ncRNAs involved in STAT3 signaling in hepatocellular carcinoma (WP4337)

Homo sapiens

Open in new tab Open in NDEx Open in Newt (SBGN)
Download PNG Download SVG Download JSON Download GPML Learn more about Downloads
This pathway describes the influence of ncRNAs on the STAT3 pathway in hepatocellular carcinoma. The model is based on Fig 4 in Klingenberg et al.

Authors

Kristina Hanspers , Friederike Ehrhart , and Eric Weitz

Activity

last edited

Discuss this pathway

Check for ongoing discussions or start your own.

Cited In

Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.

Organisms

Homo sapiens

Communities

CPTAC ExRNA

Annotations

Cell Type Ontology

stem cell hepatocyte

Disease Ontology

hepatocellular carcinoma

Pathway Ontology

altered Jak-Stat signaling pathway cancer pathway

Participants
Query Drugst.One

Label Type Compact URI Comment
JAK1 GeneProduct ensembl:ENSG00000162434
RELA GeneProduct ensembl:ENSG00000173039
IL6 GeneProduct ensembl:ENSG00000136244
IL6ST GeneProduct ensembl:ENSG00000134352
NFKB1 GeneProduct ensembl:ENSG00000109320
MIR21 GeneProduct ensembl:ENSG00000284190
IL11RA GeneProduct ensembl:ENSG00000137070
STAT3 GeneProduct ensembl:ENSG00000168610
IL11 GeneProduct ensembl:ENSG00000095752
IL6R GeneProduct ensembl:ENSG00000160712
JAK2 GeneProduct ensembl:ENSG00000096968
JAK3 GeneProduct ensembl:ENSG00000105639
ZEB1 GeneProduct ensembl:ENSG00000148516
SOX4 GeneProduct ensembl:ENSG00000124766
MIR200A GeneProduct ensembl:ENSG00000207607
MIR200B GeneProduct ensembl:ENSG00000207730
MIR200C GeneProduct ensembl:ENSG00000207713
UCA1 GeneProduct ensembl:ENSG00000214049

References

  1. Non-coding RNA in hepatocellular carcinoma: Mechanisms, biomarkers and therapeutic targets. Klingenberg M, Matsuda A, Diederichs S, Patel T. J Hepatol. 2017 Sep;67(3):603–18. PubMed Europe PMC Scholia