Eicosanoid synthesis (WP972)

Bos taurus

Open in new tab Open in Newt (SBGN)
Download PNG Download SVG Download JSON Download GPML Learn more about Downloads
In biochemistry, eicosanoids are signaling molecules made by oxidation of twenty-carbon essential fatty acids, (EFAs). They exert complex control over many bodily systems, mainly in inflammation or immunity, and as messengers in the central nervous system. Source: [[wikipedia:Eicosanoid|Wikipedia]]

Authors

Thomas Kelder , Christine Chichester , Martina Summer-Kutmon , and Eric Weitz

Activity

last edited

Discuss this pathway

Check for ongoing discussions or start your own.

Cited In

Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.

Organisms

Bos taurus

Communities

Annotations

Pathway Ontology

eicosanoid biosynthetic pathway inflammatory response pathway

Cell Type Ontology

epithelial cell

Participants

Label Type Compact URI Comment
5-HETE Metabolite cas:70608-72-9
5-HPETE Metabolite hmdb:HMDB0001193
Prostaglandin H2 Metabolite hmdb:HMDB0001381
Leukotriene D4 Metabolite hmdb:HMDB0003080
Thromboxane B2 Metabolite hmdb:HMDB0003252
Prostaglandin I2 Metabolite hmdb:HMDB0001335
Prostaglandin D2 Metabolite hmdb:HMDB0001403
Leukotriene A4 Metabolite hmdb:HMDB0001337
Prostaglandin F2a Metabolite hmdb:HMDB0001139
Leukotriene C4 Metabolite hmdb:HMDB0001198
Leukotriene E4 Metabolite hmdb:HMDB0002200
12-HETE Metabolite cas:70608-72-9
15-HETE Metabolite cas:70608-72-9
Thromboxane A2 Metabolite hmdb:HMDB0001452
Arachidonic acid Metabolite hmdb:HMDB0001043
Leukotriene B4 Metabolite hmdb:HMDB0001085
12-HPETE Metabolite cas:71030-35-8
15-HPETE Metabolite cas:70981-96-3
Prostaglandin E2 Metabolite cas:363-24-6
ALOX5AP GeneProduct ensembl:ENSBTAG00000013201 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:241
PTGDS GeneProduct ensembl:ENSBTAG00000015074 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5730
PTGES2 GeneProduct ensembl:ENSBTAG00000016218 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:80142
DPEP1 GeneProduct ensembl:ENSBTAG00000033326 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1800
PTGIS GeneProduct ensembl:ENSBTAG00000017537 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5740
PLA2G2A GeneProduct ensembl:ENSBTAG00000005759 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5320
ALOX5 GeneProduct ensembl:ENSBTAG00000020319 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:240
PNPLA3 GeneProduct ensembl:ENSBTAG00000045746 HomologyConvert: Homo sapiens to Bos taurus: Original ID = H:PNPLA3
TBXAS1 GeneProduct ensembl:ENSBTAG00000020225 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6916
PTGS1 GeneProduct ensembl:ENSBTAG00000006716 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5742
GGT1 GeneProduct ensembl:ENSBTAG00000046900 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2678
PLA2G6 GeneProduct ensembl:ENSBTAG00000014015 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8398
ALOX15 GeneProduct ensembl:ENSBTAG00000011990 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:246
ALOX15B GeneProduct ensembl:ENSBTAG00000008779 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:247
PTGES GeneProduct ensembl:ENSBTAG00000019453 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9536
LTA4H GeneProduct ensembl:ENSBTAG00000016415 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4048
PGHS-2 GeneProduct ensembl:ENSBTAG00000014127 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5743
LTC4S GeneProduct ensembl:ENSBTAG00000009737 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4056
PNPLA8 GeneProduct ensembl:ENSBTAG00000024387 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:50640
ALOX12 GeneProduct ensembl:ENSBTAG00000021933 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:239

References

  1. Prostaglandins and leukotrienes: advances in eicosanoid biology. Funk CD. Science. 2001 Nov 30;294(5548):1871–5. PubMed Europe PMC Scholia