Mitochondrial long chain fatty acid beta-oxidation (WP368)
Homo sapiens
Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP368 CPTAC Assay Portal]
Authors
Niradiz Reyes , Thomas Kelder , Kristina Hanspers , Jildau Bouwman , Martijn Van Iersel , Alex Pico , Egon Willighagen , Daniela Digles , Zahra Roudbari , Marianthi Kalafati , Martina Summer-Kutmon , Irene Hemel , and Eric WeitzActivity
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Cited In
- Human Monocytes Exposed to SARS-CoV-2 Display Features of Innate Immune Memory Producing High Levels of CXCL10 upon Restimulation (2023).
- New Insight Into Mechanisms of Hepatic Encephalopathy: An Integrative Analysis Approach to Identify Molecular Markers and Therapeutic Targets.
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Organisms
Homo sapiensCommunities
Annotations
Pathway Ontology
fatty acid beta degradation pathway fatty acid beta degradation pathway classic metabolic pathwayLabel | Type | Compact URI | Comment |
---|---|---|---|
Long chain Acyl-CoA | Metabolite | chebi:83139 | |
3-Ketoacyl-CoA | Metabolite | chebi:57347 | |
Acetyl-CoA | Metabolite | cas:72-89-9 | |
Long Chain Fatty Acid | Metabolite | chebi:15904 | |
trans-D2-Enoyl-CoA | Metabolite | chebi:10723 | |
Acyl-CoA (n-2) | Metabolite | chebi:17984 | |
ACSL4 | GeneProduct | ncbigene:2182 | |
SCP2 | GeneProduct | ncbigene:6342 | |
CPT2 | GeneProduct | ncbigene:1376 | |
EHHADH | GeneProduct | ncbigene:1962 | |
ACSL1 | GeneProduct | ncbigene:2180 | |
DCI | GeneProduct | ncbigene:1632 | |
ACADS | GeneProduct | ncbigene:35 | |
HADHA | GeneProduct | ncbigene:3030 | similiar to: ECHA RAT |
CPT1A | GeneProduct | ncbigene:1374 | |
ACSL2 | GeneProduct | ncbigene:80221 | |
ACSL3 | GeneProduct | ncbigene:2181 | |
ACADL | GeneProduct | ncbigene:33 | |
ACADM | GeneProduct | ncbigene:34 | |
ACADVL | GeneProduct | ncbigene:37 | |
HADHSC | GeneProduct | ncbigene:3033 | |
SLC25A20 | GeneProduct | ncbigene:788 | |
PECR | GeneProduct | ncbigene:55825 |