Striated muscle contraction pathway (WP383)
Homo sapiens
Muscle contraction is the process where muscle tissue is activated by a signal from the nervous system. In the case of voluntary action, the nervous signals are initiated from the brain by so-called action potentials. With reflexes, these potentials are coming directly from the spinal cord. Striated muscles are a group of muscles also called skeletal and cardiac muscle tissue. Proteins on this pathway have targeted assays available via the CPTAC Assay Portal.
Authors
Nathan Salomonis , Martijn Van Iersel , Joanna Fong , Kristina Hanspers , Andra Waagmeester , Marianthi Kalafati , Marvin Martens , Friederike Ehrhart , Eric Weitz , Martina Summer-Kutmon , and Egon WillighagenActivity
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Cited In
- PolySTest: Robust Statistical Testing of Proteomics Data with Missing Values Improves Detection of Biologically Relevant Features (2020).
- SARS-CoV-2 infection of human iPSC-derived cardiac cells predicts novel cytopathic features in hearts of COVID-19 patients (2020).
- Hematopoietic stem-cell senescence and myocardial repair - Coronary artery disease genotype/phenotype analysis of post-MI myocardial regeneration response induced by CABG/CD133+ bone marrow hematopoietic stem cell treatment in RCT PERFECT Phase 3 (2020).
- Parallel use of human stem cell lung and heart models provide insights for SARS-CoV-2 treatment (2023).
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Organisms
Homo sapiensCommunities
Annotations
Cell Type Ontology
striated muscle cellPathway Ontology
regulatory pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| TNNI3 | GeneProduct | ncbigene:7137 | |
| DES | GeneProduct | ncbigene:1674 | |
| MYBPC1 | GeneProduct | ncbigene:4604 | |
| TCAP | GeneProduct | ncbigene:8557 | |
| TNNI1 | GeneProduct | ncbigene:7135 |