Blood clotting cascade (WP887)

Pan troglodytes

Open in new tab Open in Newt (SBGN)
Download PNG Download SVG Download JSON Download GPML Learn more about Downloads
Coagulation is a complex process by which blood forms clots. It is an important part of hemostasis (the cessation of blood loss from a damaged vessel), wherein a damaged blood vessel wall is covered by a platelet and fibrin-containing clot to stop bleeding and begin repair of the damaged vessel. Disorders of coagulation can lead to an increased risk of bleeding (hemorrhage) or clotting (thrombosis). Source: [[wikipedia:Coagulation|Wikipedia]]

Authors

Thomas Kelder , Christine Chichester , and Eric Weitz

Activity

last edited

Discuss this pathway

Check for ongoing discussions or start your own.

Cited In

Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.

Organisms

Pan troglodytes

Communities

Annotations

Pathway Ontology

coagulation cascade pathway

Participants

Label Type Compact URI Comment
F12 GeneProduct ncbigene:462304
F11 GeneProduct ncbigene:461643
F9 GeneProduct ncbigene:465887
F10 GeneProduct ncbigene:452679
VWF GeneProduct ncbigene:451773
F5 GeneProduct ncbigene:457500
F7 GeneProduct ncbigene:744785
F2 GeneProduct ncbigene:451158
F13B GeneProduct ncbigene:735857
PLAU GeneProduct ncbigene:738078
PLAT GeneProduct ncbigene:472748
SERPINB2 GeneProduct ncbigene:739078
SERPINE1 GeneProduct ncbigene:472467
PLG GeneProduct ncbigene:463117
FGB GeneProduct ncbigene:461558
FGA GeneProduct ncbigene:461559
FGG GeneProduct ncbigene:461560
F8 GeneProduct ncbigene:473838

References

  1. The current status of coagulation. Luchtman-Jones L, Broze GJ Jr. Ann Med. 1995 Feb;27(1):47–52. PubMed Europe PMC Scholia