Khanspers

Glycosaminoglycan degradation

Amino acid metabolism

Electron transport chain: OXPHOS system in mitochondria

Proteoglycan biosynthesis

Cytoplasmic ribosomal proteins

Metabolic reprogramming in colon cancer

SCFA and skeletal muscle substrate metabolism

Pyrimidine metabolism

Fatty acid beta-oxidation

Somatic sex determination

Photodynamic therapy-induced AP-1 survival signaling

Superpathway polyamine biosynthesis

Ubiquinol-6 biosynthesis from 4-hydroxybenzoate

Superpathway of serine and glycine biosynthesis

Serotonin HTR1 group and FOS pathway

Inhibition of GNAQ-regulated signaling in uveal melanoma

Serotonin and anxiety

Glycine biosynthesis

Mitochondrial fatty acid oxidation disorders

Leucine degradation

Leucine biosynthesis

NAD salvage pathway V

De novo NAD biosynthesis

Ergosterol biosynthesis

Glutamate degradation IX

Tryptophan degradation via kynurenine

Glutathione-glutaredoxin redox reaction

Sphingolipid biosynthesis

Glucose-1-phosphate metabolism

Glutathione biosynthesis

Gluconeogenesis

Asparagine biosynthesis

Arginine degradation

Chorismate biosynthesis

Asparagine degradation

Arginine biosynthesis

Cysteine biosynthesis from homoserine

Cholesterol biosynthesis

Colanic acid building blocks biosynthesis

Pentose phosphate pathway

Oxidative stress in pulmonary tissue

Phospholipid biosynthesis

Salvage pathways of pyrimidine deoxyribonucleotides

Complement and coagulation cascades

Pentose pathway, non-oxidative branch

Na/K-ATPase/Src signaling

Mammary gland development: involution - stage 4 of 4

Mammary gland development: puberty - stage 2 of 4

Mammary gland development: embryonic development - stage 1 of 4

Oncostatin M signaling

B cell receptor signaling

Sterol regulatory element-binding proteins (SREBP) signaling

Hepatocyte growth factor receptor signaling

Dopaminergic neurogenesis

Effect of dasatinib on the BCR-ABL signaling pathway

Targeted agents in triple negative breast cancer

Molecular pathway for oxidative stress

Integrated breast cancer pathway

Somatroph axis (GH) and its relationship to dietary restriction and aging

De novo biosynthesis of pyrimidine ribonucleotides

Regulation of cytotoxic T cell responses by Malat1 - miR-15/16 circuit

Hallmark of cancer: non-mutational epigenetic reprogramming

Hallmark of cancer: sustaining proliferative signaling

Omega-3-fatty acids in senescence

Mammary gland development: pregnancy and lactation - stage 3 of 4

Fanconi anemia

De novo biosynthesis of purine nucleotides

Type 2 papillary renal cell carcinoma

NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence

Development and heterogeneity of the ILC family

miR-targeted genes in squamous cell

miR-targeted genes in muscle cell

miR-targeted genes in lymphocytes

miR-targeted genes in leukocytes

miR-targeted genes in adipocytes

Small cell lung cancer

Sulfate assimilation pathway

TCA cycle - detailed

Tyrosine biosynthesis

Pantothenate and coenzyme A biosynthesis

Homocysteine and cysteine interconversion

MAPK signaling pathway

Phosphatidic acid and phospholipid biosynthesis

Steroidogenic pathway

Threonine and methionine biosynthesis

De novo biosynthesis of pyrimidine deoxyribonucleotides

Threonine biosynthesis

Glycolysis

Aspartate biosynthesis

Glutamate biosynthesis superpathway

Superpathway of branched chain amino acid biosynthesis

Histidine, purine, and pyrimidine superpathway

Isoleucine biosynthesis

SREBF and miR33 in cholesterol and lipid homeostasis

Valine biosynthesis

Glutamate degradation I

Triglyceride biosynthesis

Isoleucine degradation

Vitamin K metabolism and activation of dependent proteins

Statin inhibition of cholesterol production

Lipid metabolism pathway

Gastrin signaling

Pyrimidine ribonucleotide salvage pathways

Fatty acid oxidation

Histidine biosynthesis

Liver steatosis adverse outcome pathway

Pyruvate dehydrogenase pathway

Glycolysis and Gluconeogenesis

Mitochondrial unfolded-protein response

Copper homeostasis

Programmed cell death

Heterochronic gene regulation of development

Cell engulfment

EGF signaling in vulval development

Notch signaling in vulval development

Mechanosensory inputs influence pharyngeal activity via ivermectin sensitivity genes

daf-2 or insulin signaling pathway

Hedgehog-related genes

TOR signaling

Vulval development

Cell division: first embryonic mitosis

Biogenic amine synthesis

Vulval development and SynMuv

RNA interference and miRNA

Wnt signaling

Metapathway signal transduction

LIN-12/Notch Lateral Signaling

Glucocorticoid effect on target gene expression

Pentose phosphate metabolism

Acute myeloid leukemia

Hedgehog signaling

Phase I biotransformations, non-P450

Principal pathways of carbon metabolism

Cancer pathways

AMP-activated protein kinase signaling

Follicle stimulating hormone (FSH) signaling

IL5 signaling

Clock-controlled autophagy in bone metabolism

DNA IR-double strand breaks and cellular response via ATM

Lysine biosynthesis

Orexin receptor pathway

Burn wound healing

Trans-sulfuration, one-carbon metabolism and related pathways

T-cell receptor signaling

Estradiol regulation in porto-sinusoidal vascular disease

mBDNF and proBDNF regulation of GABA neurotransmission

Insulin signaling

Melanoma

Synaptic signaling associated with autism spectrum disorder

Ras signaling

Chromosomal and microsatellite instability in colorectal cancer

Clear cell renal cell carcinoma pathways

Hepatitis C and hepatocellular carcinoma

Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling

Hepatocyte growth factor receptor signaling

Focal adhesion

Glucocorticoid receptor pathway

Spinal cord injury

Leptin signaling

IL1 signaling

Androgen receptor signaling

Endoplasmic reticulum stress response in coronavirus infection

Osteoblast differentiation and related diseases

HDAC6 interactions in the central nervous system

Pathogenesis of SARS-CoV-2 mediated by nsp9-nsp10 complex

Vitamin D in inflammatory diseases

PI3K/AKT/mTOR - vitamin D3 signaling

Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling

Pathogenic Escherichia coli infection

Nuclear receptors

Vitamin B12 metabolism

Tamoxifen metabolism

T cell receptor and co-stimulatory signaling

Selenium metabolism / selenoproteins

Toll-like receptor signaling

TYROBP causal network in microglia

Focal adhesion: PI3K-Akt-mTOR-signaling

Ovarian infertility

CAMKK2 pathway

LTF danger signal response pathway

Pathways affected in adenoid cystic carcinoma

Serotonin receptor 2 and ELK-SRF/GATA4 signaling

Sudden infant death syndrome (SIDS) susceptibility pathways

Canonical and non-canonical TGF-B signaling

NAD+ biosynthetic pathways

HIF1A and PPARG in cardiac hypertropthy

Calcium regulation in cardiac cells

NAD biosynthesis II from tryptophan

G1 to S cell cycle control

MicroRNA network associated with chronic lymphocytic leukemia

NRF2-ARE regulation

Ciliary landscape

Vitamins A and D - action mechanisms

ncRNAs involved in STAT3 signaling in hepatocellular carcinoma

ncRNAs in Wnt signaling in hepatocellular carcinoma

Thermogenesis

Mitochondrial fission and fusion

Malate-aspartate shuttle

Ferroptosis

Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells

Pancreatic adenocarcinoma pathway

PI3K-Akt signaling

Imatinib and chronic myeloid leukemia

IL6 signaling

Thymic stromal lymphopoietin (TSLP) signaling

TP53 network

FGFR4 p.G388R signaling

N-glycan biosynthesis

Sialylation

16p11.2 proximal deletion syndrome

Major receptors targeted by epinephrine and norepinephrine

Metabolism of alpha-linolenic acid

Cancer immunotherapy by PD-1 blockade

Blood clotting and drug effects

Translation inhibitors in chronically activated PDGFRA cells

MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement

Interactions between immune cells and microRNAs in tumor microenvironment

Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms

Control of immune tolerance by vasoactive intestinal peptide

Relationship between inflammation, COX-2 and EGFR

Platelet-mediated interactions with vascular and circulating cells

Estrogen receptor pathway

Pathophysiological roles of DUX4 in FSHD1

Th17 cell differentiation pathway

FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma

Inflammatory response pathway

Prader-Willi and Angelman syndrome

ADHD and autism (ASD) pathways

5q35 copy number variation

17p13.3 (YWHAE) copy number variation

4p16.3 copy number variation

Affected pathways in Duchenne muscular dystrophy

ALA oxylipin metabolism

SARS-CoV-2 B.1.1.7 variant antagonises innate immune activation

Vasopressin-regulated water reabsorption

Modulators of TCR signaling and T cell activation

Galanin receptor pathway

p53 transcriptional gene network

Complement system

Mitochondrial long chain fatty acid beta-oxidation

Amino acid conjugation

Aflatoxin B1 metabolism

Glucuronidation

Estrogen metabolism

Arylamine metabolism

Arachidonate epoxygenase / epoxide hydrolase

Oxidative phosphorylation

Type II interferon signaling

Interferon type I signaling

Exercise-induced circadian regulation

Smith-Magenis and Potocki-Lupski syndrome copy number variation

NF1 copy number variation syndrome

Kynurenine pathway and links to cell senescence

Pentose phosphate pathway in senescent cells

Airway smooth muscle cell contraction

TCA cycle

Aerobic glycolysis

Mitochondrial gene expression

ESC pluripotency pathways

Ebstein-Barr virus LMP1 signaling

Post-COVID neuroinflammation

Aspirin and miRNAs

Aerobic glycolysis - augmented

Fragile X syndrome

Acute viral myocarditis

Flavan-3-ol metabolic pathway

Purine metabolism and related disorders

Ebola virus infection in host

Embryonic stem cell pluripotency pathways

Angiopoietin-like protein 8 regulatory pathway

Dengue-2 interactions with complement and coagulation cascades

Nanomaterial-induced inflammasome activation

Zinc homeostasis

Pluripotent stem cell differentiation pathway

Folate metabolism

Hair follicle development: cytodifferentiation - stage 3 of 3

DNA damage response (only ATM dependent)

TROP2 regulatory signaling

ROS in COVID-19 endothelial dysfunction

Immune response to tuberculosis

ApoE and miR-146 in inflammation and atherosclerosis

ApoE and miR-146 in inflammation and atherosclerosis

Seed development

Androgen receptor network in prostate cancer

Oxylipins pathways

Endothelin pathways

RANKL/RANK signaling

Nucleotide-binding oligomerization domain (NOD) pathway

Folic acid network

Folic acid network

Mitochondrial gene expression

Complement and coagulation cascades

Monoamine transport

Vitamin A and carotenoid metabolism

MAPK cascade

RAC1/PAK1/p38/MMP2 pathway

Statin pathway

Sulfur amino acid biosynthesis

Folate metabolism

Histidine metabolism

Microtubule cytoskeleton regulation

Phosphodiesterases in neuronal function

Polycystic kidney disease pathway

Axon guidance

miRNA regulation of prostate cancer signaling

Chemokine signaling

Folic acid biosynthesis

Hippo signaling regulation

Extracellular vesicle-mediated signaling in recipient cells

Common pathways underlying drug addiction

Pilocytic astrocytoma

Estrogen signaling

ErbB signaling

Notch signaling

FLT3 p.Gln640SerfsTer8 signaling

IL19 signaling

IL26 signaling

ID signaling

G13 signaling

Urotensin-II-mediated signaling

IL2 signaling

PKC-gamma calcium signaling in ataxia

IL18 signaling

Hedgehog signaling

Interferon-mediated signaling

EGF/EGFR signaling

Fibrin complement receptor 3 signaling

p38 MAPK signaling

Wnt signaling and pluripotency

IL4 signaling

ROBO4 and VEGF signaling crosstalk

PPAR signaling

MAPK and NFkB signaling inhibited by Yersinia YopJ

MAPK signaling

Wnt/beta-catenin signaling in leukemia

Equilibrium signaling of differentiated cells

Wnt signaling

G protein signaling

Kit receptor signaling

Nod-like receptor (NLR) signaling

IL3 signaling

ATM signaling

Alpha 6 beta 4 signaling

Brain-derived neurotrophic factor (BDNF) signaling

Corticotropin-releasing hormone signaling

IL11 signaling

TNF-alpha signaling

Glioblastoma signaling

IL9 signaling

IL17 signaling

IL7 signaling

Prolactin signaling

TNF-related weak inducer of apoptosis (TWEAK) signaling

Thyroid stimulating hormone (TSH) signaling

Triacylglyceride synthesis

Hepatitis B infection

H19, Rb-E2F1, and CDK-beta-catenin in colorectal cancer

PI3K-AKT-mTOR signaling and therapeutic opportunities in prostate cancer

Bile acid synthesis and enterohepatic circulation

Heart development

Selenium metabolism and selenoproteins

Prion disease pathway

Metabolic epileptic disorders

Intracellular trafficking proteins involved in CMT neuropathy

Sulfur degradation

Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins

DNA replication

Monoamine GPCRs

Monoamine GPCRs

Type I collagen synthesis in the context of osteogenesis imperfecta

Head and neck squamous cell carcinoma

Circulating monocytes and cardiac macrophages in diastolic dysfunction

Oligodendrocyte specification and differentiation, leading to myelin components for CNS

Extracellular vesicles in the crosstalk of cardiac cells

MET in type 1 papillary renal cell carcinoma

Development of pulmonary dendritic cells and macrophage subsets

Initiation of transcription and translation elongation at the HIV-1 LTR

Genes targeted by miRNAs in adipocytes

Mismatch repair

Rubinstein-Taybi syndrome 1

STING pathway in Kawasaki-like disease and COVID-19

Lipids measured in liver metastasis from breast cancer

Degradation pathway of sphingolipids, including diseases

Wnt signaling in kidney disease

Wnt signaling in kidney disease

MicroRNA for targeting cancer growth and vascularization in glioblastoma

Mecp2 and associated Rett syndrome

Hypothetical craniofacial development pathway

Ectodysplasin A signaling in hair follicle development

Wnt myofibroblastic activation of hepatic stellate cells

Cytokines and inflammatory response

Heme biosynthesis

Measles virus infection

Altered glycosylation of MUC1 in tumor microenvironment

Intracellular auxin transport

Hematopoietic stem cell differentiation

Glial cell differentiation

RAS and bradykinin pathways in COVID-19

Serotonin and anxiety-related events

ERK pathway in Huntington's disease

Physiological and pathological hypertrophy of the heart

TCA cycle (aka Krebs or citric acid cycle)

Oxidative stress response

ATM signaling in development and disease

Steroid biosynthesis

Hypothesized pathways in pathogenesis of cardiovascular disease

Glutathione metabolism

Ciliopathies

TGF-beta receptor signaling in skeletal dysplasias

FGF23 signaling in hypophosphatemic rickets and related disorders

Multiple epiphyseal dysplasia and pseudoachondroplasia genes

Autosomal recessive osteopetrosis pathways

Somitogenesis in the context of spondylocostal dysostosis

Endochondral ossification

DNA damage response

p53 pathway

Hypoxia-dependent differentiation of myoblasts

Hypoxia-dependent self-renewal of myoblasts

FABP4 in ovarian cancer

Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors

miRNA role in immune response in sepsis

Epithelial to mesenchymal transition in colorectal cancer

miRNA regulation of p53 pathway in prostate cancer

Dysregulated miRNA targeting in insulin/PI3K-AKT signaling

Cell-type dependent selectivity of CCK2R signaling

Photodynamic therapy-induced NF-kB survival signaling

Hypoxia-mediated EMT and stemness

Focal adhesion: PI3K-Akt-mTOR signaling pathway

DNA replication

One-carbon metabolism

GABA receptor signaling

Breast cancer pathway

TCA cycle nutrient use and invasiveness of ovarian cancer

Irinotecan pathway

Angiotensin II receptor type 1 pathway

4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression

ATR signaling

Regulation of apoptosis by parathyroid hormone-related protein

Striated muscle contraction pathway

Amplification and expansion of oncogenic pathways as metastatic traits

Vitamin D metabolism

Endometrial cancer

ACE inhibitor pathway

Angiogenesis

Cholesterol biosynthesis with skeletal dysplasias

Disorders of folate metabolism and transport

NAD metabolism, sirtuins and aging

Bladder cancer

Vitamin B6-dependent and responsive disorders

Neurotransmitter disorders

Growth factors and hormones in beta cell proliferation

Alzheimer's disease

Burn wound healing

Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway

Gene regulatory network modeling somitogenesis

Histone modifications

Type II diabetes mellitus

OSX and miRNAs in tooth development

miRNA targets in ECM and membrane receptors

Parkinson's disease pathway

Copper metabolism

FGFR3 signaling in chondrocyte proliferation and terminal differentiation

Hippo-Merlin signaling dysregulation

Methionine metabolism leading to sulfur amino acids and related disorders

MTHFR deficiency

Vitamin B12 disorders

MECP2 and associated Rett syndrome

Complement activation

Copper homeostasis

Apoptosis

Codeine and morphine metabolism

Phase I biotransformations, non-P450

Phase I biotransformations, non-P450

Phase I biotransformations, non-P450

Cancer immunotherapy by CTLA4 blockade

BDNF-TrkB signaling

Amyotrophic lateral sclerosis (ALS)

Cholesterol biosynthesis pathway

Apoptosis modulation and signaling

Fructose and mannose metabolism

Glycolysis and gluconeogenesis

Acetylcholine synthesis

Synaptic vesicle pathway

Alzheimer's disease and miRNA effects

Focal adhesion

Nucleotide GPCRs

Tryptophan metabolism

Insulin signaling

Monoamine GPCRs

Steroid biosynthesis

Regulation of actin cytoskeleton

GPCRs, other

Inflammatory response pathway

Notch signaling pathway

Peptide GPCRs

RIOK1 and RIOK2 in EGFR- and PI3K-mediated tumorigenesis

T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection

MYD88 distinct input-output pathway

Canonical and non-canonical Notch signaling

EV release from cardiac cells and their functional effects

High-osmolarity glycerol (HOG) pathway

Metapathway biotransformation Phase I and II

Interleukin-1 (IL-1) structural pathway

Non-small cell lung cancer

Methionine de novo and salvage pathway

Non-canonical Wnt pathway

Hematopoietic stem cell gene regulation by GABP alpha/beta complex

Blood clotting cascade

Cardiac progenitor differentiation

Glycolysis in senescence

Carnosine metabolism of glial cells

Nucleotide excision repair

Base excision repair

Non-homologous end joining

Wnt signaling pathway and pluripotency

Kennedy pathway from sphingolipids

lncRNA in canonical Wnt signaling and colorectal cancer

Pleural mesothelioma

Wnt signaling

Regulation of sister chromatid separation at the metaphase-anaphase transition

Cell cycle

Transcriptional activation by NRF2 in response to phytochemicals

EGFR tyrosine kinase inhibitor resistance

PDGFR-beta pathway

MFAP5-mediated ovarian cancer cell motility and invasiveness

Hippo-YAP signaling

TCA cycle (plant)

Gibberellin A12 biosynthesis

Alanine and aspartate metabolism

Diet-dependent trimethylamine/trimethylamine N-oxide metabolism

Osteoblast signaling

Genetic alterations of lung cancer

Nicotine effect on chromaffin cells

Osteoclast signaling

Pre-implantation embryo

Glycerophospholipid biosynthetic pathway

Comprehensive IL-17A signaling

Aryl hydrocarbon receptor pathway

Integrated cancer pathway

VEGF-receptor signal transduction

VEGFR-3 signaling

Cori cycle

Peroxisomal beta-oxidation of tetracosanoyl-CoA

Kennedy pathway

Iron homeostasis

Folate-alcohol and cancer pathway hypotheses

Transcription factors regulate miRNAs related to cardiac hypertrophy

MicroRNAs in cardiomyocyte hypertrophy

Energy metabolism

Flavonoid biosynthesis

miRNA regulation of DNA damage response

Regulation of cardiac hypertrophy by miR-208

Oxidative damage response

Glycine metabolism

Opioid receptor pathways

White fat cell differentiation

Dopaminergic neurogenesis

AGE/RAGE pathway

Heart development

Nicotine effect on dopaminergic neurons

Fluoropyrimidine activity

Mitochondrial long chain fatty acid beta-oxidation

Target of rapamycin signaling

Photosynthetic carbon reduction

Serotonin transporter activity

VEGFA-VEGFR2 signaling

Apoptosis modulation by HSP70

Osteoblast signaling

Notch signaling

Small ligand GPCRs

Adipogenesis genes

mRNA processing

Eukaryotic transcription initiation

Fas ligand pathway and stress induction of heat shock proteins

Nuclear receptors in lipid metabolism and toxicity

Myometrial relaxation and contraction pathways

S1P receptor signal transduction

CFTR activity in the plasma membrane

TNF-alpha and mucus production in lung epythelium

Intracellular trafficking of CFTR

Interactions between CFTR and other ion channels

Osteopontin signaling

Homologous recombination

Integrin-mediated cell adhesion

Bone morphogenic protein signaling and regulation

Translation factors

TGF-beta receptor signaling

Biogenic amine synthesis

Hypertrophy model

Sulfation biotransformation reaction

Glucose homeostasis

Abscisic acid biosynthesis

Flower development

Glycogen synthesis and degradation

Prostaglandin synthesis and regulation

Fructose metabolism in proximal tubules

Iron-sulfur cluster biogenesis

Serotonin receptor 4/6/7 and NR3C signaling

IL-9 signaling pathway

Amino acid conjugation of benzoic acid

IL-6 signaling pathway

Metapathway biotransformation

Fatty acid biosynthesis

Mevalonate pathway

Wnt signaling pathway and pluripotency

ATM signaling pathway

Glycerol teichoic acid biosynthesis

Catecholamine synthesis

Oxidative stress and redox pathway

Metabolism of tetrahydrocannabinol (THC)

Cardiac progenitor differentiation

Pentose phosphate pathway

Carbon assimilation C4 pathway

Oxidation by cytochrome P450

Oxidation by cytochrome P450

mRNA processing

Ethanol effects on histone modifications

Heme biosynthesis

Sphingolipid metabolism: integrated pathway

Cholesterol metabolism with Bloch and Kandutsch-Russell pathways

Pregnane X receptor pathway

Heme biosynthesis

Eicosanoid synthesis

Selenium micronutrient network

Retinol metabolism

Retinol metabolism

mRNA processing

Myometrial relaxation and contraction pathways

mRNA processing

mRNA processing

Myometrial relaxation and contraction pathways

mRNA processing

mRNA Processing

Homologous recombination

Resistin as a regulator of inflammation

TLR4 signaling and tolerance

PDGF pathway

Glycolysis and gluconeogenesis

Nucleotide GPCRs

FAS pathway and stress induction of HSP regulation

Selenium micronutrient network

Acetogenesis

miRNA degrading enzymes

IL1 and megakaryocytes in obesity

Allograft rejection

Microglia pathogen phagocytosis pathway

Regulation of actin cytoskeleton

HIPK2 in kidney fibrosis

ABA biosynthesis

DNA IR-damage and cellular response via ATR

TGF-beta signaling pathway

miR-222 in exercise-induced cardiac growth

Melatonin metabolism and effects

Aryl hydrocarbon receptor pathway

SARS-CoV-2 and ACE2 receptor: molecular mechanisms

BDNF pathway

MAPK signaling pathway

Salmonella virulence regulatory network

Fibrin complement receptor 3 signaling pathway

Serine metabolism

Long-day flowering time pathway

Cell differentiation - index

Beta-oxidation of unsaturated fatty acids

Effect of L-carnitine on metabolism

Parkin-ubiquitin proteasomal system pathway

Vitamin D receptor pathway

Nanoparticle triggered regulated necrosis

Homologous recombination

Nicotine metabolism in liver cells

Gut-liver indole metabolism

Tryptophan metabolism

Role of carnosine in muscle contraction

Hereditary leiomyomatosis and renal cell carcinoma pathway

Host-pathogen interaction of human coronaviruses - MAPK signaling

Oxidation by cytochrome P450

Primary focal segmental glomerulosclerosis (FSGS)

Arrhythmogenic right ventricular cardiomyopathy

Ketogenesis and ketolysis

Urea cycle and metabolism of amino groups

DDX1 as a regulatory component of the Drosha microprocessor

Hypoxia-dependent proliferation of myoblasts

NAD+ metabolism

Beta-oxidation meta-pathway

miR-222 in exercise-induced cardiac growth

Fatty acid beta-oxidation meta-pathway

Soluble ACE2-mediated cell entry of SARS-CoV-2

Polar auxin transport

Wnt signaling pathway

Glucosinolate biosynthesis from branched-chain amino acid

Glucosinolate biosynthesis from methionine

Ketone bodies synthesis and degradation

Nodal signaling pathway

BMP signaling pathway

Eukaryotic transcription initiation

Homologous recombination

Mismatch repair

ERK1-ERK2 MAPK cascade

Leptin-insulin signaling overlap

Lung fibrosis

Flavonoid pathway

Mesodermal commitment pathway

Eukaryotic transcription initiation

miRNAs involved in DNA damage response

FGF signaling pathway

Sphingolipid pathway

Monoamine GPCRs

Cholesterol biosynthesis

Homologous recombination

Regulation of Wnt / B-catenin signaling by small molecule compounds

Crystal toxin triggered necrosis pathway

FAS pathway and stress induction of HSP regulation

Signal transduction of S1P receptor

Eukaryotic transcription initiation

Calcium regulation in cardiac cells

Exercise-induced circadian regulation

Mapk signaling pathway

Alpha 6 beta 4 integrin signaling pathway

Inflammatory response pathway

GPCRs, class B secretin-like

Osteoclast signaling

IL-2 signaling pathway

Matrix metalloproteinases

PDGFR-alpha and STMN1 cooperate to exacerbate cytotoxic effects of vinblastine

Mitochondrial long chain fatty acid beta-oxidation

IL-6 signaling pathway

Robo4 and VEGF signaling pathways crosstalk

BMP signaling pathway in eyelid development

Interleukin-1 induced activation of NF-kB

GPCRs, small ligand

GPCRs, class C metabotropic glutamate, pheromone

Eicosanoid synthesis

IL-17 signaling pathway

Translation factors

Electron transport chain

Neural crest differentiation

Complement activation, classical pathway

GPCRs, class A rhodopsin-like

Apoptosis modulation by HSP70

IL-5 signaling pathway

GPCRs, odorant

GPCRs, non-odorant

Methylation pathways

Catalytic cycle of mammalian flavin-containing monooxygenases (FMOs)

DNA mismatch repair

GPCRs, class C metabotropic glutamate, pheromone

DNA repair pathways, full network

Direct reversal repair

GPCRs, class A rhodopsin-like

NO/cGMP/PKG mediated neuroprotection

BMP signaling in eyelid development

TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition

Toll-like receptor signaling related to MyD88

Physico-chemical features and toxicity-associated pathways

lncRNA-mediated mechanisms of therapeutic resistance

Interactions between LOXL4 and oxidative stress pathway

Metabolism of dichloroethylene by CYP450

Circadian rhythm genes

GPCRs, class B secretin-like

Constitutive androstane receptor pathway

Hair follicle development: organogenesis - part 2 of 3

Felbamate metabolism

Cardiac hypertrophic response

TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc)

Gastric cancer network 2

Gastric cancer network 1

Fatty acid omega-oxidation

Cell differentiation - expanded index

SRF and miRs in smooth muscle differentiation and proliferation

Matrix metalloproteinases

GPCRs, other

Nuclear receptors in lipid metabolism and toxicity

Small ligand GPCRs

Ketone bodies synthesis and degradation

Exercise-induced circadian regulation

TSLP signaling pathway

Isoprenoid precursor biosynthesis in Pf apicoplasts

IGF-1 signaling

Growth hormone receptor (GHR) signaling

Osteoblast signaling

Ganglio sphingolipid metabolism

Ketone bodies synthesis and degradation

Inflammatory response pathway

Acetylcholine synthesis

ACE inhibitor pathway

Ketone bodies synthesis and degradation

Glycolysis and gluconeogenesis

MAPK signaling pathway

Cell cycle and cell division

Allantoin degradation

Phenylalanine, tyrosine, and tryptophan biosynthesis

Phenylalanine biosynthesis

Tryptophan biosynthesis

DNA replication

Regulation of actin cytoskeleton

mRNA processing

Mitochondrial long chain fatty acid beta-oxidation

Glucose sensing and signaling

Toll, IMD, JAK/STAT pathways for immune response to pathogens

Genetic interactions between sugar and hormone signaling

Calcium regulation in cardiac cells

FAS pathway and stress induction of HSP regulation

Ketone bodies synthesis and degradation

Polyol pathway

GPR40 pathway

miRNA biogenesis

Neural crest differentiation

EPO receptor signaling

Exercise-induced circadian regulation

Wnt signaling pathway

Apoptosis modulation by HSP70

FAS pathway and stress induction of HSP regulation

Cardiovascular signaling

ACE inhibitor pathway

Complement and coagulation cascades

Translation factors

mRNA processing

Notch signaling pathway

Biosynthesis of aldosterone and cortisol

Hedgehog signaling pathway

Osteoclast

Apoptosis modulation by HSP70

Oxidative damage response

Thick ascending limb transporters

Proximal tubule transporters

Toll, IMD, JAK/STAT pathways for immune response to pathogens

Humoral immune response to fungal and bacterial pathogens

Acetylcholine synthesis

Regulation of actin cytoskeleton

Synthesis and degradation of ketone bodies

TCA cycle

mir219 in oligodendrocyte differentiation and myelination

Proteasome degradation

Matrix metalloproteinases

Notch signaling pathway

Focal adhesion

Proteasome degradation

Cytoplasmic ribosomal proteins

Small ligand GPCRs

Statin pathway

Mitochondrial gene expression

Homologous recombination

FAS pathway and stress induction of HSP regulation

Apoptosis modulation by HSP70

Synthesis and degradation of ketone bodies

PPAR signaling pathway

MAPK signaling pathway

p38 MAPK signaling pathway

MAPK signaling pathway

p38 MAPK signaling pathway

Synthesis and degradation of ketone bodies

ACE inhibitor pathway

Insulin signaling

ACE inhibitor pathway

Microglia pathogen phagocytosis pathway

MAPK signaling pathway

Cytoplasmic ribosomal proteins

G13 signaling pathway

p38 Mapk signaling pathway

Cytokines and inflammatory response

Acetylcholine synthesis

Insulin signaling

p38 MAPK signaling pathway

MAPK signaling pathway

Ectoderm differentiation

Novel Jun-Dmp1 pathway

p38 Mapk signaling pathway

FOXA2 pathway

Renin-angiotensin system

Insulin signaling in adipocytes (diabetic condition)

Insulin signaling in adipocytes (normal condition)

Tyrobp causal network in microglia

NOTCH1 regulation of endothelial cell calcification

Host-pathogen interaction of human coronaviruses - autophagy

One-carbon metabolism

Retinoblastoma gene in cancer

One-carbon metabolism and related pathways

Toll-like receptor signaling

Lactose degradation and galactose metabolism

EDA signaling in hair follicle development

BMP2-WNT4-FOXO1 pathway in primary endometrial stromal cell differentiation

Phytochrome signaling pathway to turn on photomorphogenesis

Farnesoid X receptor pathway

PPAR-alpha pathway

Liver X receptor pathway

Endoderm differentiation

Alzheimer's disease

Peptidoglycan cytoplasmic synthesis and recycling pathways

Wnt Signaling Pathway and Pluripotency

Alanine and aspartate metabolism

Monoamine GPCRs

Cholesterol metabolism

Lung fibrosis

Estrogen signaling

Splicing factor NOVA regulated synaptic proteins

Acetate mediated promotion of metabolic syndrome

Nanoparticle-mediated activation of receptor signaling

Nanomaterial induced apoptosis

Nuclear receptors in lipid metabolism and toxicity

Nuclear receptors in lipid metabolism and toxicity

Ptf1a related regulatory pathway

Influenza A virus infection

Tumor suppressor activity of SMARCB1

Hexoses metabolism in proximal tubules

Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer

mir-193a and MVP in colon cancer metastasis

miR-509-3p alteration of YAP1/ECM axis

Apoptosis-related network due to altered Notch3 in ovarian cancer

Macrophage markers

Metastatic brain tumor

p53 signal pathway

Monoamine GPCRs

Nuclear receptors in lipid metabolism and toxicity

Leptin and adiponectin

Angiotensin II signaling (acute) in thick ascending limbs

Valproic acid pathway

Turbo design of glycolysis

Alanine and aspartate metabolism

Monoamine GPCRs

Lidocaine metabolism

Dopamine metabolism

PPAR signaling pathway

Serotonin and anxiety-related events

Nucleotide GPCRs

Glutathione metabolism

Nuclear receptors in lipid metabolism and toxicity

Nuclear receptors in lipid metabolism and toxicity

Estrogen metabolism

Aflatoxin B1 metabolism

Estrogen signaling

Estrogen metabolism

Aflatoxin B1 metabolism

Nuclear receptors in lipid metabolism and toxicity

NRF2 pathway

Iron metabolism in placenta

Photodynamic therapy-induced HIF-1 survival signaling

Photodynamic therapy-induced unfolded protein response

Novel intracellular components of RIG-I-like receptor pathway

exRNA mechanism of action and biogenesis

Caloric restriction and aging

Benzo(a)pyrene metabolism

Retinol metabolism

mRNA, protein, and metabolite inducation pathway by cyclosporin A

Tryptophan metabolism

Adipogenesis

Polyol pathway

Polyol pathway

Monoamine GPCRs

Tryptophan metabolism

Amino acid conjugation of benzoic acid

Transcription factor regulation in adipogenesis

miR-517 relationship with ARCN1 and USP1

Type III interferon signaling

Glucosinolate biosynthesis (from aromatic amino acid)

Cytosolic DNA-sensing pathway

Glutathione metabolism

Mismatch repair

Tryptophan metabolism

Interactome of polycomb repressive complex 2 (PRC2)

Dual hijack model of Vif in HIV infection

Adipogenesis

Serotonin and anxiety

Glyoxylate cycle

Chemokine signaling pathway

Homologous recombination

G1 to S cell cycle control

Hfe effect on hepcidin production

G1 to S cell cycle control

mRNA Processing

G1 to S cell cycle control

Apoptosis

G1 to S cell cycle control

Apoptosis

Apoptosis

G1 to S cell cycle control

G1 to S cell cycle control

mRNA Processing

Apoptosis

Vitamin B9 (folate) biosynthesis pathway

Metapathway biotransformation

Model of Fgf and Wnt crosstalk in tailbud

miR-127 in mesendoderm differentiation

Hfe effect on hepcidin production

Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling

Nuclear Receptors

mir-124 predicted interactions with cell cycle and differentiation

let-7 inhibition of ES cell reprogramming

eIF5A regulation in response to inhibition of the nuclear export system

Gene regulatory network modelling somitogenesis

Metapathway biotransformation

Adipogenesis

G1 to S cell cycle control

Adipogenesis

Metapathway biotransformation

Neural crest development

Type II interferon signaling (IFNG)

Homologous recombination

Mismatch repair

miR-1 in cardiac development

Mismatch repair

Homologous recombination

Mismatch repair

Mismatch repair