miR-222 in exercise-induced cardiac growth (WP3938)

Homo sapiens

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miR-222 is necessary for exercise-induced cardiac growth and protects against pathological cardiac remodeling. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP3938 CPTAC Assay Portal].

Authors

Kristina Hanspers , Andika Tan , and Eric Weitz

Activity

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Cited In

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Organisms

Homo sapiens

Communities

Annotations

Pathway Ontology

microRNA pathway regulatory pathway

Cell Type Ontology

cardiac muscle cell

Participants
Query Drugst.One

Label Type Compact URI Comment
CDKN1B GeneProduct ensembl:ENSG00000111276 Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000003031
HMBOX1 GeneProduct ensembl:ENSG00000147421 Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000021972
HIPK2 GeneProduct ensembl:ENSG00000064393 Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000061436
HIPK1 GeneProduct ensembl:ENSG00000163349 Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000008730

References

  1. miR-222 is necessary for exercise-induced cardiac growth and protects against pathological cardiac remodeling. Liu X, Xiao J, Zhu H, Wei X, Platt C, Damilano F, et al. Cell Metab. 2015 Apr 7;21(4):584–95. PubMed Europe PMC Scholia