PPAR signaling (WP3942)

Homo sapiens

Authors

Kristina Hanspers , Denise Slenter , and Eric Weitz

Activity

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Cited In

• Stemness Analysis Uncovers That The Peroxisome Proliferator-Activated Receptor Signaling Pathway Can Mediate Fatty Acid Homeostasis In Sorafenib-Resistant Hepatocellular Carcinoma Cells (2022).
• Effects of the Phytochemical Combination PB123 on Nrf2 Activation, Gene Expression, and the Cholesterol Pathway in HepG2 Cells (2022).
• Transcriptomic Profiling of Collagenous Colitis Identifies Hallmarks of Nondestructive Inflammatory Bowel Disease (2021).
• Introducing WikiPathways as a Data-Source to Support Adverse Outcome Pathways for Regulatory Risk Assessment of Chemicals and Nanomaterials (2018).

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Organisms

Homo sapiens

Communities

Serious Request 2024 - MetaKids

Annotations

Cell Type Ontology

white fat cell cell of skeletal muscle hepatocyte fat cell

Pathway Ontology

peroxisome proliferator-activated receptor signaling pathway signaling pathway

References

1. Peroxisome proliferator-activated receptors: nuclear control of metabolism. Desvergne B, Wahli W. Endocr Rev. 1999 Oct;20(5):649–88. PubMed Europe PMC Scholia
2. The mode of action of thiazolidinediones. Hauner H. Diabetes Metab Res Rev. 2002;18 Suppl 2:S10-5. PubMed Europe PMC Scholia
3. Peroxisome proliferator-activated receptor alpha target genes. Mandard S, Müller M, Kersten S. Cell Mol Life Sci. 2004 Feb;61(4):393–416. PubMed Europe PMC Scholia
4. PPAR gamma as a metabolic regulator: insights from genomics and pharmacology. Savage DB. Expert Rev Mol Med. 2005 Jan 25;7(1):1–16. PubMed Europe PMC Scholia
5. PPARs-mediated intracellular signal transduction. Fujii H. Nihon Rinsho. 2005 Apr;63(4):565–71. PubMed Europe PMC Scholia
6. PPARs target genes. Takada I, Kato S. Nihon Rinsho. 2005 Apr;63(4):573–7. PubMed Europe PMC Scholia
7. Endogenous ligands for PPARs. Inoue H. Nihon Rinsho. 2005 Apr;63(4):578–83. PubMed Europe PMC Scholia
8. The many faces of PPARgamma. Lehrke M, Lazar MA. Cell. 2005 Dec 16;123(6):993–9. PubMed Europe PMC Scholia
9. From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions. Feige JN, Gelman L, Michalik L, Desvergne B, Wahli W. Prog Lipid Res. 2006 Mar;45(2):120–59. PubMed Europe PMC Scholia
10. PPAR gamma and human metabolic disease. Semple RK, Chatterjee VKK, O’Rahilly S. J Clin Invest. 2006 Mar;116(3):581–9. PubMed Europe PMC Scholia
11. Transcriptional regulation of metabolism. Desvergne B, Michalik L, Wahli W. Physiol Rev. 2006 Apr;86(2):465–514. PubMed Europe PMC Scholia