K, Zanger K, Hollenberg AN, Cohen LE, Radovick S, Wondisford FE. J Biol Chem. 2000 Oct 27;275(43):33365–72. PubMed Europe PMC Scholia
130. The cJun N-terminal kinase (JNK) signaling pathway mediates induction of urokinase-type plasminogen activator (uPA) by the alkylating agent MNNG. Parra M, Lluís F, Miralles F, Caelles C, Muñoz-Cánoves P. Blood. 2000 Aug 15;96(4):1415–24. PubMed Europe PMC Scholia
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132. Effect of extracellular signal-regulated kinase on p53 accumulation in response to cisplatin. Persons DL, Yazlovitskaya EM, Pelling JC. J Biol Chem. 2000 Nov 17;275(46):35778–85. PubMed Europe PMC Scholia
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134. Distinct roles of the adaptor protein Shc and focal adhesion kinase in integrin signaling to ERK. Barberis L, Wary KK, Fiucci G, Liu F, Hirsch E, Brancaccio M, et al. J Biol Chem. 2000 Nov 24;275(47):36532–40. PubMed Europe PMC Scholia
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138. Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601. Zhang BH, Guan KL. EMBO J. 2000 Oct 16;19(20):5429–39. PubMed Europe PMC Scholia
139. Protein kinase C zeta plays a central role in activation of the p42/44 mitogen-activated protein kinase by endotoxin in alveolar macrophages. Monick MM, Carter AB, Flaherty DM, Peterson MW, Hunninghake GW. J Immunol. 2000 Oct 15;165(8):4632–9. PubMed Europe PMC Scholia
140. MEK inhibition enhances paclitaxel-induced tumor apoptosis. MacKeigan JP, Collins TS, Ting JP. J Biol Chem. 2000 Dec 15;275(50):38953–6. PubMed Europe PMC Scholia
141. Intracellular calcium mobilization induces immediate early gene pip92 via Src and mitogen-activated protein kinase in immortalized hippocampal cells. Chung KC, Sung JY, Ahn W, Rhim H, Oh TH, Lee MG, et al. J Biol Chem. 2001 Jan 19;276(3):2132–8. PubMed Europe PMC Scholia
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143. A 14-3-3 mRNA is up-regulated in amyotrophic lateral sclerosis spinal cord. Malaspina A, Kaushik N, de Belleroche J. J Neurochem. 2000 Dec;75(6):2511–20. PubMed Europe PMC Scholia
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146. Stimulation of extracellular signal-regulated kinases and proliferation in rat osteoblastic cells by parathyroid hormone is protein kinase C-dependent. Swarthout JT, Doggett TA, Lemker JL, Partridge NC. J Biol Chem. 2001 Mar 9;276(10):7586–92. PubMed Europe PMC Scholia
147. Evidence for protein kinase C-dependent and -independent activation of mitogen-activated protein kinase in T cells: potential role of additional diacylglycerol binding proteins. Puente LG, Stone JC, Ostergaard HL. J Immunol. 2000 Dec 15;165(12):6865–71. PubMed Europe PMC Scholia
148. Role of p38 MAP kinase in endothelial cell alignment induced by fluid shear stress. Azuma N, Akasaka N, Kito H, Ikeda M, Gahtan V, Sasajima T, et al. Am J Physiol Heart Circ Physiol. 2001 Jan;280(1):H189-97. PubMed Europe PMC Scholia
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150. The information content of spontaneous retinal waves. Butts DA, Rokhsar DS. J Neurosci. 2001 Feb 1;21(3):961–73. PubMed Europe PMC Scholia
151. Cell-cycle-dependent activation of mitogen-activated protein kinase kinase (MEK-1/2) in myeloid leukemia cell lines and induction of growth inhibition and apoptosis by inhibitors of RAS signaling. Morgan MA, Dolp O, Reuter CW. Blood. 2001 Mar 15;97(6):1823–34. PubMed Europe PMC Scholia
152. Inhibition of extracellular signal-regulated kinase (ERK) mediates cell cycle phase independent apoptosis in vinblastine-treated ML-1 cells. Stadheim TA, Xiao H, Eastman A. Cancer Res. 2001 Feb 15;61(4):1533–40. PubMed Europe PMC Scholia
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156. Regulation of Stat3 activation by MEK kinase 1. Lim CP, Cao X. J Biol Chem. 2001 Jun 15;276(24):21004–11. PubMed Europe PMC Scholia
157. Basic fibroblast growth factor-induced activation of novel CREB kinase during the differentiation of immortalized hippocampal cells. Sung JY, Shin SW, Ahn YS, Chung KC. J Biol Chem. 2001 Apr 27;276(17):13858–66. PubMed Europe PMC Scholia
158. Thrombopoietin-mediated sustained activation of extracellular signal-regulated kinase in UT7-Mpl cells requires both Ras-Raf-1- and Rap1-B-Raf-dependent pathways. Garcia J, de Gunzburg J, Eychène A, Gisselbrecht S, Porteu F. Mol Cell Biol. 2001 Apr;21(8):2659–70. PubMed Europe PMC Scholia
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160. Constitutive ERK1/2 activation in esophagogastric rib bone marrow micrometastatic cells is MEK-independent. Barry OP, Mullan B, Sheehan D, Kazanietz MG, Shanahan F, Collins JK, et al. J Biol Chem. 2001 May 4;276(18):15537–46. PubMed Europe PMC Scholia
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163. Mitogen-activated protein kinase kinase 4 metastasis suppressor gene expression is inversely related to histological pattern in advancing human prostatic cancers. Kim HL, Vander Griend DJ, Yang X, Benson DA, Dubauskas Z, Yoshida BA, et al. Cancer Res. 2001 Apr 1;61(7):2833–7. PubMed Europe PMC Scholia
164. Increased expression of protein kinase Calpha, interleukin-1alpha, and RhoA guanosine 5’-triphosphatase in osteoblasts expressing the Ser252Trp fibroblast growth factor 2 receptor Apert mutation: identification by analysis of complementary DNA microarray. Lomri A, Lemonnier J, Delannoy P, Marie PJ. J Bone Miner Res. 2001 Apr;16(4):705–12. PubMed Europe PMC Scholia
165. Developmental regulation of mitogen-activated protein kinase-activated kinases-2 and -3 (MAPKAPK-2/-3) in vivo during corpus luteum formation in the rat. Maizels ET, Mukherjee A, Sithanandam G, Peters CA, Cottom J, Mayo KE, et al. Mol Endocrinol. 2001 May;15(5):716–33. PubMed Europe PMC Scholia
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170. The involvement of phosphoinositide 3-kinase (PI3-Kinase) and phospholipase C gamma (PLC gamma) pathway in the morphine-induced supraspinal antinociception in the mouse. Narita M, Ohnishi O, Nemoto M, Aoki T, Suzuki T. Nihon Shinkei Seishin Yakurigaku Zasshi. 2001 Feb;21(1):7–14. PubMed Europe PMC Scholia
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