Homologous recombination (WP186)

Homo sapiens

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Homologous recombination, also known as general recombination, is a type of genetic recombination in which nucleotide sequences are exchanged between two similar or identical strands of DNA. Source: [[wikipedia:Homologous_recombination|Wikipedia]] Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP186 CPTAC Assay Portal]

Authors

Thomas Kelder , Alex Pico , Martijn Van Iersel , Kristina Hanspers , Irene Hemel , Eric Weitz , Marvin Martens , and Egon Willighagen

Activity

last edited

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Organisms

Homo sapiens

Communities

Annotations

Pathway Ontology

homologous recombination pathway of double-strand break repair

Participants
Query Drugst.One

Label Type Compact URI Comment
POLD3 GeneProduct ensembl:ENSG00000077514
RAD51 GeneProduct ensembl:ENSG00000051180
RAD51 GeneProduct ensembl:ENSG00000051180
BRCA2 GeneProduct ensembl:ENSG00000139618
BRCA2 GeneProduct ensembl:ENSG00000139618
BRCA2 GeneProduct ensembl:ENSG00000139618
RPA1 ? GeneProduct ensembl:ENSG00000132383
RPA1 ? GeneProduct ensembl:ENSG00000132383
RPA1 ? GeneProduct ensembl:ENSG00000132383
NBN GeneProduct ensembl:ENSG00000104320
RAD52 GeneProduct ensembl:ENSG00000002016
RAD52 GeneProduct ensembl:ENSG00000002016
POLD4 GeneProduct ensembl:ENSG00000175482
RAD51 GeneProduct ensembl:ENSG00000051180
ATM GeneProduct ensembl:ENSG00000149311
RAD54B GeneProduct ensembl:ENSG00000197275
MRE11A GeneProduct ensembl:ENSG00000020922
RAD51 GeneProduct ensembl:ENSG00000051180
BRCA2 GeneProduct ensembl:ENSG00000139618
POLD1 GeneProduct ensembl:ENSG00000062822
RPA1 ? GeneProduct ensembl:ENSG00000132383 Type you comment here
POLD2 GeneProduct ensembl:ENSG00000106628
RAD52 GeneProduct ensembl:ENSG00000002016
RAD50 GeneProduct ensembl:ENSG00000113522
ATM GeneProduct ensembl:ENSG00000149311
RAD54B GeneProduct ensembl:ENSG00000197275

References

  1. Molecular biology of the cell [Internet]. 2003. 660 p. Available from: https://books.google.com/books/about/Molecular_biology_of_the_cell.html?hl=&id=n-pFAQAAIAAJ OpenLibrary Worldcat