Steroid biosynthesis (WP496)
Homo sapiens
Steroidogenesis is the biological process by which steroids are generated from cholesterol and transformed into other steroids. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP496 CPTAC Assay Portal].
Authors
Andrew Kwa , Martijn Van Iersel , Kristina Hanspers , Alex Pico , Anatolymikutin , Egon Willighagen , Martina Summer-Kutmon , Denise Slenter , Eric Weitz , and Finterly HuActivity
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Organisms
Homo sapiensCommunities
Annotations
Pathway Ontology
steroid hormone biosynthetic pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| Dehydroepiandrosterone | Metabolite | cas:53-43-0 | |
| Estradiol | Metabolite | cas:57-91-0 | |
| Progesterone | Metabolite | cas:57-83-0 | |
| Androstenediol | Metabolite | hmdb:HMDB0005849 | |
| Dihydrotestosterone | Metabolite | hmdb:HMDB0002961 | |
| Testosterone | Metabolite | cas:58-22-0 | |
| 17-alpha-OH-pregnenolone | Metabolite | hmdb:HMDB0000363 | |
| Estrone | Metabolite | cas:53-16-7 | |
| Pregnenolone | Metabolite | cas:145-13-1 | |
| 17-alpha-OH-progesterone | Metabolite | hmdb:HMDB0000374 | |
| Cholesterol | Metabolite | cas:57-88-5 | |
| Androstenedione | Metabolite | cas:63-05-8 | |
| HSD17B4 | GeneProduct | ncbigene:3295 | |
| HSD3B1 | GeneProduct | ncbigene:3283 | |
| Steroid 19-hydroxylase | GeneProduct | ensembl:ENSG00000120054 | |
| HSD17B2 | GeneProduct | ncbigene:3294 | |
| Hydroxyprogesterone aldolase | GeneProduct | eccode:4.1.2.30 | |
| F13B | GeneProduct | ncbigene:2165 | |
| HSD3B2 | GeneProduct | ncbigene:3284 | |
| CYP17A1 | GeneProduct | ncbigene:1586 | |
| HSD17B1 | GeneProduct | ncbigene:3292 | |
| HSD17B3 | GeneProduct | ncbigene:3293 | |
| HSD17B7 | GeneProduct | ncbigene:51478 |