Quercetin and Nf-kB / AP-1 induced cell apoptosis (WP3167)

Bos taurus

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Authors

Martina Summer-Kutmon , Linda Rieswijk , Eric Weitz , Lars Willighagen , and Egon Willighagen

Activity

last edited

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Cited In

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Organisms

Bos taurus

Communities

Annotations

Pathway Ontology

apoptotic cell death pathway

Participants

Label Type Compact URI Comment
Prostaglandin G2 Metabolite hmdb:HMDB0003235
Quercetin Metabolite hmdb:HMDB0005794
Prostaglandin H2 Metabolite hmdb:HMDB0001381
Arachidonic acid Metabolite hmdb:HMDB0001043
Prostaglandin I2 Metabolite hmdb:HMDB0001335
Thromboxane A2 Metabolite hmdb:HMDB0001452
Prostaglandin F2a Metabolite hmdb:HMDB0001139
Prostaglandin D2 Metabolite hmdb:HMDB0001403
Prostaglandin E2 Metabolite hmdb:HMDB0001220
COX1 GeneProduct ensembl:ENSBTAG00000043561 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4512
IKBKB GeneProduct ensembl:ENSBTAG00000007599 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000104365
NFKB1 GeneProduct ensembl:ENSBTAG00000020270 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000109320
MAFK GeneProduct ensembl:ENSBTAG00000019303 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7975
MAFG GeneProduct ensembl:ENSBTAG00000000040 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4097
ACOX2 GeneProduct ensembl:ENSBTAG00000004178 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000168306
FOS GeneProduct ensembl:ENSBTAG00000004322 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000170345
NOS1 GeneProduct ensembl:ENSBTAG00000002023 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000089250
VEGFA GeneProduct ensembl:ENSBTAG00000047561 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000112715
JUN GeneProduct ensembl:ENSBTAG00000004037 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000177606
MMP1 GeneProduct ensembl:ENSBTAG00000048029 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000196611
CYP2A6 GeneProduct ensembl:ENSBTAG00000047815 one of several possible phase 1 enzymes
HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000255974
NFE2L2 GeneProduct ensembl:ENSBTAG00000019255 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000116044
KEAP1 GeneProduct ensembl:ENSBTAG00000003543 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000079999
PGHS-2 GeneProduct ensembl:ENSBTAG00000014127 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5743
BIKBA Protein ensembl:ENSBTAG00000016683 HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P25963

References

  1. The role of phytochemicals in inhibition of cancer and inflammation: New directions and perspectives. Issa AY, Volate SR, Wargovich MJ. Journal of Food Composition and Analysis [Internet]. 2006 Aug;19(5):405–19. Available from: http://dx.doi.org/10.1016/j.jfca.2006.02.009 DOI Scholia
  2. Prostaglandins and leukotrienes: advances in eicosanoid biology. Funk CD. Science. 2001 Nov 30;294(5548):1871–5. PubMed Europe PMC Scholia
  3. Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin. Tanigawa S, Fujii M, Hou DX. Free Radic Biol Med. 2007 Jun 1;42(11):1690–703. PubMed Europe PMC Scholia
  4. Prostaglandins and inflammation. Ricciotti E, FitzGerald GA. Arterioscler Thromb Vasc Biol. 2011 May;31(5):986–1000. PubMed Europe PMC Scholia