Eicosanoid synthesis (WP1318)
Danio rerio
In biochemistry, eicosanoids are signaling molecules made by oxidation of twenty-carbon essential fatty acids, (EFAs). They exert complex control over many bodily systems, mainly in inflammation or immunity, and as messengers in the central nervous system. Source: [[wikipedia:Eicosanoid|Wikipedia]]
Authors
Thomas Kelder , Christine Chichester , Martina Summer-Kutmon , and Eric WeitzActivity
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Organisms
Danio rerioCommunities
Annotations
Pathway Ontology
eicosanoid biosynthetic pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| 5-HPETE | Metabolite | hmdb:HMDB0001193 | |
| Prostaglandin H2 | Metabolite | hmdb:HMDB0001381 | |
| Leukotriene D4 | Metabolite | hmdb:HMDB0003080 | |
| Thromboxane B2 | Metabolite | hmdb:HMDB0003252 | |
| Prostaglandin I2 | Metabolite | hmdb:HMDB0001335 | |
| Prostaglandin D2 | Metabolite | hmdb:HMDB0001403 | |
| Leukotriene A4 | Metabolite | hmdb:HMDB0001337 | |
| Prostaglandin F2a | Metabolite | hmdb:HMDB0001139 | |
| Leukotriene C4 | Metabolite | hmdb:HMDB0001198 | |
| Leukotriene E4 | Metabolite | hmdb:HMDB0002200 | |
| Thromboxane A2 | Metabolite | hmdb:HMDB0001452 | |
| Arachidonic acid | Metabolite | hmdb:HMDB0001043 | |
| Leukotriene B4 | Metabolite | hmdb:HMDB0001085 | |
| LOC791800 | GeneProduct | ncbigene:791800 | |
| PTGDS | GeneProduct | ncbigene:336492 | |
| ptgesl | GeneProduct | ncbigene:799964 | |
| zgc:153024 | GeneProduct | ncbigene:768195 | |
| ptgisl | GeneProduct | ncbigene:559148 | |
| DKEY-194N13.2 | GeneProduct | ncbigene:567204 | |
| tbxas1 | GeneProduct | ncbigene:792041 | |
| ptgs1 | GeneProduct | ncbigene:246226 | |
| GGT1 | GeneProduct | ncbigene:393387 | |
| pla2g6 | GeneProduct | ncbigene:406370 | |
| ptges | GeneProduct | ncbigene:544666 | |
| pla2g6 | GeneProduct | ncbigene:406370 | |
| DKEY-194N13.2 | GeneProduct | ncbigene:567204 | |
| lta4h | GeneProduct | ncbigene:406575 | |
| ptgs2b | GeneProduct | ncbigene:559020 | |
| LOC567284 | GeneProduct | ncbigene:567284 | |
| LOC791800 | GeneProduct | ncbigene:791800 | |
| alox12 | GeneProduct | ncbigene:322732 |
References
- Prostaglandins and leukotrienes: advances in eicosanoid biology. Funk CD. Science. 2001 Nov 30;294(5548):1871–5. PubMed Europe PMC Scholia