Phase I biotransformations, non-P450 (WP1291)
Rattus norvegicus
This pathway lists several phase 1 biotransformations and their related enzymes.
Authors
Daniela Digles , Kristina Hanspers , Martina Summer-Kutmon , Lars Willighagen , and Eric WeitzActivity
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Organisms
Rattus norvegicusCommunities
Annotations
Pathway Ontology
cytochrome P450-independent phase I biotransformation pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| thio esters | Metabolite | chebi:51277 | |
| Phosphoric acid esters | Metabolite | chebi:37734 | |
| thio esters | Metabolite | chebi:51277 | |
| carboxylic acid esters | Metabolite | chebi:33308 | |
| amides | Metabolite | chebi:32988 | |
| carboxylic acid esters | Metabolite | chebi:33308 | |
| Phosphoric acid esters | Metabolite | chebi:37734 | |
| amides | Metabolite | chebi:32988 | |
| Ces5a | GeneProduct | ensembl:ENSRNOG00000025710 | Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000159398 |
| Esd | GeneProduct | ensembl:ENSRNOG00000009512 | Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000139684 |
| Lipa | GeneProduct | ensembl:ENSRNOG00000019077 | Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000107798 |
| Pon3 | GeneProduct | ensembl:ENSRNOG00000009096 | Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000105852 |
| Ces2j | GeneProduct | ensembl:ENSRNOG00000029744 | Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000172831 |
| Pon2 | GeneProduct | ensembl:ENSRNOG00000009112 | Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000105854 |
| Ces1a | GeneProduct | ensembl:ENSRNOG00000039725 | Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000198848 |
| Pon1 | GeneProduct | ensembl:ENSRNOG00000008902 | Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000005421 |
References
- Casarett & Doull’s Essentials of Toxicology [Internet]. Klaassen C, Watkins JB III. McGraw-Hill Professional; 2003. 548 p. Available from: https://books.google.com/books/about/Casarett_Doull_s_Essentials_of_Toxicolog.html?hl=&id=pj5iQgAACAAJ OpenLibrary Worldcat