Glucose homeostasis (WP661)

Homo sapiens

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An organism-level overview of Glucose homeostasis. At this moment the focus is on metabolites that can be measured in the plasma, but it would be nice to show the interaction between the different organs (Adipose tissue, Liver, Intestine, Muscle) as well as the involvement of hormones other than insulin

Authors

Martijn Van Iersel , Kristina Hanspers , Alex Pico , Egon Willighagen , Martina Summer-Kutmon , and Eric Weitz

Activity

last edited

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Organisms

Homo sapiens

Communities

Annotations

Pathway Ontology

glucose homeostasis pathway

Participants
Query Drugst.One

Label Type Compact URI Comment
Glycerol Metabolite hmdb:HMDB0000131
Isoleucine Metabolite hmdb:HMDB0000172
Methionine Metabolite hmdb:HMDB0000696
GCA Metabolite hmdb:HMDB0000138
Glucose Metabolite hmdb:HMDB0000122
Ornithine Metabolite hmdb:HMDB0000214
Lactate Metabolite hmdb:HMDB0000190
Arginine Metabolite hmdb:HMDB0000517
Hypoxanthine Metabolite hmdb:HMDB0000157
Histidine Metabolite hmdb:HMDB0000177
B-OH-butyrate Metabolite hmdb:HMDB0000011
GCDCA Metabolite hmdb:HMDB0000637
Pyruvate Metabolite hmdb:HMDB0000243
TCDCA Metabolite hmdb:HMDB0000951
Malate Metabolite hmdb:HMDB0000156
Tyrosine Metabolite hmdb:HMDB0000158
Phenylalanine Metabolite hmdb:HMDB0000159
Citrulline Metabolite hmdb:HMDB0000904
Lysine Metabolite hmdb:HMDB0000182
Hippuric acid Metabolite hmdb:HMDB0000714
valine Metabolite hmdb:HMDB0000883
Insulin GeneProduct ensembl:ENSG00000254647

References

  1. Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity. Shaham O, Wei R, Wang TJ, Ricciardi C, Lewis GD, Vasan RS, et al. Mol Syst Biol. 2008;4:214. PubMed Europe PMC Scholia