NO/cGMP/PKG mediated neuroprotection (WP4008)

Homo sapiens

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NO/cGMP/PKG mediated Neuroprotection

Authors

Thorben Sauer , Egon Willighagen , Kristina Hanspers , Laurent Winckers , Eric Weitz , and Denise Slenter

Activity

last edited

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Cited In

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Organisms

Homo sapiens

Communities

Annotations

Cell Type Ontology

microglial cell neural cell neuron endothelial cell

Pathway Ontology

signaling pathway signaling pathway involving second messengers

Disease Ontology

dementia

Participants
Query Drugst.One

Label Type Compact URI Comment
Ca2+ Metabolite chebi:29108
NADP Metabolite chebi:18009
O2 Metabolite chebi:29372
GTP Metabolite chebi:37565
L-Arginine Metabolite chebi:16467
K+ Metabolite chebi:29103
L-Citrulline Metabolite chebi:16349
NO Metabolite chebi:16480
L-Glutamate Metabolite chebi:16015
NADPH Metabolite chebi:16474
cGMP Metabolite chebi:16356
TBH Metabolite chebi:64090
AMP Metabolite chebi:16027
Mg2+ Metabolite chebi:18420
LPS Metabolite chebi:89981
cAMP Metabolite chebi:17489
TSPO GeneProduct ensembl:ENSG00000100300
GRIN2D GeneProduct ensembl:ENSG00000105464
ACTN2 GeneProduct ensembl:ENSG00000077522
CNGB1 GeneProduct ensembl:ENSG00000070729
GUCY1B2 GeneProduct ensembl:ENSG00000123201
XIAP GeneProduct ensembl:ENSG00000101966
PDE3 GeneProduct ensembl:ENSG00000172572
CNGA3 GeneProduct ensembl:ENSG00000144191
GRIN2B GeneProduct ensembl:ENSG00000273079
CNGA2 GeneProduct ensembl:ENSG00000183862
CAMK2G GeneProduct ensembl:ENSG00000148660
GUCY1A2 GeneProduct ensembl:ENSG00000152402
GUCY1A3 GeneProduct ensembl:ENSG00000164116
eNOS GeneProduct ensembl:ENSG00000164867
CNGA1 GeneProduct ensembl:ENSG00000198515
NPR1 GeneProduct ensembl:ENSG00000169418
NFKB1 GeneProduct ensembl:ENSG00000109320
CNGB3 GeneProduct ensembl:ENSG00000170289
AKAP9 GeneProduct ensembl:ENSG00000127914
CASP9 GeneProduct ensembl:ENSG00000132906
BCL2 GeneProduct ensembl:ENSG00000171791
nNOS GeneProduct ensembl:ENSG00000089250
GUCY1B3 GeneProduct ensembl:ENSG00000061918
CAMK2B GeneProduct ensembl:ENSG00000058404
ANP GeneProduct ensembl:ENSG00000175206
NEFL GeneProduct ensembl:ENSG00000277586
PDE2 GeneProduct ensembl:ENSG00000186642
GRIN2A GeneProduct ensembl:ENSG00000183454
CALM1 GeneProduct ensembl:ENSG00000198668
CAMK2A GeneProduct ensembl:ENSG00000070808
Cytochrome C GeneProduct ensembl:ENSG00000172115
CAMK2D GeneProduct ensembl:ENSG00000145349
Cyclophilin D GeneProduct ensembl:ENSG00000171497
GRIN2C GeneProduct ensembl:ENSG00000161509
PKG2 GeneProduct ensembl:ENSG00000138669
GRIN1 GeneProduct ensembl:ENSG00000176884
CNGA4 GeneProduct ensembl:ENSG00000132259
NFKBIA GeneProduct ensembl:ENSG00000100906
NFKB3 GeneProduct ensembl:ENSG00000173039
CREB1 GeneProduct ensembl:ENSG00000118260
BNP GeneProduct ensembl:ENSG00000120937
DLG4 GeneProduct ensembl:ENSG00000132535
iNOS GeneProduct ensembl:ENSG00000007171
BAD GeneProduct ensembl:ENSG00000002330
IL-1B Protein ensembl:ENSG00000125538
TNF-a Protein ensembl:ENSG00000232810
IFN-Gamma Protein ensembl:ENSG00000111537

References