Blood clotting cascade (WP3251)

Bos taurus

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Coagulation is a complex process by which blood forms clots. It is an important part of hemostasis (the cessation of blood loss from a damaged vessel), wherein a damaged blood vessel wall is covered by a platelet and fibrin-containing clot to stop bleeding and begin repair of the damaged vessel. Disorders of coagulation can lead to an increased risk of bleeding (hemorrhage) or clotting (thrombosis). Source: [[wikipedia:Coagulation|Wikipedia]]

Authors

Martina Summer-Kutmon , Eric Weitz , and Egon Willighagen

Activity

last edited

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Cited In

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Organisms

Bos taurus

Communities

Annotations

Pathway Ontology

coagulation cascade pathway

Participants

Label Type Compact URI Comment
Fibrin Metabolite cas:9001-31-4
Zinc Metabolite hmdb:HMDB0015532
F10 GeneProduct ensembl:ENSBTAG00000016385 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2159
F2 GeneProduct ensembl:ENSBTAG00000007148 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2147
F12 GeneProduct ensembl:ENSBTAG00000018872 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2161
KLKB1 GeneProduct ensembl:ENSBTAG00000009501 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3818
FGG GeneProduct ensembl:ENSBTAG00000006745 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2266
PLG GeneProduct ensembl:ENSBTAG00000001271 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5340
F9 GeneProduct ensembl:ENSBTAG00000004003 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2158
PLAU GeneProduct ensembl:ENSBTAG00000005947 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5328
FGB GeneProduct ensembl:ENSBTAG00000022120 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2244
KLK1 GeneProduct ensembl:ENSBTAG00000018539 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3816
VWF GeneProduct ensembl:ENSBTAG00000012265 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7450
F13B GeneProduct ensembl:ENSBTAG00000000070 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2165
F11 GeneProduct ensembl:ENSBTAG00000003572 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2160
SERPINF2 GeneProduct ensembl:ENSBTAG00000020859 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5345
PLAT GeneProduct ensembl:ENSBTAG00000001244 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5327
SERPINB2 GeneProduct ensembl:ENSBTAG00000023198 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5055
SERPINE1 GeneProduct ensembl:ENSBTAG00000014465 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5054
F8 GeneProduct ensembl:ENSBTAG00000010726 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2157
F7 GeneProduct ensembl:ENSBTAG00000007411 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2155

References

  1. The current status of coagulation. Luchtman-Jones L, Broze GJ Jr. Ann Med. 1995 Feb;27(1):47–52. PubMed Europe PMC Scholia