G13 signaling pathway (WP945)

Pan troglodytes

The G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cells and is essential for receptor tyrosine kinase-induced migration of fibroblast and endothelial cells. Source: [[wikipedia:G12/G13_alpha_subunits|Wikipedia]]

Authors

Thomas Kelder , Christine Chichester , Martina Summer-Kutmon , and Eric Weitz

Activity

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Cited In

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Organisms

Pan troglodytes

Communities

Annotations

Pathway Ontology

G protein mediated signaling pathway via Galpha12/Galpha13 family G protein mediated signaling pathway

Participants

Label Type Compact URI Comment
RTKN GeneProduct ensembl:ENSPTRG00000012086 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:6242
PKN1 GeneProduct ensembl:ENSPTRG00000010591 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5585
CFL2 GeneProduct ensembl:ENSPTRG00000006254 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:1073
RHPN2 GeneProduct ensembl:ENSPTRG00000010801 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:85415
RHOA GeneProduct ensembl:ENSPTRG00000014922 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:387
PFN1 GeneProduct ensembl:ENSPTRG00000008616 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5216
ARHGEF1 GeneProduct ensembl:ENSPTRG00000011039 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:9138
CYFIP1 GeneProduct ensembl:ENSPTRG00000006818 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:23191
GNA13 GeneProduct ensembl:ENSPTRG00000009551 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:10672
IQGAP2 GeneProduct ensembl:ENSPTRG00000017002 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:10788
IQGAP1 GeneProduct ensembl:ENSPTRG00000007455 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:8826
PIK3CD GeneProduct ensembl:ENSPTRG00000000120 P42338
Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5293
ARHGDIB GeneProduct ensembl:ENSPTRG00000004729 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:397
PIK3CB GeneProduct ensembl:ENSPTRG00000015452 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5291
SH3RF1 GeneProduct ensembl:ENSPTRG00000016587 Posh
Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:57630
LIMK1 GeneProduct ensembl:ENSPTRG00000045946 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:3984
MYBPH GeneProduct ensembl:ENSPTRG00000001868 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:4608
RAC1 GeneProduct ensembl:ENSPTRG00000052694 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5879
TNK2 GeneProduct ensembl:ENSPTRG00000049620 S33596
Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:10188
PAK3 GeneProduct ensembl:ENSPTRG00000022187 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5063
PIP4K2A GeneProduct ensembl:ENSPTRG00000002355 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5305
MAPK10 GeneProduct ensembl:ENSPTRG00000016244 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5602
CALM1 GeneProduct ensembl:ENSPTRG00000050292 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:801
WASL GeneProduct ensembl:ENSPTRG00000019640 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:8976
PIK3R2 GeneProduct ensembl:ENSPTRG00000010694 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5296
PPP1CB GeneProduct ensembl:ENSPTRG00000011788 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5500
WAS GeneProduct ensembl:ENSPTRG00000050143 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:7454
MAP3K4 GeneProduct ensembl:ENSPTRG00000046415 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:4216
MYL1 GeneProduct ensembl:ENSPTRG00000012879 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:4632
CIT GeneProduct ensembl:ENSPTRG00000005521 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:11113
ARHGDIG GeneProduct ensembl:ENSPTRG00000031322 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:398
ROCK1 GeneProduct ensembl:ENSPTRG00000009904 S69211
Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:6093
DIAPH1 GeneProduct ensembl:ENSPTRG00000045831 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:1729
PIK3CA GeneProduct ensembl:ENSPTRG00000015642 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:5290
CDC42 GeneProduct ensembl:ENSPTRG00000051031 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:998
RPS6KB1 GeneProduct ensembl:ENSPTRG00000009477 A41687
Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:6198
ROCK2 GeneProduct ensembl:ENSPTRG00000011658 BAA31594
Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:9475
CFL1 GeneProduct ensembl:ENSPTRG00000046419 Homology Mapping from Homo sapiens to Pan troglodytes: Original ID = L:1072

References

  1. G protein pathways. Neves SR, Ram PT, Iyengar R. Science. 2002 May 31;296(5573):1636–9. PubMed Europe PMC Scholia