Circulating monocytes and cardiac macrophages in diastolic dysfunction (WP4474)
Mus musculus
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Authors
Kristina Hanspers and Martina Summer-KutmonActivity
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Cited In
- Comparative Screening of the Liver Gene Expression Profiles from Type 1 and Type 2 Diabetes Rat Models (2024).
- Isoschaftoside in Fig Leaf Tea Alleviates Nonalcoholic Fatty Liver Disease in Mice via the Regulation of Macrophage Polarity (2025).
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Organisms
Mus musculusCommunities
ExRNAAnnotations
Disease Ontology
cardiovascular system disease cardiovascular system disease hypertension hypertensionCell Type Ontology
myofibroblast cell monocyte intermediate monocyte monocyte macrophage myofibroblast cell macrophagePathway Ontology
disease pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| ROS | Metabolite | chebi:26523 | |
| Ccl2 | GeneProduct | ensembl:ENSMUSG00000035385 | |
| Il10 | GeneProduct | ensembl:ENSMUSG00000016529 | |
| Spp1 | GeneProduct | ensembl:ENSMUSG00000029304 | |
| Ccr2 | GeneProduct | ensembl:ENSMUSG00000049103 |
References
- Cardiac macrophages promote diastolic dysfunction. Hulsmans M, Sager HB, Roh JD, Valero-Muñoz M, Houstis NE, Iwamoto Y, et al. J Exp Med. 2018 Feb 5;215(2):423–40. PubMed Europe PMC Scholia