MAPK signaling pathway (WP510)
Saccharomyces cerevisiae
The MAPK/ERK pathway is a signal transduction pathway that couples intracellular responses to the binding of growth factors to cell surface receptors. In many cell types, activation of this pathway promotes cell division. Adapted from: http://www.genome.ad.jp/dbget-bin/get_pathway?org_name=sce&mapno=04010
Authors
Nathan Salomonis , Bruce Conklin , Ron Shigeta , Thomas Kelder , Michiel Adriaens , Daniela Digles , Egon Willighagen , Nuno , Kristina Hanspers , Alex Pico , Finterly Hu , and Eric WeitzActivity
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Organisms
Saccharomyces cerevisiaeCommunities
Annotations
Pathway Ontology
mitogen activated protein kinase signaling pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| GTP | Metabolite | cas:2564-35-4 | |
| GDP | Metabolite | cas:146-91-8 | |
| Ste4 | GeneProduct | sgd:S000005738 | |
| Ste1 | GeneProduct | sgd:S000001126 | |
| Mlp1 | GeneProduct | sgd:S000001803 | |
| Msg5 | GeneProduct | sgd:S000004998 | |
| Wsc1,2,3 | GeneProduct | sgd:S000005534 | |
| Ste7 | GeneProduct | sgd:S000002318 | |
| Ssk2 | GeneProduct | sgd:S000005314 | |
| Ras2 | GeneProduct | sgd:S000005042 | |
| Ste11 | GeneProduct | sgd:S000004354 | |
| Hog1 | GeneProduct | sgd:S000004103 | |
| Cdc42 | GeneProduct | sgd:S000004219 | |
| Sho1 | GeneProduct | sgd:S000000920 | |
| Ctt1 | GeneProduct | sgd:S000003320 | |
| Swi4 | GeneProduct | sgd:S000000913 | |
| Rho1 | GeneProduct | sgd:S000006369 | |
| Ste5 scaffold | GeneProduct | sgd:S000002510 | |
| Mkk1 | GeneProduct | sgd:S000005757 | |
| Ste20 | GeneProduct | sgd:S000000999 | |
| Fus1 | GeneProduct | sgd:S000000532 | |
| Ssk1 | GeneProduct | sgd:S000003996 | |
| Kss1 | GeneProduct | sgd:S000003272 | |
| Mid2 | GeneProduct | sgd:S000004324 | |
| Pkc1 | GeneProduct | sgd:S000000201 | |
| MATalpha | GeneProduct | sgd:S000006108 | |
| Cdc24 | GeneProduct | sgd:S000000039 | |
| Ste2 | GeneProduct | sgd:S000001868 | |
| Mcm1 | GeneProduct | sgd:S000004646 | |
| Fks2 | GeneProduct | sgd:S000003264 | |
| Bkc1 | GeneProduct | sgd:S000003631 | |
| Msn2 | GeneProduct | sgd:S000004640 | |
| Fks1 | GeneProduct | sgd:S000004334 | |
| Pbs2 | GeneProduct | sgd:S000003664 | |
| Dig1 | GeneProduct | sgd:S000005970 | |
| Sln1 | GeneProduct | sgd:S000001409 | |
| Ste12 | GeneProduct | sgd:S000001126 | |
| Ypd1 | GeneProduct | sgd:S000002394 | |
| Tec1 | GeneProduct | sgd:S000000287 | |
| Ste18 | GeneProduct | sgd:S000003846 | |
| Bem1 | GeneProduct | sgd:S000000404 | |
| Ste3 | GeneProduct | sgd:S000001661 | |
| Glo1 | GeneProduct | sgd:S000004463 | |
| GPA1 | GeneProduct | sgd:S000001047 | |
| Dig1,2 | GeneProduct | sgd:S000005970 | |
| MATa | GeneProduct | sgd:S000002869 | |
| Rlm1 | GeneProduct | sgd:S000006010 | |
| Bni1 | GeneProduct | sgd:S000005215 | |
| Slt2 | GeneProduct | sgd:S000001072 | |
| Far1 | GeneProduct | sgd:S000003693 |
References
- Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae. Chen RE, Thorner J. Biochim Biophys Acta. 2007 Aug;1773(8):1311–40. PubMed Europe PMC Scholia