Fatty acid biosynthesis (WP336)
Mus musculus
The production of fatty acids from acetyl-CoA and NADPH through the use of enzymes known as fatty acid synthases is referred to as fatty acid synthesis. This biological process occurs within the cytoplasm of cells. The majority of acetyl-CoA that is transformed into fatty acids originates from carbohydrates through the glycolytic pathway.
Authors
Kdahlquist , Chris Evelo , JT. Saito , Christine Chichester , Martina Summer-Kutmon , Eric Weitz , Egon Willighagen , and Alex PicoActivity
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Cited In
- Bioenergetic defects in muscle fibers of RYR1 mutant knock-in mice associated with malignant hyperthermia (2020).
- Quizalofop-p-Ethyl Induces Adipogenesis in 3T3-L1 Adipocytes (2019).
- Advanced Running Performance by Genetic Predisposition in Male Dummerstorf Marathon Mice (DUhTP) Reveals Higher Sterol Regulatory Element-Binding Protein (SREBP) Related mRNA Expression in the Liver and Higher Serum Levels of Progesterone (2016).
- Proteomic profiling of salivary gland after nonviral gene transfer mediated by conventional plasmids and minicircles (2014).
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Organisms
Mus musculusCommunities
Annotations
Pathway Ontology
fatty acid biosynthetic pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| Malonyl-CoA | Metabolite | hmdb:HMDB0001175 | |
| Acetyl-CoA | Metabolite | hmdb:HMDB0001206 | |
| Fasn | GeneProduct | ncbigene:14104 | |
| Echs1 | GeneProduct | ncbigene:93747 | |
| Acsl5 | GeneProduct | ncbigene:433256 | |
| Pecr | GeneProduct | ncbigene:111175 | |
| Echdc2 | GeneProduct | ncbigene:52430 | |
| Acaca | GeneProduct | ncbigene:107476 | |
| Echdc1 | GeneProduct | ncbigene:52665 | |
| Acsl4 | GeneProduct | ncbigene:50790 | |
| Scd1 | GeneProduct | ncbigene:20249 | |
| Acss2 | GeneProduct | ncbigene:60525 | |
| Echdc3 | GeneProduct | ncbigene:67856 | |
| Acly | GeneProduct | ncbigene:104112 | |
| Acsl3 | GeneProduct | ncbigene:74205 | |
| Hadh | GeneProduct | ncbigene:15107 | |
| Acacb | GeneProduct | ncbigene:100705 | |
| Acsl1 | GeneProduct | ncbigene:14081 | |
| Pcx | GeneProduct | ncbigene:18563 | |
| Acaa2 | GeneProduct | ncbigene:52538 | |
| Mecr | GeneProduct | ncbigene:26922 | |
| Decr1 | GeneProduct | ncbigene:67460 | |
| Acsl6 | GeneProduct | ncbigene:216739 | |
| Ech1 | GeneProduct | ncbigene:51798 |